CompoundList
Sign in
Murcko scaffold

Ring system with 8 rings and 39 atoms

5 chemicals on CompoundList share this ring system.

Rings
8
Scaffold atoms
39
Chemicals
5
With full pages
2
Scaffold SMILES

O=C1OCC2C(OC3CCC4OC(c5cccs5)OCC4O3)c3cc4c(cc3C(c3ccccc3)C12)OCO4

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCC2C(OC3CCC4OC(c5cccs5)OCC4O3)c3cc4c(cc3C(c3ccccc3)C12)OCO4

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

RefChem:1074905 chemical structure, C32H32O13S, CAS 125851-00-5
RefChem:1074905
CAS 125851-00-5C32H32O13S
Podophyllotoxin O-thenylidene-beta-D-glucopyranoside chemical structure, C33H34O13S, CAS 35317-31-8
Podophyllotoxin O-thenylidene-beta-D-glucopyranoside
CAS 35317-31-8C33H34O13S
(5aR,8aR,9R)-5-[[(4aR,7R,8R,8aS)-7,8-Dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one chemical structure, C32H32O13S, CAS 53956-10-8
(5aR,8aR,9R)-5-[[(4aR,7R,8R,8aS)-7,8-Dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
CAS 53956-10-8C32H32O13S
Teniposide chemical structure, C32H32O13S, CAS 29767-20-2
Teniposide
CAS 29767-20-2C32H32O13S
Teniposide catechol chemical structure, C31H30O13S, CAS 142044-45-9
Teniposide catechol
CAS 142044-45-9C31H30O13S