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Murcko scaffold

(Pyridin-4-yl)-3H-pyrimidin-4-one scaffold

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
30
With full pages
6
Scaffold SMILES

O=c1ccnc(-c2ccncc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (Pyridin-4-yl)-3H-pyrimidin-4-one page
Murcko scaffold O=c1ccnc(-c2ccncc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

(Pyridin-4-yl)-3H-pyrimidin-4-one chemical structure, C9H7N3O, CAS 81664-94-0
(Pyridin-4-yl)-3H-pyrimidin-4-one
CAS 81664-94-0C9H7N3O
5-Methoxy-2-(4-pyridinyl)-4-pyrimidinol chemical structure, C10H9N3O2, CAS 133661-37-7
5-Methoxy-2-(4-pyridinyl)-4-pyrimidinol
CAS 133661-37-7C10H9N3O2
4-Hydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C10H7N3O3, CAS 56406-43-0
4-Hydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxylic acid
CAS 56406-43-0C10H7N3O3
Ethyl 4-hydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxylate chemical structure, C12H11N3O3, CAS 56406-44-1
Ethyl 4-hydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxylate
CAS 56406-44-1C12H11N3O3
2-(Pyridin-4-yl)pyrimidine-4,6-diol chemical structure, C9H7N3O2, CAS 204394-76-3
2-(Pyridin-4-yl)pyrimidine-4,6-diol
CAS 204394-76-3C9H7N3O2
5-(1-Methylethyl)-2-(4-pyridinyl)-4(3H)-pyrimidinone chemical structure, C12H13N3O, CAS 1044771-52-9
5-(1-Methylethyl)-2-(4-pyridinyl)-4(3H)-pyrimidinone
CAS 1044771-52-9C12H13N3O
5-Nitro-2-(pyridin-4-yl)pyrimidine-4,6-diol chemical structure, C9H6N4O4, CAS 1188094-95-2
5-Nitro-2-(pyridin-4-yl)pyrimidine-4,6-diol
CAS 1188094-95-2C9H6N4O4
4,6-Dihydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxamide chemical structure, C10H8N4O3, CAS 1245645-66-2
4,6-Dihydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxamide
CAS 1245645-66-2C10H8N4O3
Methyl 1,6-dihydro-6-oxo-2-(4-pyridinyl)-5-pyrimidinecarboxylate chemical structure, C11H9N3O3, CAS 1239789-16-2
Methyl 1,6-dihydro-6-oxo-2-(4-pyridinyl)-5-pyrimidinecarboxylate
CAS 1239789-16-2C11H9N3O3
2-(4-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinol chemical structure, C10H6F3N3O, CAS 204394-60-5
2-(4-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinol
CAS 204394-60-5C10H6F3N3O
6-((Methylsulfanyl)methyl)-2-(4-pyridinyl)-4-pyrimidinol chemical structure, C11H11N3OS, CAS 478031-31-1
6-((Methylsulfanyl)methyl)-2-(4-pyridinyl)-4-pyrimidinol
CAS 478031-31-1C11H11N3OS
6-Methyl-2-(pyridin-4-yl)pyrimidin-4(3H)-one chemical structure, C10H9N3O, CAS 59341-68-3
6-Methyl-2-(pyridin-4-yl)pyrimidin-4(3H)-one
CAS 59341-68-3C10H9N3O
6-(Methoxymethyl)-2-(4-pyridyl)pyrimidin-4-ol chemical structure, C11H11N3O2, CAS 866145-30-4
6-(Methoxymethyl)-2-(4-pyridyl)pyrimidin-4-ol
CAS 866145-30-4C11H11N3O2
5,6-Diamino-2-(pyridin-4-yl)pyrimidin-4(3H)-one chemical structure, C9H9N5O, CAS 106823-91-0
5,6-Diamino-2-(pyridin-4-yl)pyrimidin-4(3H)-one
CAS 106823-91-0C9H9N5O
6-Amino-2-(pyridin-4-yl)pyrimidin-4-ol chemical structure, C9H8N4O, CAS 61310-39-2
6-Amino-2-(pyridin-4-yl)pyrimidin-4-ol
CAS 61310-39-2C9H8N4O
5,6-Dimethyl-2-(pyridin-4-yl)pyrimidin-4-ol chemical structure, C11H11N3O, CAS 204394-40-1
5,6-Dimethyl-2-(pyridin-4-yl)pyrimidin-4-ol
CAS 204394-40-1C11H11N3O
6-Ethyl-2-(pyridin-4-yl)-3,4-dihydropyrimidin-4-one chemical structure, C11H11N3O, CAS 1146290-21-2
6-Ethyl-2-(pyridin-4-yl)-3,4-dihydropyrimidin-4-one
CAS 1146290-21-2C11H11N3O
6-Propyl-2-(pyridin-4-yl)pyrimidin-4(1H)-one chemical structure, C12H13N3O, CAS 61310-32-5
6-Propyl-2-(pyridin-4-yl)pyrimidin-4(1H)-one
CAS 61310-32-5C12H13N3O
6-Oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidine-4-carboxylic acid chemical structure, C10H7N3O3, CAS 84660-14-0
6-Oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidine-4-carboxylic acid
CAS 84660-14-0C10H7N3O3
5-Chloro-6-methyl-2-(pyridin-4-yl)pyrimidin-4-ol chemical structure, C10H8ClN3O, CAS 1239786-71-0
5-Chloro-6-methyl-2-(pyridin-4-yl)pyrimidin-4-ol
CAS 1239786-71-0C10H8ClN3O
2-(2-Bromopyridin-4-yl)-5-hydroxy-3-methylpyrimidin-4(3H)-one chemical structure, C10H8BrN3O2, CAS 1333240-21-3
2-(2-Bromopyridin-4-yl)-5-hydroxy-3-methylpyrimidin-4(3H)-one
CAS 1333240-21-3C10H8BrN3O2
2-[4-Methyl-6-oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidin-5-yl]acetic acid chemical structure, C12H11N3O3, CAS 1146290-12-1
2-[4-Methyl-6-oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidin-5-yl]acetic acid
CAS 1146290-12-1C12H11N3O3
3-[4-Methyl-6-oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidin-5-yl]propanoic acid chemical structure, C13H13N3O3, CAS 1210644-04-4
3-[4-Methyl-6-oxo-2-(pyridin-4-yl)-1,6-dihydropyrimidin-5-yl]propanoic acid
CAS 1210644-04-4C13H13N3O3
2-(2-Chloropyridin-4-yl)-6-methyl-3,4-dihydropyrimidin-4-one chemical structure, C10H8ClN3O, CAS 1258640-22-0
2-(2-Chloropyridin-4-yl)-6-methyl-3,4-dihydropyrimidin-4-one
CAS 1258640-22-0C10H8ClN3O