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Murcko scaffold

Ring system with 3 rings and 18 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(Nc1nncs1)c1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nncs1)c1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C15H13N3OS, CAS 361183-53-1
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 361183-53-1C15H13N3OS
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-3-methoxy-2-naphthamide chemical structure, C16H15N3O2S2, CAS 392239-70-2
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-3-methoxy-2-naphthamide
CAS 392239-70-2C16H15N3O2S2
N-(5-Methyl-1,3,4-thiadiazol-2-yl)naphthalene-2-carboxamide chemical structure, C14H11N3OS, CAS 391863-89-1
N-(5-Methyl-1,3,4-thiadiazol-2-yl)naphthalene-2-carboxamide
CAS 391863-89-1C14H11N3OS
N-(5-(Isopropylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C16H15N3OS2, CAS 391875-58-4
N-(5-(Isopropylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391875-58-4C16H15N3OS2
N-(5-(Propylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C16H15N3OS2, CAS 391875-21-1
N-(5-(Propylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391875-21-1C16H15N3OS2
Ethyl 2-[[5-(naphthalene-2-carbonylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoate chemical structure, C18H17N3O3S2, CAS 391874-93-4
Ethyl 2-[[5-(naphthalene-2-carbonylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoate
CAS 391874-93-4C18H17N3O3S2
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C15H13N3OS2, CAS 391864-02-1
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391864-02-1C15H13N3OS2
N-(5-(Butylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C17H17N3OS2, CAS 391875-89-1
N-(5-(Butylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391875-89-1C17H17N3OS2
Ethyl 2-{[5-(naphthalene-2-amido)-1,3,4-thiadiazol-2-yl]sulfanyl}acetate chemical structure, C17H15N3O3S2, CAS 391874-84-3
Ethyl 2-{[5-(naphthalene-2-amido)-1,3,4-thiadiazol-2-yl]sulfanyl}acetate
CAS 391874-84-3C17H15N3O3S2
N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C16H15N3OS, CAS 391864-23-6
N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391864-23-6C16H15N3OS
N-(5-(Methylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C14H11N3OS2, CAS 391875-74-4
N-(5-(Methylthio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 391875-74-4C14H11N3OS2
N-(5-((2-Amino-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-2-naphthamide chemical structure, C15H12N4O2S2, CAS 893154-08-0
N-(5-((2-Amino-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-2-naphthamide
CAS 893154-08-0C15H12N4O2S2