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Murcko scaffold

Ring system with 3 rings and 15 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
16
With full pages
4
Scaffold SMILES

c1cc(-c2ccc3c(c2)OCCO3)on1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(-c2ccc3c(c2)OCCO3)on1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazole-3-carboxylic acid chemical structure, C12H9NO5, CAS 763109-72-4
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazole-3-carboxylic acid
CAS 763109-72-4C12H9NO5
(5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolyl)methanol chemical structure, C12H11NO4, CAS 763109-37-1
(5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolyl)methanol
CAS 763109-37-1C12H11NO4
3-(Chloromethyl)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-oxazole chemical structure, C12H10ClNO3, CAS 941235-02-5
3-(Chloromethyl)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-oxazole
CAS 941235-02-5C12H10ClNO3
Ethyl 5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-carboxylate chemical structure, C14H13NO5, CAS 925007-02-9
Ethyl 5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-carboxylate
CAS 925007-02-9C14H13NO5
(5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-yl)methanamine chemical structure, C12H12N2O3, CAS 1018605-08-7
(5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-yl)methanamine
CAS 1018605-08-7C12H12N2O3
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolecarboxaldehyde chemical structure, C12H9NO4, CAS 925007-18-7
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolecarboxaldehyde
CAS 925007-18-7C12H9NO4
[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)isoxazol-3-yl]acetic acid chemical structure, C13H11NO5, CAS 1018663-30-3
[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)isoxazol-3-yl]acetic acid
CAS 1018663-30-3C13H11NO5
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolecarbohydrazide chemical structure, C12H11N3O4, CAS 763109-45-1
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-isoxazolecarbohydrazide
CAS 763109-45-1C12H11N3O4
2-(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)acetonitrile chemical structure, C13H10N2O3, CAS 1207031-99-9
2-(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)acetonitrile
CAS 1207031-99-9C13H10N2O3
N-((5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)methyl)-2-methoxyacetamide chemical structure, C15H16N2O5, CAS 1210118-23-2
N-((5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)methyl)-2-methoxyacetamide
CAS 1210118-23-2C15H16N2O5
2-(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)-N-isopropylacetamide chemical structure, C16H18N2O4, CAS 1208709-33-4
2-(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)-N-isopropylacetamide
CAS 1208709-33-4C16H18N2O4
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-amine chemical structure, C11H10N2O3, CAS 1267010-33-2
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-amine
CAS 1267010-33-2C11H10N2O3
Methyl 5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-carboxylate chemical structure, C13H11NO5, CAS 925004-56-4
Methyl 5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-carboxylate
CAS 925004-56-4C13H11NO5
5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-methylisoxazole chemical structure, C12H11NO3, CAS 1891047-62-3
5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-methylisoxazole
CAS 1891047-62-3C12H11NO3
[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-yl]methanamine hydrochloride chemical structure, C12H13ClN2O3, CAS 1351647-81-8
[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-3-yl]methanamine hydrochloride
CAS 1351647-81-8C12H13ClN2O3
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-4-amine chemical structure, C11H10N2O3, CAS 2107215-99-4
5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-oxazol-4-amine
CAS 2107215-99-4C11H10N2O3