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Murcko scaffold

5-Methylene-10,11-dihydro-5H-dibenzo[a,d][7]annulene scaffold

78 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
78
With full pages
20
Scaffold SMILES

C=C1c2ccccc2CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Methylene-10,11-dihydro-5H-dibenzo[a,d][7]annulene page
Murcko scaffold C=C1c2ccccc2CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 78 chemicals

Amitriptyline chemical structure, C20H23N, CAS 50-48-6
Amitriptyline
CAS 50-48-6C20H23N
Nortriptyline chemical structure, C19H21N, CAS 72-69-5
Nortriptyline
CAS 72-69-5C19H21N
Amitriptyline hydrochloride chemical structure, C20H24ClN, CAS 549-18-8
Amitriptyline hydrochloride
CAS 549-18-8C20H24ClN
Amitriptylinoxide chemical structure, C20H23NO, CAS 4317-14-0
Amitriptylinoxide
CAS 4317-14-0C20H23NO
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-diethyl- chemical structure, C22H27N, CAS 4687-46-1
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-diethyl-
CAS 4687-46-1C22H27N
Nortriptyline ethyl carbamate chemical structure, C22H25NO2, CAS 16234-88-1
Nortriptyline ethyl carbamate
CAS 16234-88-1C22H25NO2
5H-Dibenzo(a,d)cycloheptene-4-methylamine 10,11-dihydro-N,N-dimethyl-5-methylene- chemical structure, C19H21N, CAS 33953-64-9
5H-Dibenzo(a,d)cycloheptene-4-methylamine 10,11-dihydro-N,N-dimethyl-5-methylene-
CAS 33953-64-9C19H21N
5H-Dibenzo(a,d)cycloheptene-4-ethylamine, 10,11-dihydro-N,N-dimethyl-5-methylene- chemical structure, C20H23N, CAS 36065-45-9
5H-Dibenzo(a,d)cycloheptene-4-ethylamine, 10,11-dihydro-N,N-dimethyl-5-methylene-
CAS 36065-45-9C20H23N
5H-Dibenzo(a,d)cycloheptene-4-propylamine, 10,11-dihydro-N,N-dimethyl-5-methylene- chemical structure, C21H25N, CAS 36065-46-0
5H-Dibenzo(a,d)cycloheptene-4-propylamine, 10,11-dihydro-N,N-dimethyl-5-methylene-
CAS 36065-46-0C21H25N
5H-Dibenzo(a,d)cycloheptene-4-methylamine, 10,11-dihydro-N-methyl-5-methylene- chemical structure, C18H19N, CAS 36065-47-1
5H-Dibenzo(a,d)cycloheptene-4-methylamine, 10,11-dihydro-N-methyl-5-methylene-
CAS 36065-47-1C18H19N
5H-Dibenzo(a,d)cycloheptene-4-ethylamine, 10,11-dihydro-5-methylene- chemical structure, C18H19N, CAS 36065-48-2
5H-Dibenzo(a,d)cycloheptene-4-ethylamine, 10,11-dihydro-5-methylene-
CAS 36065-48-2C18H19N
Dibenzo(a,d)cycloheptene-4-propylamine, 10,11-dihydro-N-methyl-5-methylene- chemical structure, C20H23N, CAS 36275-23-7
Dibenzo(a,d)cycloheptene-4-propylamine, 10,11-dihydro-N-methyl-5-methylene-
CAS 36275-23-7C20H23N
Ethylenediamine, N-(2-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylene)ethyl)-N',N'-dimethyl-, dihydrochloride chemical structure, C21H28Cl2N2, CAS 62469-24-3
Ethylenediamine, N-(2-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylene)ethyl)-N',N'-dimethyl-, dihydrochloride
CAS 62469-24-3C21H28Cl2N2
Ethylenediamine, N-(2-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylene)ethyl)-N',N'-diethyl-, dihydrochloride chemical structure, C23H32Cl2N2, CAS 62469-25-4
Ethylenediamine, N-(2-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylene)ethyl)-N',N'-diethyl-, dihydrochloride
CAS 62469-25-4C23H32Cl2N2
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N-methoxy-N-methyl- chemical structure, C20H23NO, CAS 67195-24-8
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N-methoxy-N-methyl-
CAS 67195-24-8C20H23NO
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-beta,beta,N,N-tetramethyl- chemical structure, C22H27N, CAS 67195-25-9
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-beta,beta,N,N-tetramethyl-
CAS 67195-25-9C22H27N
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-beta,N,N-trimethyl- chemical structure, C21H25N, CAS 67195-26-0
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-beta,N,N-trimethyl-
CAS 67195-26-0C21H25N
5H-Dibenzo(a,d)cycloheptene, 10,11-dihydro-5-(3-dimethylaminobutylidene)-, hydrochloride chemical structure, C21H26ClN, CAS 73927-66-9
5H-Dibenzo(a,d)cycloheptene, 10,11-dihydro-5-(3-dimethylaminobutylidene)-, hydrochloride
CAS 73927-66-9C21H26ClN
Cotriptyline chemical structure, C20H21NO, CAS 34662-67-4
Cotriptyline
CAS 34662-67-4C20H21NO
10-Hydroxynortriptyline chemical structure, C19H21NO, CAS 1156-99-6
10-Hydroxynortriptyline
CAS 1156-99-6C19H21NO
10-Hydroxyamitriptyline chemical structure, C20H23NO, CAS 1159-82-6
10-Hydroxyamitriptyline
CAS 1159-82-6C20H23NO
Desmethylnortriptyline chemical structure, C18H19N, CAS 4444-42-2
Desmethylnortriptyline
CAS 4444-42-2C18H19N
Dimethylprotriptyline chemical structure, C21H26N+, CAS 55032-41-2
Dimethylprotriptyline
CAS 55032-41-2C21H26N+
2-Propanone, 1-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-3-(dimethylamino)-, monohydrochloride chemical structure, C20H22ClNO, CAS 27448-03-9
2-Propanone, 1-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-3-(dimethylamino)-, monohydrochloride
CAS 27448-03-9C20H22ClNO