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Murcko scaffold

4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol scaffold

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
31
With full pages
8
Scaffold SMILES

S=c1[nH]nc(-c2cccnc2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol page
Murcko scaffold S=c1[nH]nc(-c2cccnc2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

4-(4-Bromophenyl)-2,4-dihydro-5-(3-pyridinyl)-3H-1,2,4-triazole-3-thione chemical structure, C13H9BrN4S, CAS 127055-61-2
4-(4-Bromophenyl)-2,4-dihydro-5-(3-pyridinyl)-3H-1,2,4-triazole-3-thione
CAS 127055-61-2C13H9BrN4S
4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C13H10N4S, CAS 5729-09-9
4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 5729-09-9C13H10N4S
4-(2,4-Dimethylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4S, CAS 519152-01-3
4-(2,4-Dimethylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 519152-01-3C15H14N4S
4-(4-Chloro-2-methylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S, CAS 578749-51-6
4-(4-Chloro-2-methylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 578749-51-6C14H11ClN4S
4-(4-Fluoro-phenyl)-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C13H9FN4S, CAS 132844-85-0
4-(4-Fluoro-phenyl)-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 132844-85-0C13H9FN4S
4-(3-Chloro-2-methylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione chemical structure, C14H11ClN4S, CAS 440638-31-3
4-(3-Chloro-2-methylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
CAS 440638-31-3C14H11ClN4S
4-(2-Methylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4S, CAS 132844-81-6
4-(2-Methylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 132844-81-6C14H12N4S
4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4OS, CAS 131090-39-6
4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 131090-39-6C14H12N4OS
4-(2,5-Dimethylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4S, CAS 517869-98-6
4-(2,5-Dimethylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
CAS 517869-98-6C15H14N4S
4-(4-Chloro-2,5-dimethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H13ClN4O2S, CAS 517870-02-9
4-(4-Chloro-2,5-dimethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 517870-02-9C15H13ClN4O2S
5-(Pyridin-3-yl)-4-[2-(trifluoromethyl)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C14H9F3N4S, CAS 132844-82-7
5-(Pyridin-3-yl)-4-[2-(trifluoromethyl)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 132844-82-7C14H9F3N4S
5-(Pyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol chemical structure, C14H9F3N4S, CAS 132844-83-8
5-(Pyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol
CAS 132844-83-8C14H9F3N4S
4-(4-Chlorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9ClN4S, CAS 127055-60-1
4-(4-Chlorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 127055-60-1C13H9ClN4S
4-(3-Chloro-4-fluorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H8ClFN4S, CAS 727371-76-8
4-(3-Chloro-4-fluorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 727371-76-8C13H8ClFN4S
4-(4-Butylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione chemical structure, C17H18N4S, CAS 517869-99-7
4-(4-Butylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
CAS 517869-99-7C17H18N4S
4-(2-Bromo-4-methylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione chemical structure, C14H11BrN4S, CAS 839685-90-4
4-(2-Bromo-4-methylphenyl)-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
CAS 839685-90-4C14H11BrN4S
4-[2-Chloro-5-(trifluoromethyl)phenyl]-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione chemical structure, C14H8ClF3N4S, CAS 838894-53-4
4-[2-Chloro-5-(trifluoromethyl)phenyl]-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
CAS 838894-53-4C14H8ClF3N4S
4-(2,6-Diethylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C17H18N4S, CAS 380442-83-1
4-(2,6-Diethylphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 380442-83-1C17H18N4S
4-[2-(Propan-2-yl)phenyl]-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C16H16N4S, CAS 380442-88-6
4-[2-(Propan-2-yl)phenyl]-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 380442-88-6C16H16N4S
4-{4-[(Difluoromethyl)sulfanyl]phenyl}-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H10F2N4S2, CAS 380349-27-9
4-{4-[(Difluoromethyl)sulfanyl]phenyl}-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 380349-27-9C14H10F2N4S2
4-(2-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4OS, CAS 452053-06-4
4-(2-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 452053-06-4C15H14N4OS
4-(4-Ethoxy-phenyl)-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C15H14N4OS, CAS 111114-78-4
4-(4-Ethoxy-phenyl)-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 111114-78-4C15H14N4OS
4-(2-Fluorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9FN4S, CAS 722465-56-7
4-(2-Fluorophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 722465-56-7C13H9FN4S
5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol chemical structure, C14H8ClF3N4S, CAS 306936-75-4
5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazole-3-thiol
CAS 306936-75-4C14H8ClF3N4S