Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 2 rings and 13 atoms

42 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 42
With full pages: 4

Scaffold SMILES

O=c1[nH]ccnc1N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1[nH]ccnc1N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

3-(3-Aminopiperidin-1-yl)-1-ethylpyrazin-2(1H)-one chemical structure, C11H18N4O, CAS 1339425-54-5

3-(3-Aminopiperidin-1-yl)-1-ethylpyrazin-2(1H)-one

CAS 1339425-54-5C₁₁H₁₈N₄O

3-(4-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one chemical structure, C10H16N4O, CAS 1406172-40-4

3-(4-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one

CAS 1406172-40-4C₁₀H₁₆N₄O

1-(4-Methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1273894-42-0

1-(4-Methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-3-carboxylic acid

CAS 1273894-42-0C₁₁H₁₅N₃O₃

3-(4-Aminopiperidin-1-yl)-1-ethyl-1,2-dihydropyrazin-2-one chemical structure, C11H18N4O, CAS 1342376-93-5

3-(4-Aminopiperidin-1-yl)-1-ethyl-1,2-dihydropyrazin-2-one

CAS 1342376-93-5C₁₁H₁₈N₄O

3-(3-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one chemical structure, C10H16N4O, CAS 1342735-58-3

3-(3-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one

CAS 1342735-58-3C₁₀H₁₆N₄O

3-(4-(Aminomethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C11H18N4O, CAS 1340231-41-5

3-(4-(Aminomethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1340231-41-5C₁₁H₁₈N₄O

3-(3-(Aminomethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C11H18N4O, CAS 1378456-39-3

3-(3-(Aminomethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1378456-39-3C₁₁H₁₈N₄O

1-(4-Methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-4-carboxylic acid chemical structure, C11H15N3O3, CAS 1275219-59-4

1-(4-Methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-4-carboxylic acid

CAS 1275219-59-4C₁₁H₁₅N₃O₃

3-(3-Hydroxypiperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C10H15N3O2, CAS 1341563-84-5

3-(3-Hydroxypiperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1341563-84-5C₁₀H₁₅N₃O₂

3-(4-Hydroxypiperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C10H15N3O2, CAS 1343376-22-6

3-(4-Hydroxypiperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1343376-22-6C₁₀H₁₅N₃O₂

3-(3-(Hydroxymethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C11H17N3O2, CAS 1344041-15-1

3-(3-(Hydroxymethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1344041-15-1C₁₁H₁₇N₃O₂

3-(4-(Hydroxymethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one chemical structure, C11H17N3O2, CAS 1339172-75-6

3-(4-(Hydroxymethyl)piperidin-1-yl)-1-methylpyrazin-2(1H)-one

CAS 1339172-75-6C₁₁H₁₇N₃O₂

3-(3-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one dihydrochloride chemical structure, C10H18Cl2N4O, CAS 1803599-94-1

3-(3-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one dihydrochloride

CAS 1803599-94-1C₁₀H₁₈Cl₂N₄O

3-(3-Aminopiperidin-1-yl)-1,2-dihydropyrazin-2-one dihydrochloride chemical structure, C9H16Cl2N4O, CAS 1798756-28-1

3-(3-Aminopiperidin-1-yl)-1,2-dihydropyrazin-2-one dihydrochloride

CAS 1798756-28-1C₉H₁₆Cl₂N₄O

3-(3-Aminopiperidin-1-yl)pyrazin-2(1H)-one chemical structure, C9H14N4O, CAS 1597062-59-3

3-(3-Aminopiperidin-1-yl)pyrazin-2(1H)-one

CAS 1597062-59-3C₉H₁₄N₄O

3-(4-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one dihydrochloride chemical structure, C10H18Cl2N4O, CAS 1803598-11-9

3-(4-Aminopiperidin-1-yl)-1-methyl-1,2-dihydropyrazin-2-one dihydrochloride

CAS 1803598-11-9C₁₀H₁₈Cl₂N₄O

tert-Butyl [1-(3-oxo-3,4-dihydropyrazin-2-yl)piperidin-3-yl]carbamate chemical structure, C14H22N4O3, CAS 1923237-08-4

tert-Butyl [1-(3-oxo-3,4-dihydropyrazin-2-yl)piperidin-3-yl]carbamate

CAS 1923237-08-4C₁₄H₂₂N₄O₃

tert-Butyl [1-(4-methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidin-3-yl]carbamate chemical structure, C15H24N4O3, CAS 1993243-37-0

tert-Butyl [1-(4-methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidin-3-yl]carbamate

CAS 1993243-37-0C₁₅H₂₄N₄O₃

tert-Butyl [1-(4-methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidin-4-yl]carbamate chemical structure, C15H24N4O3, CAS 1987263-34-2

tert-Butyl [1-(4-methyl-3-oxo-3,4-dihydropyrazin-2-yl)piperidin-4-yl]carbamate

CAS 1987263-34-2C₁₅H₂₄N₄O₃

3-(3-Aminopiperidin-1-yl)pyrazin-2(1H)-one hydrochloride chemical structure, C9H15ClN4O, CAS 1638612-92-6

3-(3-Aminopiperidin-1-yl)pyrazin-2(1H)-one hydrochloride

CAS 1638612-92-6C₉H₁₅ClN₄O

3-(3-Aminopiperidin-1-yl)-1-methylpyrazin-2(1H)-one hydrochloride chemical structure, C10H17ClN4O, CAS 1638612-52-8

3-(3-Aminopiperidin-1-yl)-1-methylpyrazin-2(1H)-one hydrochloride

CAS 1638612-52-8C₁₀H₁₇ClN₄O

3-(4-Aminopiperidin-1-yl)-1-methylpyrazin-2(1H)-one hydrochloride chemical structure, C10H17ClN4O, CAS 1638612-80-2

3-(4-Aminopiperidin-1-yl)-1-methylpyrazin-2(1H)-one hydrochloride

CAS 1638612-80-2C₁₀H₁₇ClN₄O

Ethyl 1-(3-oxo-3,4-dihydropyrazin-2-yl)piperidine-3-carboxylate chemical structure, C12H17N3O3, CAS 1778895-45-6

Ethyl 1-(3-oxo-3,4-dihydropyrazin-2-yl)piperidine-3-carboxylate

CAS 1778895-45-6C₁₂H₁₇N₃O₃

3-(4-Aminopiperidin-1-yl)pyrazin-2(1H)-one chemical structure, C9H14N4O, CAS 1601735-36-7

3-(4-Aminopiperidin-1-yl)pyrazin-2(1H)-one

CAS 1601735-36-7C₉H₁₄N₄O