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Murcko scaffold

2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)- scaffold

12 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
12
With full pages
3
Scaffold SMILES

O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)- page
Murcko scaffold O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Domperidone chemical structure, C22H24ClN5O2, CAS 57808-66-9
Domperidone
CAS 57808-66-9C22H24ClN5O2
Flumeridone chemical structure, C22H23ClFN5O2, CAS 75444-64-3
Flumeridone
CAS 75444-64-3C22H23ClFN5O2
2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-5-hydroxy-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro- chemical structure, C22H24ClN5O3, CAS 82294-72-2
2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-5-hydroxy-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-
CAS 82294-72-2C22H24ClN5O3
2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-, (Z)-2-butenedioate (1:1) chemical structure, C26H28ClN5O6, CAS 99497-03-7
2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-, (Z)-2-butenedioate (1:1)
CAS 99497-03-7C26H28ClN5O6
2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)- chemical structure, C22H25N5O2, CAS 62781-23-1
2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)-
CAS 62781-23-1C22H25N5O2
Domperidone (monomaleate) chemical structure, C26H28ClN5O6
Domperidone (monomaleate)
C26H28ClN5O6
Touristil chemical structure, C48H52ClN7O2, CAS 108116-23-0
Touristil
CAS 108116-23-0C48H52ClN7O2
Domperidone maleate chemical structure, C26H28ClN5O6, CAS 83898-65-1
Domperidone maleate
CAS 83898-65-1C26H28ClN5O6
5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one (2Z)-but-2-enedioate chemical structure, C26H28ClN5O6
5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one (2Z)-but-2-enedioate
C26H28ClN5O6
Domperidone impurity C chemical structure, C22H24ClN5O3, CAS 118435-03-3
Domperidone impurity C
CAS 118435-03-3C22H24ClN5O3
Domperidone-d6 chemical structure, C22H24ClN5O2, CAS 1329614-18-7
Domperidone-d6
CAS 1329614-18-7C22H24ClN5O2
Deudomperidone chemical structure, C22H24ClN5O2, CAS 2121525-08-2
Deudomperidone
CAS 2121525-08-2C22H24ClN5O2