Murcko scaffold
Ring system with 7 rings and 69 atoms
42 chemicals on CompoundList share this ring system.
- Rings
- 7
- Scaffold atoms
- 69
- Chemicals
- 42
- With full pages
- 6
Scaffold SMILES
O=C1CNC(=O)C2CCCN2C(=O)CNC(=O)C(NC(=O)c2cc(=O)cc3oc4cccc(C(=O)NC5COC(=O)CNC(=O)CNC(=O)C6CCCN6C(=O)CNC5=O)c4nc2-3)COC(=O)CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 42 of 42 chemicals
Actinomycin d, 2-deamino-
CAS 10118-32-8C62H85N11O16
Actinomycin D, 2-N-(gamma-hydroxypropyl)-
CAS 57154-63-9C65H92N12O17
Chloroactinomycin D
CAS 21392-13-2C62H84ClN11O16
Actinomycin D, 7-(octylamino)-
CAS 67237-00-7C70H103N13O16
N-(10-Aminodecyl)actinomycin D
CAS 71608-85-0C72H107N13O16
7-Methoxyactinomycin D dihydrate
CAS 78542-23-1C63H88N12O17
7-Ethoxyactinomycin D dihydrate
CAS 78542-24-2C64H90N12O17
7-Butoxyactinomycin D trihydrate
CAS 78542-26-4C66H94N12O17
7-(Hexyloxy)actinomycin D
CAS 78542-27-5C68H98N12O17
7-(Heptyloxy)actinomycin D
CAS 78542-28-6C69H100N12O17
N-Propylactinomycin D dihydrate
CAS 78542-35-5C65H92N12O16
N-Butylactinomycin D
CAS 78542-36-6C66H94N12O16
N-Pentylactinomycin D
CAS 78542-37-7C67H96N12O16
N-Hexylactinomycin D
CAS 78542-38-8C68H98N12O16
N-Nonylactinomycin D
CAS 78542-39-9C71H104N12O16
N-Undecylactinomycin D
CAS 78542-40-2C73H108N12O16
N-(4-Aminobutyl)actinomycin D dihydrate
CAS 78542-41-3C66H95N13O16
N-(5-Aminopentyl)actinomycin D hydrate
CAS 78542-42-4C67H97N13O16
N-(8-Aminooctyl)actinomycin D
CAS 78542-43-5C70H103N13O16
N(sup 2)-3'-Aminopropylactinomycin D dihydrate
CAS 78542-45-7C65H93N13O16
7-Hydroxyactinomycin D
CAS 21478-73-9C62H86N12O17
Actinomycin D, 7-bromo-
CAS 10030-10-1C62H85BrN12O16
Actinomycin D, 2A-D-leucine-
CAS 19864-70-1C63H88N12O16
Actinomycin D, 8-amino-7-hydroxy-
CAS 95045-12-8C62H87N13O17
- Actinomycin I from Streptomyces antibioticus18865-46-8C62H86N12O17
- Actinomycin E21402-42-2C66H94N12O16
- 53 suppliersDactinomycin50-76-0C62H86N12O16
- 7-Azidoactinomycin D121051-59-0C62H85N15O16
- 1 suppliersActinomycin C8052-16-2C63H88N12O16
- Actinomycin C22612-14-8C63H88N12O16
- 7-((Hydroxyacetyl)amino)actinomycin D ester with L-valine, monoacetate72766-93-9C71H102N14O21
- 7 suppliers7-Aminoactinomycin D7240-37-1C62H87N13O16
- Actinomycin G3910780-93-7C61H84N12O18
- Actinomycin G4910780-94-8C61H84N12O17
- Actinomycin D, 7-nitro-6184-25-4C62H85N13O18
- 7-((Hydroxyacetyl)amino)actinomycin D ester with L-valylglycoloyl-L-valine, monoacetate72751-57-6C78H113N15O24
- Actinomycin C36156-47-4C64H90N12O16
- Actinomycin E11402-41-1C65H92N12O16
- 1-N,9-N-bis[(3R,6S,7R,10S,16R)-3,10-bis(1,1,1,2,3,3,3-heptatritiopropan-2-yl)-2,5,9,12,15-pentaoxo-3,4,6,7,10,13,13,16,17,17,18,18,19,19-tetradecatritio-7,11,14-tris(tritritiomethyl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-2-(ditritioamino)-3-oxo-1-N,9-N,7,8-tetratritio-4,6-bis(tritritiomethyl)phenoxazine-1,9-dicarboxamide6412-01-7C62H86N12O16
- 2-Amino-4,6-dimethyl-7-nitro-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamideC62H85N13O18
- 7-Propoxyactinomycin D dihydrate78542-25-3C65H96N12O19
- 4a-(N-(3-Methoxy-3-oxopropyl)glycine)-4b-(N-(3-methoxy-3-oxopropyl)glycine)-actinomycin D131545-49-8C68H94N12O20
Related scaffolds
Same ring framework with different atoms or bond orders
