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Murcko scaffold

Ring system with 4 rings and 24 atoms

118 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
118
With full pages
9
Scaffold SMILES

O=C(Nc1cccc(-c2cn3cccnc3n2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccc(-c2cn3cccnc3n2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 118 chemicals

2,4-Dichloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide chemical structure, C19H12Cl2N4O, CAS 861210-38-0
2,4-Dichloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide
CAS 861210-38-0C19H12Cl2N4O
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3-nitrobenzamide chemical structure, C19H13N5O3, CAS 864935-62-6
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3-nitrobenzamide
CAS 864935-62-6C19H13N5O3
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3,4,5-trimethoxybenzamide chemical structure, C22H20N4O4, CAS 863020-18-2
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3,4,5-trimethoxybenzamide
CAS 863020-18-2C22H20N4O4
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3,5-dimethylbenzamide chemical structure, C21H18N4O, CAS 863020-08-0
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-3,5-dimethylbenzamide
CAS 863020-08-0C21H18N4O
N-(5-Imidazo[1,2-a]pyrimidin-2-yl-2-methoxyphenyl)benzamide chemical structure, C20H16N4O2, CAS 847387-98-8
N-(5-Imidazo[1,2-a]pyrimidin-2-yl-2-methoxyphenyl)benzamide
CAS 847387-98-8C20H16N4O2
N-(5-{Imidazo[1,2-A]pyrimidin-2-YL}-2-methylphenyl)benzamide chemical structure, C20H16N4O, CAS 847387-73-9
N-(5-{Imidazo[1,2-A]pyrimidin-2-YL}-2-methylphenyl)benzamide
CAS 847387-73-9C20H16N4O
3-Chloro-N-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide chemical structure, C20H15ClN4O, CAS 862811-73-2
3-Chloro-N-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide
CAS 862811-73-2C20H15ClN4O
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-4-methylbenzamide chemical structure, C20H16N4O, CAS 847387-53-5
N-(3-{Imidazo[1,2-A]pyrimidin-2-YL}phenyl)-4-methylbenzamide
CAS 847387-53-5C20H16N4O
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-2,3-dimethoxybenzamide chemical structure, C21H18N4O3, CAS 863020-14-8
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-2,3-dimethoxybenzamide
CAS 863020-14-8C21H18N4O3
2-Fluoro-N-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide chemical structure, C20H15FN4O, CAS 862811-70-9
2-Fluoro-N-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide
CAS 862811-70-9C20H15FN4O
N-(3-(Imidazo[1,2-a]pyrimidin-2-yl)phenyl)-2-(trifluoromethyl)benzamide chemical structure, C20H13F3N4O, CAS 863020-29-5
N-(3-(Imidazo[1,2-a]pyrimidin-2-yl)phenyl)-2-(trifluoromethyl)benzamide
CAS 863020-29-5C20H13F3N4O
4-(tert-Butyl)-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide chemical structure, C23H22N4O, CAS 863020-10-4
4-(tert-Butyl)-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide
CAS 863020-10-4C23H22N4O
N-(3-(Imidazo[1,2-a]pyrimidin-2-yl)phenyl)-2-methylbenzamide chemical structure, C20H16N4O, CAS 847387-51-3
N-(3-(Imidazo[1,2-a]pyrimidin-2-yl)phenyl)-2-methylbenzamide
CAS 847387-51-3C20H16N4O
N-(3-{Imidazo[1,2-a]pyrimidin-2-yl}phenyl)-4-methoxybenzamide chemical structure, C20H16N4O2, CAS 847387-55-7
N-(3-{Imidazo[1,2-a]pyrimidin-2-yl}phenyl)-4-methoxybenzamide
CAS 847387-55-7C20H16N4O2
2-Ethoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide chemical structure, C21H18N4O2, CAS 863020-11-5
2-Ethoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide
CAS 863020-11-5C21H18N4O2
4-Ethoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide chemical structure, C21H18N4O2, CAS 863020-12-6
4-Ethoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide
CAS 863020-12-6C21H18N4O2
4-Butoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide chemical structure, C23H22N4O2, CAS 863020-13-7
4-Butoxy-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)benzamide
CAS 863020-13-7C23H22N4O2
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3,4-dimethoxybenzamide chemical structure, C21H18N4O3, CAS 847387-56-8
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3,4-dimethoxybenzamide
CAS 847387-56-8C21H18N4O3
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3,5-dimethoxybenzamide chemical structure, C21H18N4O3, CAS 863020-15-9
N-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3,5-dimethoxybenzamide
CAS 863020-15-9C21H18N4O3
3,4-Diethoxy-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide chemical structure, C23H22N4O3, CAS 863020-17-1
3,4-Diethoxy-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide
CAS 863020-17-1C23H22N4O3
3-Fluoro-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide chemical structure, C19H13FN4O, CAS 863020-20-6
3-Fluoro-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide
CAS 863020-20-6C19H13FN4O
2-Chloro-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide chemical structure, C19H13ClN4O, CAS 863020-21-7
2-Chloro-N-(3-(imidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide
CAS 863020-21-7C19H13ClN4O
3-Chloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide chemical structure, C19H13ClN4O, CAS 863020-22-8
3-Chloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide
CAS 863020-22-8C19H13ClN4O
4-Chloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide chemical structure, C19H13ClN4O, CAS 847387-59-1
4-Chloro-N-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide
CAS 847387-59-1C19H13ClN4O