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Murcko scaffold

Ring system with 2 rings and 12 atoms

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
97
With full pages
12
Scaffold SMILES

c1ccc(CB2OCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CB2OCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

2-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C13H19BO2, CAS 87100-28-5
2-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 87100-28-5C13H19BO2
2-[(4-Ethenylphenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H21BO2, CAS 477841-91-1
2-[(4-Ethenylphenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 477841-91-1C15H21BO2
(R)-4,4,5,5-Tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane chemical structure, C14H21BO2, CAS 257298-92-3
(R)-4,4,5,5-Tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane
CAS 257298-92-3C14H21BO2
4-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzonitrile chemical structure, C14H18BNO2, CAS 475250-43-2
4-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzonitrile
CAS 475250-43-2C14H18BNO2
2-[(4-Fluorophenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C13H18BFO2, CAS 243145-83-7
2-[(4-Fluorophenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 243145-83-7C13H18BFO2
2-(4-Bromobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C13H18BBrO2, CAS 477841-90-0
2-(4-Bromobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 477841-90-0C13H18BBrO2
4-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-2-one chemical structure, C16H23BO3, CAS 199999-44-5
4-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-2-one
CAS 199999-44-5C16H23BO3
Methyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate chemical structure, C15H21BO4, CAS 517920-56-8
Methyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate
CAS 517920-56-8C15H21BO4
4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane chemical structure, C14H18BF3O2, CAS 475250-54-5
4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane
CAS 475250-54-5C14H18BF3O2
4,4,5,5-Tetramethyl-2-[(3-methylphenyl)methyl]-1,3,2-dioxaborolane chemical structure, C14H21BO2, CAS 365564-12-1
4,4,5,5-Tetramethyl-2-[(3-methylphenyl)methyl]-1,3,2-dioxaborolane
CAS 365564-12-1C14H21BO2
RefChem:336435 chemical structure, C14H20BClO2, CAS 257298-95-6
RefChem:336435
CAS 257298-95-6C14H20BClO2
4,4,5,5-Tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane chemical structure, C14H21BO2, CAS 174090-36-9
4,4,5,5-Tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane
CAS 174090-36-9C14H21BO2
2-[(3-Methoxyphenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C14H21BO3, CAS 797762-23-3
2-[(3-Methoxyphenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 797762-23-3C14H21BO3
2-(4-Isopropylbenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C16H25BO2, CAS 390381-03-0
2-(4-Isopropylbenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 390381-03-0C16H25BO2
1-(2-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)phenyl)ethanone chemical structure, C15H21BO3, CAS 149989-80-0
1-(2-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)phenyl)ethanone
CAS 149989-80-0C15H21BO3
2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C14H21BO3, CAS 475250-52-3
2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 475250-52-3C14H21BO3
Methyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate chemical structure, C15H21BO4, CAS 150033-80-0
Methyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate
CAS 150033-80-0C15H21BO4
3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanal chemical structure, C15H21BO3, CAS 264144-78-7
3-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanal
CAS 264144-78-7C15H21BO3
2-Methoxycarbonyl-1-phenylethylboronic acid pinacol ester chemical structure, C16H23BO4, CAS 364634-27-5
2-Methoxycarbonyl-1-phenylethylboronic acid pinacol ester
CAS 364634-27-5C16H23BO4
4,4,5,5-Tetramethyl-2-[1-(4-methylphenyl)ethyl]-1,3,2-dioxaborolane chemical structure, C15H23BO2, CAS 280559-36-6
4,4,5,5-Tetramethyl-2-[1-(4-methylphenyl)ethyl]-1,3,2-dioxaborolane
CAS 280559-36-6C15H23BO2
4,4,5,5-Tetramethyl-2-(4-(trifluoromethoxy)benzyl)-1,3,2-dioxaborolane chemical structure, C14H18BF3O3, CAS 872038-32-9
4,4,5,5-Tetramethyl-2-(4-(trifluoromethoxy)benzyl)-1,3,2-dioxaborolane
CAS 872038-32-9C14H18BF3O3
4,4,5,5-Tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane chemical structure, C14H21BO2, CAS 356570-52-0
4,4,5,5-Tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane
CAS 356570-52-0C14H21BO2
2-(1-(4-Fluorophenyl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C14H20BFO2, CAS 1138077-60-7
2-(1-(4-Fluorophenyl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1138077-60-7C14H20BFO2
4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane chemical structure, C14H18BF3O2, CAS 475250-46-5
4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane
CAS 475250-46-5C14H18BF3O2