Murcko scaffold
Tetrahydro-2H-thiopyran 1-oxide scaffold
46 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 46
- With full pages
- 7
Scaffold SMILES
O=S1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 46 of 46 chemicals
Tetrahydro-2H-thiopyran 1-oxide
CAS 4988-34-5C5H10OS
2H-Thiopyran, 3-butyltetrahydro-, 1-oxide
CAS 61639-14-3C9H18OS
2H-Thiopyran, 3-hexyltetrahydro-, 1-oxide
CAS 61639-15-4C11H22OS
2H-Thiopyran, tetrahydro-4-octyl-, 1-oxide
CAS 64803-74-3C13H26OS
NV-31
CAS 335259-33-1C9H18O2S
4-Amino-1lambda4-thian-1-one
CAS 1158698-54-4C5H11NOS
3-Hydroxytetrahydro-2H-thiopyran 1-oxide
CAS 107319-08-4C5H10O2S
(1R,2S)-2-Propan-2-ylthiane 1-oxide
CAS 108306-87-2C8H16OS
3-Aminotetrahydro-2H-thiopyran 1-oxide
CAS 1439896-09-9C5H11NOS
Trans-3-Aminotetrahydro-2H-thiopyran1-oxide
C5H11NOS
Rel-(1R,3S)-3-aminotetrahydro-2H-thiopyran 1-oxide
C5H11NOS
4-Hydroxy-1lambda4-thian-1-one
CAS 89211-29-0C5H10O2S
4-Propan-2-ylthiane 1-oxide
CAS 60153-40-4C8H16OS
3,3-Dimethyl-1lambda~4~-thian-1-one
CAS 31815-13-1C7H14OS
4,4-Dimethyl-1lambda~4~-thian-1-one
CAS 31815-15-3C7H14OS
4-(Methylamino)-1lambda4-thian-1-one hydrochloride
CAS 1354951-30-6C6H14ClNOS
4-(Methylamino)-1lambda4-thian-1-one
CAS 1303855-40-4C6H13NOS
(3R)-1-Oxothian-3-amine
C5H11NOS
Methyl 3-((1-oxidotetrahydro-2H-thiopyran-4-yl)amino)propanoate
CAS 1249758-94-8C9H17NO3S
4-((3-(Vinyloxy)propyl)amino)tetrahydro-2H-thiopyran 1-oxide
CAS 1249500-78-4C10H19NO2S
4-((4-Methylpentan-2-yl)amino)tetrahydro-2H-thiopyran 1-oxide
CAS 1247629-63-5C11H23NOS
4-((3-Methoxypropyl)amino)tetrahydro-2H-thiopyran 1-oxide
CAS 1247612-56-1C9H19NO2S
N-(2-((1-Oxidotetrahydro-2H-thiopyran-4-yl)amino)ethyl)acetamide
CAS 1249989-18-1C9H18N2O2S
Ethanone, 1-(tetrahydro-1-oxido-2H-thiopyran-3-yl)-
CAS 332041-55-1C7H12O2S
- 1-Oxo-1lambda4-thiane-4-carboxylic acid13129-22-1C6H10O3S
- tert-Butyl (1-oxo-1lambda~4~-thian-4-yl)carbamate1418199-69-5C10H19NO3S
- 4-tert-Butyl-2-chloro-1lambda~4~-thian-1-one65167-65-9C9H17ClOS
- 3-Pentyl-1lambda~4~-thian-1-one62290-30-6C10H20OS
- 4-Amino-1lambda4-thian-1-one hydrochloride1158419-15-8C5H12ClNOS
- 4-Amino-4-methyl-1lambda4-thian-1-one1461706-41-1C6H13NOS
- Tetrahydro-2H-thiopyran-4-carboxaldehyde 1-oxide1383808-97-6C6H10O2S
- 2H-Thiopyran-3-amine, tetrahydro-, 1-oxide, trans-117593-49-4C5H11NOS
- 3-Bromotetrahydro-2H-thiopyran 1-oxide332041-59-5C5H9BrOS
- Tetrahydro-2H-thiopyran-4-carbonitrile 1-oxide2485012-90-4C6H9NOS
- (1S,3R)-3-Aminotetrahydro-2H-thiopyran1-oxide117593-50-7C5H11NOS
- 1-(1-Oxidotetrahydro-2H-thiopyran-4-yl)thiourea1602646-23-0C6H12N2OS2
- 2-((1-Oxidotetrahydro-2H-thiopyran-4-yl)amino)acetonitrile1597628-56-2C7H12N2OS
- Starbld0047229C5H11NOS
- 4-((Prop-2-yn-1-yloxy)amino)tetrahydro-2H-thiopyran 1-oxide1859152-04-7C8H13NO2S
- (S)-3-Amino-2-((1-oxidotetrahydro-2H-thiopyran-4-yl)amino)propanoic acidC8H16N2O3S
- 3-Amino-2-[(1-oxothian-4-yl)amino]propanoic acid1696878-14-4C8H16N2O3S
- 4-Sulfanyl-1lambda4-thian-1-one2172264-04-7C5H10OS2
- Trans-4-Aminotetrahydro-2H-thiopyran 1-oxide methanesulfonate2100857-63-2C6H15NO4S2
- 2H-Thiopyran-3-amine, tetrahydro-, 1-oxide, cis-C5H11NOS
- 4-[(3-Fluoro-2-hydroxypropyl)amino]-1lambda4-thian-1-one1850253-82-5C8H16FNO2S
- 4-Amino-4-methyl-1lambda4-thian-1-one hydrochloride2757917-11-4C6H14ClNOS
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
