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Murcko scaffold

4-Phenyl-3,4-dihydro-1H-benzo[h]quinolin-2-one scaffold

59 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
59
With full pages
4
Scaffold SMILES

O=C1CC(c2ccccc2)c2ccc3ccccc3c2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-3,4-dihydro-1H-benzo[h]quinolin-2-one page
Murcko scaffold O=C1CC(c2ccccc2)c2ccc3ccccc3c2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

4-(2-Fluorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14FNO, CAS 303139-25-5
4-(2-Fluorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 303139-25-5C19H14FNO
4-(4-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14INO, CAS 301321-41-5
4-(4-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301321-41-5C19H14INO
4-(2-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14INO, CAS 301321-35-7
4-(2-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301321-35-7C19H14INO
4-(3-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14INO, CAS 301319-28-8
4-(3-Iodophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301319-28-8C19H14INO
4-Phenyl-3,4-dihydro-1H-benzo[h]quinolin-2-one chemical structure, C19H15NO, CAS 64257-24-5
4-Phenyl-3,4-dihydro-1H-benzo[h]quinolin-2-one
CAS 64257-24-5C19H15NO
4-(4-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14N2O3, CAS 64257-36-9
4-(4-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 64257-36-9C19H14N2O3
4-(4-Chlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14ClNO, CAS 5473-83-6
4-(4-Chlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 5473-83-6C19H14ClNO
4-(2-Butoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C23H23NO2, CAS 314046-68-9
4-(2-Butoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 314046-68-9C23H23NO2
4-(2-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14N2O3, CAS 64257-34-7
4-(2-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 64257-34-7C19H14N2O3
4-(2-Trifluoromethyl-phenyl)-3,4-dihydro-1H-benzo[h]quinolin-2-one chemical structure, C20H14F3NO, CAS 301319-77-7
4-(2-Trifluoromethyl-phenyl)-3,4-dihydro-1H-benzo[h]quinolin-2-one
CAS 301319-77-7C20H14F3NO
4-(3-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14N2O3, CAS 64257-35-8
4-(3-Nitrophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 64257-35-8C19H14N2O3
4-(2,3-Dichlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H13Cl2NO, CAS 301319-74-4
4-(2,3-Dichlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301319-74-4C19H13Cl2NO
4-(3,4,5-Trimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C22H21NO4, CAS 64257-29-0
4-(3,4,5-Trimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 64257-29-0C22H21NO4
4-(3-Bromophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14BrNO, CAS 301319-78-8
4-(3-Bromophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301319-78-8C19H14BrNO
4-(2,5-Dimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C21H19NO3, CAS 5613-92-3
4-(2,5-Dimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 5613-92-3C21H19NO3
4-(4-Methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C20H17NO2, CAS 64257-25-6
4-(4-Methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 64257-25-6C20H17NO2
4-(2-Chlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14ClNO, CAS 301319-25-5
4-(2-Chlorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301319-25-5C19H14ClNO
4-(2-Methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C20H17NO2, CAS 301321-42-6
4-(2-Methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301321-42-6C20H17NO2
4-(4-Hydroxy-3-methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C20H17NO3, CAS 331840-48-3
4-(4-Hydroxy-3-methoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 331840-48-3C20H17NO3
4-(3-Fluorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C19H14FNO, CAS 301321-43-7
4-(3-Fluorophenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 301321-43-7C19H14FNO
4-(3-Ethoxy-4-hydroxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C21H19NO3, CAS 326903-20-2
4-(3-Ethoxy-4-hydroxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 326903-20-2C21H19NO3
RefChem:381294 chemical structure, C22H21NO4, CAS 5749-92-8
RefChem:381294
CAS 5749-92-8C22H21NO4
4-(4-Isopropylphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C22H21NO, CAS 329066-05-9
4-(4-Isopropylphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 329066-05-9C22H21NO
4-(2-Bromo-4,5-dimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one chemical structure, C21H18BrNO3, CAS 329065-99-8
4-(2-Bromo-4,5-dimethoxyphenyl)-3,4-dihydrobenzo[h]quinolin-2(1H)-one
CAS 329065-99-8C21H18BrNO3