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Murcko scaffold

Ring system with 5 rings and 27 atoms

168 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
168
With full pages
28
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCc2ccccc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCc2ccccc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 168 chemicals

Fmoc-L-Tic-OH chemical structure, C25H21NO4, CAS 136030-33-6
Fmoc-L-Tic-OH
CAS 136030-33-6C25H21NO4
(3R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C25H21NO4, CAS 130309-33-0
(3R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 130309-33-0C25H21NO4
(3S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C25H21NO5, CAS 178432-49-0
(3S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 178432-49-0C25H21NO5
(3R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C25H21NO5, CAS 178432-50-3
(3R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 178432-50-3C25H21NO5
(1R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid chemical structure, C25H21NO4, CAS 204317-98-6
(1R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
CAS 204317-98-6C25H21NO4
2-((3S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid chemical structure, C26H23NO4, CAS 270062-99-2
2-((3S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid
CAS 270062-99-2C26H23NO4
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C25H21NO4, CAS 171859-74-8
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 171859-74-8C25H21NO4
2-(9H-Fluoren-9-ylmethoxycarbonyl)-7-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid chemical structure, C25H21NO5, CAS 1214066-60-0
2-(9H-Fluoren-9-ylmethoxycarbonyl)-7-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
CAS 1214066-60-0C25H21NO5
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid chemical structure, C25H21NO4, CAS 182161-83-7
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
CAS 182161-83-7C25H21NO4
2-((3R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid chemical structure, C26H23NO4, CAS 332064-67-2
2-((3R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid
CAS 332064-67-2C26H23NO4
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid chemical structure, C25H21NO4, CAS 204317-99-7
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
CAS 204317-99-7C25H21NO4
2-(2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid chemical structure, C26H23NO4, CAS 540483-55-4
2-(2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid
CAS 540483-55-4C26H23NO4
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid chemical structure, C28H27NO6, CAS 282524-91-8
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid
CAS 282524-91-8C28H27NO6
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid chemical structure, C26H23NO5, CAS 1233025-96-1
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
CAS 1233025-96-1C26H23NO5
2-(2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid chemical structure, C26H23NO4, CAS 415963-69-8
2-(2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid
CAS 415963-69-8C26H23NO4
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid chemical structure, C25H21NO4, CAS 1199776-90-3
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
CAS 1199776-90-3C25H21NO4
(S)-3-Aminomethyl-2-fmoc-1,2,3,4-tetrahydro-isoquinoline hydrochloride chemical structure, C25H25ClN2O2, CAS 1187932-12-2
(S)-3-Aminomethyl-2-fmoc-1,2,3,4-tetrahydro-isoquinoline hydrochloride
CAS 1187932-12-2C25H25ClN2O2
(S)-3-Aminomethyl-2-fmoc-1,2,3,4-tetrahydro-isoquinoline chemical structure, C25H24N2O2, CAS 1187933-38-5
(S)-3-Aminomethyl-2-fmoc-1,2,3,4-tetrahydro-isoquinoline
CAS 1187933-38-5C25H24N2O2
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid chemical structure, C25H21NO4, CAS 1556628-22-8
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid
CAS 1556628-22-8C25H21NO4
3-Aminomethyl-2-Fmoc-1,2,3,4-tetrahydro-isoquinoline chemical structure, C25H24N2O2, CAS 1187933-39-6
3-Aminomethyl-2-Fmoc-1,2,3,4-tetrahydro-isoquinoline
CAS 1187933-39-6C25H24N2O2
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid chemical structure, C25H21NO4, CAS 1565609-39-3
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid
CAS 1565609-39-3C25H21NO4
(9H-Fluoren-9-yl)methyl 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylate chemical structure, C24H21NO3, CAS 1657738-53-8
(9H-Fluoren-9-yl)methyl 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
CAS 1657738-53-8C24H21NO3
(9H-Fluoren-9-yl)methyl 3-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate hydrochloride chemical structure, C25H25ClN2O2, CAS 1187932-19-9
(9H-Fluoren-9-yl)methyl 3-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate hydrochloride
CAS 1187932-19-9C25H25ClN2O2
2-[(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]acetic acid chemical structure, C26H23NO4, CAS 596827-28-0
2-[(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]acetic acid
CAS 596827-28-0C26H23NO4