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Murcko scaffold

Ring system with 4 rings and 25 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
5
With full pages
3
Scaffold SMILES

C(=NNc1nc(-c2cccnc2)nc2ccccc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NNc1nc(-c2cccnc2)nc2ccccc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]-2-pyridin-3-ylquinazolin-4-amine chemical structure, C22H19N5O2, CAS 378761-96-7
N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]-2-pyridin-3-ylquinazolin-4-amine
CAS 378761-96-7C22H19N5O2
(4E)-4-{(2E)-[1-(3,4-Dimethoxyphenyl)ethylidene]hydrazinylidene}-2-(pyridin-3-yl)-3,4-dihydroquinazoline chemical structure, C23H21N5O2, CAS 380164-29-4
(4E)-4-{(2E)-[1-(3,4-Dimethoxyphenyl)ethylidene]hydrazinylidene}-2-(pyridin-3-yl)-3,4-dihydroquinazoline
CAS 380164-29-4C23H21N5O2
(E)-2-((2-(2-(Pyridin-3-yl)quinazolin-4-yl)hydrazono)methyl)phenol chemical structure, C20H15N5O, CAS 378756-43-5
(E)-2-((2-(2-(Pyridin-3-yl)quinazolin-4-yl)hydrazono)methyl)phenol
CAS 378756-43-5C20H15N5O
(E)-2-Methoxy-6-((2-(2-(pyridin-3-yl)quinazolin-4-yl)hydrazono)methyl)phenol chemical structure, C21H17N5O2, CAS 380887-50-3
(E)-2-Methoxy-6-((2-(2-(pyridin-3-yl)quinazolin-4-yl)hydrazono)methyl)phenol
CAS 380887-50-3C21H17N5O2
4-[(E)-{2-[2-(Pyridin-3-yl)quinazolin-4-yl]hydrazinylidene}methyl]benzene-1,3-diol chemical structure, C20H15N5O2, CAS 378772-35-1
4-[(E)-{2-[2-(Pyridin-3-yl)quinazolin-4-yl]hydrazinylidene}methyl]benzene-1,3-diol
CAS 378772-35-1C20H15N5O2