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Murcko scaffold

5-(Benzo[d][1,3]dioxol-5-ylmethylene)thiazolidine-2,4-dione scaffold

24 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 24
With full pages: 8

Scaffold SMILES

O=C1NC(=O)C(=Cc2ccc3c(c2)OCO3)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-(Benzo[d][1,3]dioxol-5-ylmethylene)thiazolidine-2,4-dione page

Murcko scaffold O=C1NC(=O)C(=Cc2ccc3c(c2)OCO3)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

5-(Benzo[d][1,3]dioxol-5-ylmethylene)thiazolidine-2,4-dione chemical structure, C11H7NO4S

5-(Benzo[d][1,3]dioxol-5-ylmethylene)thiazolidine-2,4-dione

C₁₁H₇NO₄S

3-(2-Aminoethyl)-5-[(1,3-dioxaindan-5-yl)methylidene]-1,3-thiazolidine-2,4-dione chemical structure, C13H12N2O4S, CAS 350509-85-2

3-(2-Aminoethyl)-5-[(1,3-dioxaindan-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

CAS 350509-85-2C₁₃H₁₂N₂O₄S

(E)-5-((6-Bromobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione chemical structure, C11H6BrNO4S, CAS 769087-73-2

(E)-5-((6-Bromobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione

CAS 769087-73-2C₁₁H₆BrNO₄S

2,4-Thiazolidinedione, 5-[(6-bromo-1,3-benzodioxol-5-yl)methylene]-, (Z)- chemical structure, C11H6BrNO4S, CAS 58215-52-4

2,4-Thiazolidinedione, 5-[(6-bromo-1,3-benzodioxol-5-yl)methylene]-, (Z)-

CAS 58215-52-4C₁₁H₆BrNO₄S

(Z)-2-(5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2,4-dioxothiazolidin-3-yl)acetic acid chemical structure, C13H9NO6S, CAS 178881-18-0

(Z)-2-(5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2,4-dioxothiazolidin-3-yl)acetic acid

CAS 178881-18-0C₁₃H₉NO₆S

2,4-Thiazolidinedione, 5-(1,3-benzodioxol-5-ylmethylene)- chemical structure, C11H7NO4S, CAS 6318-41-8

2,4-Thiazolidinedione, 5-(1,3-benzodioxol-5-ylmethylene)-

CAS 6318-41-8C₁₁H₇NO₄S

(5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-1,3-thiazolidine-2,4-dione chemical structure, C11H7NO4S, CAS 1146702-72-8

(5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-1,3-thiazolidine-2,4-dione

CAS 1146702-72-8C₁₁H₇NO₄S

Methyl {(5E)-5-[(6-ethoxy-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C16H15NO7S, CAS 678147-31-4

Methyl {(5E)-5-[(6-ethoxy-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate

CAS 678147-31-4C₁₆H₁₅NO₇S

Methyl {(5E)-5-[(6-methoxy-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C15H13NO7S, CAS 676334-55-7

Methyl {(5E)-5-[(6-methoxy-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate

CAS 676334-55-7C₁₅H₁₃NO₇S

(5E)-5-[(6-Ethoxy-1,3-benzodioxol-5-yl)methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione chemical structure, C16H13NO5S, CAS 676470-95-4

(5E)-5-[(6-Ethoxy-1,3-benzodioxol-5-yl)methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione

CAS 676470-95-4C₁₆H₁₃NO₅S

(5Z)-5-[(6-Nitro-1,3-benzodioxol-5-yl)methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione chemical structure, C14H10N2O6S, CAS 675132-08-8

(5Z)-5-[(6-Nitro-1,3-benzodioxol-5-yl)methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione

CAS 675132-08-8C₁₄H₁₀N₂O₆S

(5E)-3-Ethyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione chemical structure, C14H13NO5S, CAS 677733-40-3

(5E)-3-Ethyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

CAS 677733-40-3C₁₄H₁₃NO₅S

N-(2-(5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2,4-dioxothiazolidin-3-yl)ethyl)-2-chloroacetamide chemical structure, C15H13ClN2O5S

N-(2-(5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2,4-dioxothiazolidin-3-yl)ethyl)-2-chloroacetamide

C₁₅H₁₃ClN₂O₅S

N-(2-{5-[(1,3-Dioxaindan-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}ethyl)-2-chloroacetamide chemical structure, C15H13ClN2O5S

N-(2-{5-[(1,3-Dioxaindan-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}ethyl)-2-chloroacetamide

C₁₅H₁₃ClN₂O₅S

N-[2-[5-(1,3-Benzodioxol-5-ylmethylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]-2-chloroacetamide chemical structure, C15H13ClN2O5S, CAS 554423-46-0

N-[2-[5-(1,3-Benzodioxol-5-ylmethylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]-2-chloroacetamide

CAS 554423-46-0C₁₅H₁₃ClN₂O₅S

AS 604850 chemical structure, C11H5F2NO4S, CAS 648449-76-7

CAS 648449-76-7C₁₁H₅F₂NO₄S

Ethyl {(5E)-5-[(6-chloro-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C15H12ClNO6S, CAS 432013-94-0

Ethyl {(5E)-5-[(6-chloro-1,3-benzodioxol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate

CAS 432013-94-0C₁₅H₁₂ClNO₆S

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione chemical structure, C11H5F2NO4S

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione

C₁₁H₅F₂NO₄S

5-[(Z)-1,3-Benzodioxol-5-ylmethylidene]-3-methyl-1,3-thiazolane-2,4-dione chemical structure, C12H9NO4S, CAS 366486-15-9

5-[(Z)-1,3-Benzodioxol-5-ylmethylidene]-3-methyl-1,3-thiazolane-2,4-dione

CAS 366486-15-9C₁₂H₉NO₄S

(5Z)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride chemical structure, C13H13ClN2O4S, CAS 1094609-08-1

(5Z)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride

CAS 1094609-08-1C₁₃H₁₃ClN₂O₄S

(5E)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride chemical structure, C13H13ClN2O4S

(5E)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride

C₁₃H₁₃ClN₂O₄S

5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione chemical structure, C11H5F2NO4S

5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione

C₁₁H₅F₂NO₄S

(5E)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride chemical structure, C13H13ClN2O4S

(5E)-3-(2-Aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-1,3-thiazolidine-2,4-dione hydrochloride

C₁₃H₁₃ClN₂O₄S

5-[(7-Methoxy-2H-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione chemical structure, C12H9NO5S, CAS 648449-74-5

5-[(7-Methoxy-2H-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

CAS 648449-74-5C₁₂H₉NO₅S