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Murcko scaffold

Ring system with 3 rings and 16 atoms

43 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
43
With full pages
19
Scaffold SMILES

O=C1Nc2cccnc2Nc2ncccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2cccnc2Nc2ncccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

N11-Ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H14N4O, CAS 132312-85-7
N11-Ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 132312-85-7C14H14N4O
N11-Ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C13H12N4O, CAS 133626-96-7
N11-Ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133626-96-7C13H12N4O
N5-Methyl-N11-propyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H16N4O, CAS 132312-81-3
N5-Methyl-N11-propyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 132312-81-3C15H16N4O
N11-Isopropyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H14N4O, CAS 133627-00-6
N11-Isopropyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-00-6C14H14N4O
N11-(t-Butyl)-N5-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one chemical structure, C16H18N4O, CAS 133627-01-7
N11-(t-Butyl)-N5-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS 133627-01-7C16H18N4O
N5-Methyl-N11-(2-propenyl)-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H14N4O, CAS 133627-03-9
N5-Methyl-N11-(2-propenyl)-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-03-9C15H14N4O
N5-Methyl-N11-(2-propynyl)-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H12N4O, CAS 133627-04-0
N5-Methyl-N11-(2-propynyl)-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-04-0C15H12N4O
N11-Butyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one chemical structure, C15H16N4O, CAS 133627-05-1
N11-Butyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS 133627-05-1C15H16N4O
N5-Acetyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H14N4O2, CAS 133648-15-4
N5-Acetyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133648-15-4C15H14N4O2
N11-Acetyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H12N4O2, CAS 133648-16-5
N11-Acetyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133648-16-5C14H12N4O2
N11-(2-Fluoroethyl)-N5-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one chemical structure, C14H13FN4O, CAS 133627-08-4
N11-(2-Fluoroethyl)-N5-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS 133627-08-4C14H13FN4O
N5-Methyl-N11-methylsulfonyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C13H12N4O3S, CAS 133627-09-5
N5-Methyl-N11-methylsulfonyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-09-5C13H12N4O3S
N5-Methyl-N11-(methylthio)methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H14N4OS, CAS 133627-10-8
N5-Methyl-N11-(methylthio)methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-10-8C14H14N4OS
2,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H16N4O, CAS 133627-11-9
2,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-11-9C15H16N4O
2-Chloro-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H13ClN4O, CAS 133627-12-0
2-Chloro-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-12-0C14H13ClN4O
3,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H16N4O, CAS 133627-13-1
3,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-13-1C15H16N4O
3-Chloro-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H13ClN4O, CAS 133627-14-2
3-Chloro-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-14-2C14H13ClN4O
N11-Ethyl-N5-methyl-3-nitro-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H13N5O3, CAS 133627-15-3
N11-Ethyl-N5-methyl-3-nitro-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-15-3C14H13N5O3
3-Amino-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H15N5O, CAS 133627-16-4
3-Amino-N11-ethyl-N5-methyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-16-4C14H15N5O
BIRH 414 chemical structure, C14H14N4O, CAS 133627-17-5
BIRH 414
CAS 133627-17-5C14H14N4O
4,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H16N4O, CAS 133627-18-6
4,N5-Dimethyl-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-18-6C15H16N4O
4-Chloro-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C13H11ClN4O, CAS 133627-20-0
4-Chloro-N11-ethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-20-0C13H11ClN4O
4,N11-Diethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C15H16N4O, CAS 133627-21-1
4,N11-Diethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-21-1C15H16N4O
N11-Ethyl-4-methoxy-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one chemical structure, C14H14N4O2, CAS 133627-22-2
N11-Ethyl-4-methoxy-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
CAS 133627-22-2C14H14N4O2