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Murcko scaffold

Ring system with 2 rings and 17 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(CCSc1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCSc1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-[5-(Methoxymethyl)-1,3,4-thiadiazol-2-yl]-3-phenylsulfanylpropanamide chemical structure, C13H15N3O2S2, CAS 827619-48-7
N-[5-(Methoxymethyl)-1,3,4-thiadiazol-2-yl]-3-phenylsulfanylpropanamide
CAS 827619-48-7C13H15N3O2S2
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]-3-phenylsulfanylpropanamide chemical structure, C15H19N3O2S2, CAS 827618-82-6
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]-3-phenylsulfanylpropanamide
CAS 827618-82-6C15H19N3O2S2
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-3-phenylsulfanylpropanamide chemical structure, C12H13N3OS2, CAS 774548-81-1
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-3-phenylsulfanylpropanamide
CAS 774548-81-1C12H13N3OS2
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-phenylsulfanylpropanamide chemical structure, C15H19N3OS2, CAS 827618-81-5
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-phenylsulfanylpropanamide
CAS 827618-81-5C15H19N3OS2
3-(4-Chlorophenyl)sulfanyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)propanamide chemical structure, C14H16ClN3OS2, CAS 879080-07-6
3-(4-Chlorophenyl)sulfanyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)propanamide
CAS 879080-07-6C14H16ClN3OS2
3-(4-Chlorophenyl)sulfanyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C12H9ClF3N3OS2, CAS 881944-56-5
3-(4-Chlorophenyl)sulfanyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 881944-56-5C12H9ClF3N3OS2
3-(4-Chlorophenyl)sulfanyl-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C13H14ClN3O2S2, CAS 878977-26-5
3-(4-Chlorophenyl)sulfanyl-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 878977-26-5C13H14ClN3O2S2
3-(4-Chlorophenyl)sulfanyl-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C15H18ClN3O2S2, CAS 879080-08-7
3-(4-Chlorophenyl)sulfanyl-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 879080-08-7C15H18ClN3O2S2
3-(4-Chlorophenyl)sulfanyl-N-(1,3,4-thiadiazol-2-yl)propanamide chemical structure, C11H10ClN3OS2, CAS 879080-05-4
3-(4-Chlorophenyl)sulfanyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CAS 879080-05-4C11H10ClN3OS2
N-[5-(Ethoxymethyl)-1,3,4-thiadiazol-2-yl]-3-[(4-methylphenyl)sulfanyl]propanamide chemical structure, C15H19N3O2S2, CAS 905810-46-0
N-[5-(Ethoxymethyl)-1,3,4-thiadiazol-2-yl]-3-[(4-methylphenyl)sulfanyl]propanamide
CAS 905810-46-0C15H19N3O2S2
3-[(4-Aminophenyl)thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)propanamide chemical structure, C12H14N4OS2, CAS 931292-80-7
3-[(4-Aminophenyl)thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)propanamide
CAS 931292-80-7C12H14N4OS2