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Murcko scaffold

1-[(Pyridin-2-yl)methyl]piperazine scaffold

146 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
146
With full pages
5
Scaffold SMILES

c1ccc(CN2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[(Pyridin-2-yl)methyl]piperazine page
Murcko scaffold c1ccc(CN2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 146 chemicals

1-(Propylsulfonyl)-4-(2-pyridylmethyl)piperazine chemical structure, C13H21N3O2S, CAS 441745-81-9
1-(Propylsulfonyl)-4-(2-pyridylmethyl)piperazine
CAS 441745-81-9C13H21N3O2S
1-[(Pyridin-2-yl)methyl]piperazine chemical structure, C10H15N3, CAS 55579-01-6
1-[(Pyridin-2-yl)methyl]piperazine
CAS 55579-01-6C10H15N3
2-[(4-Methylpiperazin-1-yl)methyl]pyridin-3-ol chemical structure, C11H17N3O, CAS 95380-59-9
2-[(4-Methylpiperazin-1-yl)methyl]pyridin-3-ol
CAS 95380-59-9C11H17N3O
1-Isopropyl-4-(pyridin-2-ylmethyl)piperazine chemical structure, C13H21N3, CAS 674808-02-7
1-Isopropyl-4-(pyridin-2-ylmethyl)piperazine
CAS 674808-02-7C13H21N3
[4-(tert-Butoxycarbonyl)piperazin-1-yl](pyridin-2-yl)acetic acid chemical structure, C16H23N3O4, CAS 885274-48-6
[4-(tert-Butoxycarbonyl)piperazin-1-yl](pyridin-2-yl)acetic acid
CAS 885274-48-6C16H23N3O4
1-[(5-Ethyl-2-pyridinyl)methyl]piperazine chemical structure, C12H19N3, CAS 524673-91-4
1-[(5-Ethyl-2-pyridinyl)methyl]piperazine
CAS 524673-91-4C12H19N3
1-[(3-Methylpyridin-2-yl)methyl]piperazine chemical structure, C11H17N3, CAS 524673-92-5
1-[(3-Methylpyridin-2-yl)methyl]piperazine
CAS 524673-92-5C11H17N3
1-[(5-Methylpyridin-2-yl)methyl]piperazine chemical structure, C11H17N3, CAS 524673-90-3
1-[(5-Methylpyridin-2-yl)methyl]piperazine
CAS 524673-90-3C11H17N3
1-[1-(Pyridin-2-yl)ethyl]piperazine chemical structure, C11H17N3, CAS 34581-20-9
1-[1-(Pyridin-2-yl)ethyl]piperazine
CAS 34581-20-9C11H17N3
1-Methyl-4-[(pyridin-2-yl)methyl]piperazine chemical structure, C11H17N3, CAS 100158-57-4
1-Methyl-4-[(pyridin-2-yl)methyl]piperazine
CAS 100158-57-4C11H17N3
Piperazine, 1-ethyl-4-(2-pyridinylmethyl)- chemical structure, C12H19N3, CAS 631858-22-5
Piperazine, 1-ethyl-4-(2-pyridinylmethyl)-
CAS 631858-22-5C12H19N3
1-[(6-Methylpyridin-2-yl)methyl]piperazine trihydrochloride chemical structure, C11H17N3, CAS 524673-89-0
1-[(6-Methylpyridin-2-yl)methyl]piperazine trihydrochloride
CAS 524673-89-0C11H17N3
tert-Butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate chemical structure, C15H23N3O2, CAS 77278-93-4
tert-Butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate
CAS 77278-93-4C15H23N3O2
Piperazine, 1-methyl-4-[(1S)-1-(2-pyridinyl)ethyl]- chemical structure, C12H19N3, CAS 779328-49-3
Piperazine, 1-methyl-4-[(1S)-1-(2-pyridinyl)ethyl]-
CAS 779328-49-3C12H19N3
6-[(4-Methylpiperazin-1-yl)methyl]pyridin-2-amine chemical structure, C11H18N4, CAS 639009-18-0
6-[(4-Methylpiperazin-1-yl)methyl]pyridin-2-amine
CAS 639009-18-0C11H18N4
Methyl 6-((4-methylpiperazin-1-yl)methyl)nicotinate chemical structure, C13H19N3O2, CAS 132521-81-4
Methyl 6-((4-methylpiperazin-1-yl)methyl)nicotinate
CAS 132521-81-4C13H19N3O2
tert-Butyl 4-(2-methoxy-2-oxo-1-(pyridin-2-yl)ethyl)piperazine-1-carboxylate chemical structure, C17H25N3O4, CAS 890090-44-5
tert-Butyl 4-(2-methoxy-2-oxo-1-(pyridin-2-yl)ethyl)piperazine-1-carboxylate
CAS 890090-44-5C17H25N3O4
1-((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)piperazine chemical structure, C13H21N3O, CAS 919741-97-2
1-((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)piperazine
CAS 919741-97-2C13H21N3O
1-Methyl-4-[(6-methyl-2-pyridinyl)methyl]piperazine chemical structure, C12H19N3, CAS 1876274-37-1
1-Methyl-4-[(6-methyl-2-pyridinyl)methyl]piperazine
CAS 1876274-37-1C12H19N3
1-((5-Bromopyridin-2-yl)methyl)-4-ethylpiperazine chemical structure, C12H18BrN3, CAS 364794-76-3
1-((5-Bromopyridin-2-yl)methyl)-4-ethylpiperazine
CAS 364794-76-3C12H18BrN3
1-((6-Bromopyridin-2-yl)methyl)-4-methylpiperazine chemical structure, C11H16BrN3, CAS 364794-64-9
1-((6-Bromopyridin-2-yl)methyl)-4-methylpiperazine
CAS 364794-64-9C11H16BrN3
1-[(5-Bromopyridin-2-yl)methyl]-4-methylpiperazine chemical structure, C11H16BrN3, CAS 364794-75-2
1-[(5-Bromopyridin-2-yl)methyl]-4-methylpiperazine
CAS 364794-75-2C11H16BrN3
1-[(6-Bromo-2-pyridinyl)methyl]-4-ethylpiperazine chemical structure, C12H18BrN3, CAS 364794-60-5
1-[(6-Bromo-2-pyridinyl)methyl]-4-ethylpiperazine
CAS 364794-60-5C12H18BrN3
1-Pyridin-2-ylmethyl-piperazine hydrochloride chemical structure, C10H16ClN3, CAS 1174310-77-0
1-Pyridin-2-ylmethyl-piperazine hydrochloride
CAS 1174310-77-0C10H16ClN3