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Murcko scaffold

Ring system with 4 rings and 27 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
12
With full pages
1
Scaffold SMILES

O=C(Oc1ccc2c(c1)C=CCN2C(=O)c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccc2c(c1)C=CCN2C(=O)c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1-(3-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 3-methoxybenzoate chemical structure, C28H27NO5, CAS 332019-40-6
1-(3-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 3-methoxybenzoate
CAS 332019-40-6C28H27NO5
Benzoic acid 1-benzoyl-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl ester chemical structure, C26H23NO3, CAS 332019-37-1
Benzoic acid 1-benzoyl-2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl ester
CAS 332019-37-1C26H23NO3
1-(4-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 4-methoxybenzoate chemical structure, C28H27NO5, CAS 330829-53-3
1-(4-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 4-methoxybenzoate
CAS 330829-53-3C28H27NO5
[1-(4-Fluorobenzoyl)-2,2,4-trimethylquinolin-6-yl] 4-nitrobenzoate chemical structure, C26H21FN2O5, CAS 355401-67-1
[1-(4-Fluorobenzoyl)-2,2,4-trimethylquinolin-6-yl] 4-nitrobenzoate
CAS 355401-67-1C26H21FN2O5
1-(4-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl benzoate chemical structure, C27H25NO4, CAS 356085-61-5
1-(4-Methoxybenzoyl)-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl benzoate
CAS 356085-61-5C27H25NO4
[2,2,4-Trimethyl-1-(3,4,5-trimethoxybenzoyl)quinolin-6-yl] 3,4,5-trimethoxybenzoate chemical structure, C32H35NO9, CAS 351468-20-7
[2,2,4-Trimethyl-1-(3,4,5-trimethoxybenzoyl)quinolin-6-yl] 3,4,5-trimethoxybenzoate
CAS 351468-20-7C32H35NO9
2,2,4-Trimethyl-1-[(4-methylphenyl)carbonyl]-1,2-dihydroquinolin-6-yl 4-methylbenzoate chemical structure, C28H27NO3, CAS 351192-29-5
2,2,4-Trimethyl-1-[(4-methylphenyl)carbonyl]-1,2-dihydroquinolin-6-yl 4-methylbenzoate
CAS 351192-29-5C28H27NO3
1-[(3,4-Dimethoxyphenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 3,4-dimethoxybenzoate chemical structure, C30H31NO7, CAS 669749-11-5
1-[(3,4-Dimethoxyphenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 3,4-dimethoxybenzoate
CAS 669749-11-5C30H31NO7
1-(4-Fluorobenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 4-fluorobenzoate chemical structure, C26H21F2NO3, CAS 332019-39-3
1-(4-Fluorobenzoyl)-2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 4-fluorobenzoate
CAS 332019-39-3C26H21F2NO3
1-[(2-Methoxyphenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 2-methoxybenzoate chemical structure, C28H27NO5, CAS 433952-69-3
1-[(2-Methoxyphenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 2-methoxybenzoate
CAS 433952-69-3C28H27NO5
1-[(2-Fluorophenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 2-fluorobenzoate chemical structure, C26H21F2NO3, CAS 674361-31-0
1-[(2-Fluorophenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 2-fluorobenzoate
CAS 674361-31-0C26H21F2NO3
1-[(3-Fluorophenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 3-fluorobenzoate chemical structure, C26H21F2NO3, CAS 351192-27-3
1-[(3-Fluorophenyl)carbonyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl 3-fluorobenzoate
CAS 351192-27-3C26H21F2NO3