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Murcko scaffold

Ring system with 2 rings and 18 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
18
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)C(=O)NC1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C(=O)NC1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Nbd-556 chemical structure, C17H24ClN3O2, CAS 333353-44-9
Nbd-556
CAS 333353-44-9C17H24ClN3O2
N~1~-(4-tert-butylphenyl)-N~2~-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide chemical structure, C21H33N3O2, CAS 496940-98-8
N~1~-(4-tert-butylphenyl)-N~2~-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide
CAS 496940-98-8C21H33N3O2
N'-(4-Propoxyphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide chemical structure, C20H31N3O3, CAS 496940-99-9
N'-(4-Propoxyphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
CAS 496940-99-9C20H31N3O3
N'-(2-Methylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide chemical structure, C18H27N3O2, CAS 500106-86-5
N'-(2-Methylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
CAS 500106-86-5C18H27N3O2
N'-(4-Methylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide chemical structure, C18H27N3O2, CAS 144217-65-2
N'-(4-Methylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
CAS 144217-65-2C18H27N3O2
N-(4-Isopropylphenyl)-N'-(2,2,6,6-tetramethyl-4-piperidyl)oxamide chemical structure, C20H31N3O2, CAS 351067-31-7
N-(4-Isopropylphenyl)-N'-(2,2,6,6-tetramethyl-4-piperidyl)oxamide
CAS 351067-31-7C20H31N3O2
Nbd-557 chemical structure, C17H24BrN3O2, CAS 333352-59-3
Nbd-557
CAS 333352-59-3C17H24BrN3O2
Ethyl 4-(2-((2-fluorophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C16H20FN3O4, CAS 1206995-36-9
Ethyl 4-(2-((2-fluorophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1206995-36-9C16H20FN3O4
Ethyl 4-(2-((2-cyanophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C17H20N4O4, CAS 1207017-81-9
Ethyl 4-(2-((2-cyanophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1207017-81-9C17H20N4O4
Ethyl 4-(2-((3,4-dimethylphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C18H25N3O4, CAS 1206991-86-7
Ethyl 4-(2-((3,4-dimethylphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1206991-86-7C18H25N3O4
Ethyl 4-(2-((2-methoxyphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C17H23N3O5, CAS 1207044-97-0
Ethyl 4-(2-((2-methoxyphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1207044-97-0C17H23N3O5
Ethyl 4-(2-((2-chlorophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C16H20ClN3O4, CAS 1207057-84-8
Ethyl 4-(2-((2-chlorophenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1207057-84-8C16H20ClN3O4
Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C17H22ClN3O4, CAS 1206995-37-0
Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1206995-37-0C17H22ClN3O4
Ethyl 4-(2-((3-chloro-4-methoxyphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C17H22ClN3O5, CAS 1207018-24-3
Ethyl 4-(2-((3-chloro-4-methoxyphenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1207018-24-3C17H22ClN3O5
Ethyl 4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)acetamido)piperidine-1-carboxylate chemical structure, C17H20F3N3O4, CAS 1206995-38-1
Ethyl 4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)acetamido)piperidine-1-carboxylate
CAS 1206995-38-1C17H20F3N3O4
Ethyl 4-(2-((2-(methylthio)phenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate chemical structure, C17H23N3O4S, CAS 1210305-22-8
Ethyl 4-(2-((2-(methylthio)phenyl)amino)-2-oxoacetamido)piperidine-1-carboxylate
CAS 1210305-22-8C17H23N3O4S
Jrc-II-191 chemical structure, C17H23ClFN3O2, CAS 1098209-30-3
Jrc-II-191
CAS 1098209-30-3C17H23ClFN3O2
N'-(1-Carbamimidoyl-4-piperidyl)-N-(4-chlorophenyl)oxamide chemical structure, C14H18ClN5O2, CAS 1349902-30-2
N'-(1-Carbamimidoyl-4-piperidyl)-N-(4-chlorophenyl)oxamide
CAS 1349902-30-2C14H18ClN5O2