CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 30 atoms

61 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
61
With full pages
8
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

3-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]triazolo[1,5-a]quinazolin-5-amine chemical structure, C22H16ClN5O2S, CAS 866340-86-5
3-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]triazolo[1,5-a]quinazolin-5-amine
CAS 866340-86-5C22H16ClN5O2S
N-[(2-Methoxyphenyl)methyl]-3-(4-methylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine chemical structure, C24H21N5O3S, CAS 866589-18-6
N-[(2-Methoxyphenyl)methyl]-3-(4-methylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine
CAS 866589-18-6C24H21N5O3S
N-[(4-Methoxyphenyl)methyl]-3-(4-methylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine chemical structure, C24H21N5O3S, CAS 866589-20-0
N-[(4-Methoxyphenyl)methyl]-3-(4-methylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine
CAS 866589-20-0C24H21N5O3S
N-[(3-Methoxyphenyl)methyl]-3-(4-propan-2-ylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine chemical structure, C26H25N5O3S, CAS 866726-90-1
N-[(3-Methoxyphenyl)methyl]-3-(4-propan-2-ylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine
CAS 866726-90-1C26H25N5O3S
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20FN5O2S, CAS 866807-74-1
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-74-1C24H20FN5O2S
N-(2-Chlorobenzyl)-3-[(2,5-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20ClN5O2S, CAS 866807-78-5
N-(2-Chlorobenzyl)-3-[(2,5-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-78-5C24H20ClN5O2S
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(2-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O3S, CAS 866807-79-6
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(2-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-79-6C25H23N5O3S
N-(4-Chlorobenzyl)-3-[(2,5-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20ClN5O2S, CAS 866807-81-0
N-(4-Chlorobenzyl)-3-[(2,5-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-81-0C24H20ClN5O2S
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O3S, CAS 866807-83-2
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-83-2C25H23N5O3S
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-methylbenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O2S, CAS 866807-85-4
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(4-methylbenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-85-4C25H23N5O2S
N-Benzyl-3-[(4-chlorophenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C22H16ClN5O2S, CAS 872197-05-2
N-Benzyl-3-[(4-chlorophenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-05-2C22H16ClN5O2S
3-(4-Chlorophenyl)sulfonyl-N-[(4-fluorophenyl)methyl]triazolo[1,5-a]quinazolin-5-amine chemical structure, C22H15ClFN5O2S, CAS 872197-07-4
3-(4-Chlorophenyl)sulfonyl-N-[(4-fluorophenyl)methyl]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-07-4C22H15ClFN5O2S
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20FN5O2S, CAS 872197-13-2
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-13-2C24H20FN5O2S
N-(2-Chlorobenzyl)-3-[(2,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20ClN5O2S, CAS 872197-18-7
N-(2-Chlorobenzyl)-3-[(2,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-18-7C24H20ClN5O2S
N-(4-Chlorobenzyl)-3-[(2,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20ClN5O2S, CAS 872197-19-8
N-(4-Chlorobenzyl)-3-[(2,4-dimethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-19-8C24H20ClN5O2S
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(4-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O3S, CAS 872197-21-2
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(4-methoxybenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-21-2C25H23N5O3S
3-(2,4-Dimethylphenyl)sulfonyl-N-[(4-methylphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O2S, CAS 872197-23-4
3-(2,4-Dimethylphenyl)sulfonyl-N-[(4-methylphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-23-4C25H23N5O2S
N-Benzyl-3-(4-ethylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine chemical structure, C24H21N5O2S, CAS 872200-01-6
N-Benzyl-3-(4-ethylphenyl)sulfonyltriazolo[1,5-a]quinazolin-5-amine
CAS 872200-01-6C24H21N5O2S
3-[(4-Ethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20FN5O2S, CAS 872200-02-7
3-[(4-Ethylphenyl)sulfonyl]-N-(4-fluorobenzyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872200-02-7C24H20FN5O2S
N-(4-Chlorobenzyl)-3-[(4-ethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C24H20ClN5O2S, CAS 872200-04-9
N-(4-Chlorobenzyl)-3-[(4-ethylphenyl)sulfonyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872200-04-9C24H20ClN5O2S
3-(4-Ethylphenyl)sulfonyl-N-[(4-methoxyphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O3S, CAS 872200-05-0
3-(4-Ethylphenyl)sulfonyl-N-[(4-methoxyphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine
CAS 872200-05-0C25H23N5O3S
3-(3,4-Dimethylphenyl)sulfonyl-N-[(3-methoxyphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O3S, CAS 872209-17-1
3-(3,4-Dimethylphenyl)sulfonyl-N-[(3-methoxyphenyl)methyl]triazolo[1,5-a]quinazolin-5-amine
CAS 872209-17-1C25H23N5O3S
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(1-phenylethyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O2S, CAS 866807-75-2
3-[(2,5-Dimethylphenyl)sulfonyl]-N-(1-phenylethyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 866807-75-2C25H23N5O2S
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(1-phenylethyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine chemical structure, C25H23N5O2S, CAS 872197-16-5
3-[(2,4-Dimethylphenyl)sulfonyl]-N-(1-phenylethyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
CAS 872197-16-5C25H23N5O2S