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Murcko scaffold

4-Phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one scaffold

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
5
With full pages
1
Scaffold SMILES

O=C1NC2=C(CCc3ccccc32)C(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one page
Murcko scaffold O=C1NC2=C(CCc3ccccc32)C(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

4-(3-Methoxyphenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one chemical structure, C19H18N2O2, CAS 724740-80-1
4-(3-Methoxyphenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one
CAS 724740-80-1C19H18N2O2
4-(4-Methoxy-3-nitrophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one chemical structure, C19H17N3O4, CAS 674815-69-1
4-(4-Methoxy-3-nitrophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one
CAS 674815-69-1C19H17N3O4
Benzo[h]quinazolin-2(1H)-one, 4-(4-chlorophenyl)-3,4,5,6-tetrahydro- chemical structure, C18H15ClN2O, CAS 114857-82-8
Benzo[h]quinazolin-2(1H)-one, 4-(4-chlorophenyl)-3,4,5,6-tetrahydro-
CAS 114857-82-8C18H15ClN2O
4-Phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one chemical structure, C18H16N2O, CAS 3977-31-9
4-Phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one
CAS 3977-31-9C18H16N2O
3,4,5,6-Tetrahydro-8-methoxy-4-(4-methylphenyl)benzo[h]quinazolin-2(1H)-one chemical structure, C20H20N2O2, CAS 1365391-22-5
3,4,5,6-Tetrahydro-8-methoxy-4-(4-methylphenyl)benzo[h]quinazolin-2(1H)-one
CAS 1365391-22-5C20H20N2O2