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Murcko scaffold

Pyrrolidine, 1-(1,3-benzodioxol-5-ylcarbonyl)- scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
27
With full pages
2
Scaffold SMILES

O=C(c1ccc2c(c1)OCO2)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrrolidine, 1-(1,3-benzodioxol-5-ylcarbonyl)- page
Murcko scaffold O=C(c1ccc2c(c1)OCO2)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

Diethyl 5-ethoxy-3-methyl-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate chemical structure, C21H26N2O10, CAS 66709-23-7
Diethyl 5-ethoxy-3-methyl-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate
CAS 66709-23-7C21H26N2O10
Diethyl 5-hydroxy-3-methyl-1-(6-nitro-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate chemical structure, C19H22N2O10, CAS 66709-20-4
Diethyl 5-hydroxy-3-methyl-1-(6-nitro-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate
CAS 66709-20-4C19H22N2O10
Diethyl 5-hydroxy-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate chemical structure, C18H20N2O10, CAS 66709-19-1
Diethyl 5-hydroxy-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate
CAS 66709-19-1C18H20N2O10
Diethyl 5-ethoxy-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate chemical structure, C20H24N2O10, CAS 66709-22-6
Diethyl 5-ethoxy-1-(6-nitro-2H-1,3-benzodioxole-5-carbonyl)pyrrolidine-2,2-dicarboxylate
CAS 66709-22-6C20H24N2O10
Pyrrolidine, 1-(1,3-benzodioxol-5-ylcarbonyl)- chemical structure, C12H13NO3, CAS 64654-10-0
Pyrrolidine, 1-(1,3-benzodioxol-5-ylcarbonyl)-
CAS 64654-10-0C12H13NO3
1-(1,3-Dioxaindane-5-carbonyl)pyrrolidine-2-carboxylic acid chemical structure, C13H13NO5, CAS 142962-04-7
1-(1,3-Dioxaindane-5-carbonyl)pyrrolidine-2-carboxylic acid
CAS 142962-04-7C13H13NO5
1-(2H-1,3-Benzodioxole-5-carbonyl)pyrrolidin-3-ol chemical structure, C12H13NO4, CAS 1281354-09-3
1-(2H-1,3-Benzodioxole-5-carbonyl)pyrrolidin-3-ol
CAS 1281354-09-3C12H13NO4
(4R)-1-(2H-1,3-Benzodioxole-5-carbonyl)-4-hydroxy-L-proline chemical structure, C13H13NO6, CAS 142962-05-8
(4R)-1-(2H-1,3-Benzodioxole-5-carbonyl)-4-hydroxy-L-proline
CAS 142962-05-8C13H13NO6
Benzo[d][1,3]dioxol-5-yl(2-(hydroxymethyl)pyrrolidin-1-yl)methanone chemical structure, C13H15NO4, CAS 1176751-11-3
Benzo[d][1,3]dioxol-5-yl(2-(hydroxymethyl)pyrrolidin-1-yl)methanone
CAS 1176751-11-3C13H15NO4
1-(2H-1,3-Benzodioxole-5-carbonyl)pyrrolidin-3-amine chemical structure, C12H14N2O3, CAS 1284834-61-2
1-(2H-1,3-Benzodioxole-5-carbonyl)pyrrolidin-3-amine
CAS 1284834-61-2C12H14N2O3
Benzo[d][1,3]dioxol-5-yl(3-(hydroxymethyl)pyrrolidin-1-yl)methanone chemical structure, C13H15NO4, CAS 1420981-31-2
Benzo[d][1,3]dioxol-5-yl(3-(hydroxymethyl)pyrrolidin-1-yl)methanone
CAS 1420981-31-2C13H15NO4
(R)-Benzo[d][1,3]dioxol-5-yl(3-hydroxypyrrolidin-1-yl)methanone chemical structure, C12H13NO4, CAS 1421019-74-0
(R)-Benzo[d][1,3]dioxol-5-yl(3-hydroxypyrrolidin-1-yl)methanone
CAS 1421019-74-0C12H13NO4
6-(Pyrrolidine-1-carbonyl)-2H-1,3-benzodioxole-5-carbaldehyde chemical structure, C13H13NO4, CAS 62869-58-3
6-(Pyrrolidine-1-carbonyl)-2H-1,3-benzodioxole-5-carbaldehyde
CAS 62869-58-3C13H13NO4
(R)-tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate chemical structure, C17H22N2O5, CAS 1421027-77-1
(R)-tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate
CAS 1421027-77-1C17H22N2O5
(S)-tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate chemical structure, C17H22N2O5, CAS 1421042-17-2
(S)-tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate
CAS 1421042-17-2C17H22N2O5
tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate chemical structure, C17H22N2O5, CAS 1420867-87-3
tert-Butyl (1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)carbamate
CAS 1420867-87-3C17H22N2O5
tert-Butyl ((1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-2-yl)methyl)carbamate chemical structure, C18H24N2O5, CAS 1420822-36-1
tert-Butyl ((1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-2-yl)methyl)carbamate
CAS 1420822-36-1C18H24N2O5
tert-Butyl ((1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)methyl)carbamate chemical structure, C18H24N2O5, CAS 1420867-92-0
tert-Butyl ((1-(benzo[d][1,3]dioxole-5-carbonyl)pyrrolidin-3-yl)methyl)carbamate
CAS 1420867-92-0C18H24N2O5
(R)-(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride chemical structure, C12H15ClN2O3, CAS 1421020-82-7
(R)-(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
CAS 1421020-82-7C12H15ClN2O3
(S)-(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride chemical structure, C12H15ClN2O3, CAS 1421012-21-6
(S)-(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
CAS 1421012-21-6C12H15ClN2O3
(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride chemical structure, C12H15ClN2O3, CAS 1420868-18-3
(3-Aminopyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
CAS 1420868-18-3C12H15ClN2O3
(2-(Aminomethyl)pyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride chemical structure, C13H17ClN2O3, CAS 1420901-50-3
(2-(Aminomethyl)pyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
CAS 1420901-50-3C13H17ClN2O3
(3-(Aminomethyl)pyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride chemical structure, C13H17ClN2O3, CAS 1420826-19-2
(3-(Aminomethyl)pyrrolidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
CAS 1420826-19-2C13H17ClN2O3
(S)-Benzo[d][1,3]dioxol-5-yl(3-hydroxypyrrolidin-1-yl)methanone chemical structure, C12H13NO4, CAS 1421032-52-1
(S)-Benzo[d][1,3]dioxol-5-yl(3-hydroxypyrrolidin-1-yl)methanone
CAS 1421032-52-1C12H13NO4