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Murcko scaffold

Ring system with 4 rings and 24 atoms

141 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
141
With full pages
23
Scaffold SMILES

O=C(Nc1cccc(-c2nc3ncccc3o2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccc(-c2nc3ncccc3o2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 141 chemicals

3,4-Dimethoxy-N-(2-methyl-3-oxazolo[4,5-b]pyridin-2-yl-phenyl)-benzamide chemical structure, C22H19N3O4, CAS 330178-22-8
3,4-Dimethoxy-N-(2-methyl-3-oxazolo[4,5-b]pyridin-2-yl-phenyl)-benzamide
CAS 330178-22-8C22H19N3O4
2-Fluoro-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H12FN3O2, CAS 431917-21-4
2-Fluoro-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 431917-21-4C19H12FN3O2
2-Methyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O2, CAS 380156-11-6
2-Methyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 380156-11-6C20H15N3O2
2-Methoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O3, CAS 381175-26-4
2-Methoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 381175-26-4C20H15N3O3
4-Methoxy-N-(3-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide chemical structure, C20H15N3O3, CAS 380573-48-8
4-Methoxy-N-(3-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide
CAS 380573-48-8C20H15N3O3
4-Fluoro-N-(2-methyl-5-(oxazolo[4,5-b]pyridin-2-yl)phenyl)benzamide chemical structure, C20H14FN3O2, CAS 303131-51-3
4-Fluoro-N-(2-methyl-5-(oxazolo[4,5-b]pyridin-2-yl)phenyl)benzamide
CAS 303131-51-3C20H14FN3O2
2-Fluoro-N-(2-methyl-5-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide chemical structure, C20H14FN3O2, CAS 292058-19-6
2-Fluoro-N-(2-methyl-5-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide
CAS 292058-19-6C20H14FN3O2
4-Methyl-N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 332151-17-4
4-Methyl-N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 332151-17-4C21H17N3O2
2-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 312633-05-9
2-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 312633-05-9C21H17N3O2
3-Methoxy-N-(3-(oxazolo[4,5-b]pyridin-2-yl)phenyl)benzamide chemical structure, C20H15N3O3, CAS 314054-29-0
3-Methoxy-N-(3-(oxazolo[4,5-b]pyridin-2-yl)phenyl)benzamide
CAS 314054-29-0C20H15N3O3
N-[2-Methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O2, CAS 328907-89-7
N-[2-Methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 328907-89-7C20H15N3O2
3-Methyl-N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 5756-79-6
3-Methyl-N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 5756-79-6C21H17N3O2
3-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 380869-18-1
3-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 380869-18-1C21H17N3O2
N-[2-Methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O2, CAS 303131-50-2
N-[2-Methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 303131-50-2C20H15N3O2
4-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 380875-31-0
4-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 380875-31-0C21H17N3O2
2,4-Dimethyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 673444-38-7
2,4-Dimethyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 673444-38-7C21H17N3O2
3,4,5-Triethoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C25H25N3O5, CAS 309737-99-3
3,4,5-Triethoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 309737-99-3C25H25N3O5
4-tert-Butyl-N-(4-chloro-3-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide chemical structure, C23H20ClN3O2, CAS 353766-21-9
4-tert-Butyl-N-(4-chloro-3-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide
CAS 353766-21-9C23H20ClN3O2
3,5-Dichloro-4-methoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H13Cl2N3O3, CAS 353500-34-2
3,5-Dichloro-4-methoxy-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 353500-34-2C20H13Cl2N3O3
N-[2-Chloro-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3,5-dimethoxybenzamide chemical structure, C21H16ClN3O4, CAS 443321-60-6
N-[2-Chloro-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3,5-dimethoxybenzamide
CAS 443321-60-6C21H16ClN3O4
N-[2-Chloro-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-ethoxybenzamide chemical structure, C21H16ClN3O3, CAS 347338-75-4
N-[2-Chloro-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-ethoxybenzamide
CAS 347338-75-4C21H16ClN3O3
3-Chloro-4-methyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H14ClN3O2, CAS 380584-12-3
3-Chloro-4-methyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 380584-12-3C20H14ClN3O2
3,5-Dimethoxy-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C22H19N3O4, CAS 431910-84-8
3,5-Dimethoxy-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 431910-84-8C22H19N3O4
3-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-4-nitrobenzamide chemical structure, C21H16N4O4, CAS 303131-45-5
3-Methyl-N-[2-methyl-5-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-4-nitrobenzamide
CAS 303131-45-5C21H16N4O4