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Murcko scaffold

Ring system with 2 rings and 11 atoms

38 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
38
With full pages
5
Scaffold SMILES

C=C1CC(=O)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1CC(=O)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

Ethyl (2-(aminocarbonyl)-2-chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)(cyano)acetate chemical structure, C15H11ClN2O4, CAS 62681-22-5
Ethyl (2-(aminocarbonyl)-2-chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)(cyano)acetate
CAS 62681-22-5C15H11ClN2O4
3-(Dicyanomethylidene)indan-1-one chemical structure, C12H6N2O, CAS 1080-74-6
3-(Dicyanomethylidene)indan-1-one
CAS 1080-74-6C12H6N2O
1-Ethylidene-3-oxo-2,3-dihydro-1H-indene-2-carboxamide chemical structure, C12H11NO2, CAS 91569-09-4
1-Ethylidene-3-oxo-2,3-dihydro-1H-indene-2-carboxamide
CAS 91569-09-4C12H11NO2
(E)-1-(3-Chloropropylidene)-3-oxo-2,3-dihydro-1H-indene-2-carboxamide chemical structure, C13H12ClNO2, CAS 66281-79-6
(E)-1-(3-Chloropropylidene)-3-oxo-2,3-dihydro-1H-indene-2-carboxamide
CAS 66281-79-6C13H12ClNO2
2-(7-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C12H5ClN2O, CAS 123313-95-1
2-(7-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 123313-95-1C12H5ClN2O
(1E)-1-(3-Chloropropylidene)-3-oxoindene-2-carboxamide chemical structure, C13H12ClNO2
(1E)-1-(3-Chloropropylidene)-3-oxoindene-2-carboxamide
C13H12ClNO2
2-Methyl-3-methylidene-2,3-dihydro-1H-inden-1-one chemical structure, C11H10O, CAS 88122-34-3
2-Methyl-3-methylidene-2,3-dihydro-1H-inden-1-one
CAS 88122-34-3C11H10O
3-(2-Oxopropylidene)-2,3-dihydro-1H-inden-1-one chemical structure, C12H10O2, CAS 109058-04-0
3-(2-Oxopropylidene)-2,3-dihydro-1H-inden-1-one
CAS 109058-04-0C12H10O2
2-Methyl-3-methylidene-2-(propan-2-yl)-2,3-dihydro-1H-inden-1-one chemical structure, C14H16O, CAS 88096-25-7
2-Methyl-3-methylidene-2-(propan-2-yl)-2,3-dihydro-1H-inden-1-one
CAS 88096-25-7C14H16O
2-Methyl-3-methylidene-2-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-one chemical structure, C14H14O, CAS 88096-22-4
2-Methyl-3-methylidene-2-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-one
CAS 88096-22-4C14H14O
2-Butyl-2-methyl-3-methylidene-2,3-dihydro-1H-inden-1-one chemical structure, C15H18O, CAS 88096-21-3
2-Butyl-2-methyl-3-methylidene-2,3-dihydro-1H-inden-1-one
CAS 88096-21-3C15H18O
2-Ethyl-2-methyl-3-methylidene-2,3-dihydro-1H-inden-1-one chemical structure, C13H14O, CAS 88096-20-2
2-Ethyl-2-methyl-3-methylidene-2,3-dihydro-1H-inden-1-one
CAS 88096-20-2C13H14O
1-(3-Chloropropylidene)-3-oxoindene-2-carboxamide chemical structure, C13H12ClNO2
1-(3-Chloropropylidene)-3-oxoindene-2-carboxamide
C13H12ClNO2
2-(7-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C12H5BrN2O, CAS 507484-46-0
2-(7-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 507484-46-0C12H5BrN2O
2-[5(6)-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene]malononitrile chemical structure, C12H5BrN2O, CAS 507484-47-1
2-[5(6)-Bromo-3-oxo-2,3-dihydro-1H-inden-1-ylidene]malononitrile
CAS 507484-47-1C12H5BrN2O
2-(6-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C12H5ClN2O, CAS 507484-48-2
2-(6-Chloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 507484-48-2C12H5ClN2O
(6,7-Dichloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile chemical structure, C12H4Cl2N2O, CAS 507484-49-3
(6,7-Dichloro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile
CAS 507484-49-3C12H4Cl2N2O
3-(Dicyanomethylene)-1-oxo-2,3-dihydro-1H-indene-5-carboxylic acid chemical structure, C13H6N2O3, CAS 507484-52-8
3-(Dicyanomethylene)-1-oxo-2,3-dihydro-1H-indene-5-carboxylic acid
CAS 507484-52-8C13H6N2O3
2-(5(6)-Fluoro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C12H5FN2O, CAS 507484-54-0
2-(5(6)-Fluoro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 507484-54-0C12H5FN2O
(7-Nitro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile chemical structure, C12H5N3O3, CAS 507484-55-1
(7-Nitro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile
CAS 507484-55-1C12H5N3O3
2-(6-Methoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C13H8N2O2, CAS 507484-59-5
2-(6-Methoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 507484-59-5C13H8N2O2
2-(6-Methyl-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C13H8N2O, CAS 507484-61-9
2-(6-Methyl-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 507484-61-9C13H8N2O
2-(5,6-Dimethyl-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile chemical structure, C14H10N2O, CAS 2047352-89-4
2-(5,6-Dimethyl-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile
CAS 2047352-89-4C14H10N2O
2-(5-Butoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile compound with 2-(6-butoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile (1:1) chemical structure, C32H28N4O4, CAS 2229824-62-6
2-(5-Butoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile compound with 2-(6-butoxy-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile (1:1)
CAS 2229824-62-6C32H28N4O4