CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
4
With full pages
0
Scaffold SMILES

O=C(C=Cc1c[nH]c2ccccc12)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1c[nH]c2ccccc12)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

(E)-3-(5-Bromo-1H-indol-3-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide chemical structure, C20H16BrN3O, CAS 485367-39-3
(E)-3-(5-Bromo-1H-indol-3-yl)-2-cyano-N-(2-phenylethyl)prop-2-enamide
CAS 485367-39-3C20H16BrN3O
2-Cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(1H-indol-3-yl)prop-2-enamide chemical structure, C22H21N3O3, CAS 717826-68-1
2-Cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(1H-indol-3-yl)prop-2-enamide
CAS 717826-68-1C22H21N3O3
(E)-N-[2-(2-Ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)prop-2-enamide chemical structure, C22H24N2O3, CAS 2234281-75-3
(E)-N-[2-(2-Ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)prop-2-enamide
CAS 2234281-75-3C22H24N2O3
Orb1298001 chemical structure, C23H24N2O3, CAS 2234271-86-2
Orb1298001
CAS 2234271-86-2C23H24N2O3