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Murcko scaffold

2-(Piperidin-4-yl)pyrimidine scaffold

133 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
133
With full pages
6
Scaffold SMILES

c1cnc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyrimidine page
Murcko scaffold c1cnc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 133 chemicals

4,6-Dimethoxy-2-piperidin-4-ylpyrimidine chemical structure, C11H17N3O2, CAS 849924-99-8
4,6-Dimethoxy-2-piperidin-4-ylpyrimidine
CAS 849924-99-8C11H17N3O2
2-(Piperidin-4-yl)pyrimidine chemical structure, C9H13N3, CAS 151389-25-2
2-(Piperidin-4-yl)pyrimidine
CAS 151389-25-2C9H13N3
tert-Butyl 4-(pyrimidin-2-yl)piperidine-1-carboxylate chemical structure, C14H21N3O2, CAS 182416-05-3
tert-Butyl 4-(pyrimidin-2-yl)piperidine-1-carboxylate
CAS 182416-05-3C14H21N3O2
2-(1-Methylpiperidin-4-yl)pyrimidine chemical structure, C10H15N3, CAS 1630799-55-1
2-(1-Methylpiperidin-4-yl)pyrimidine
CAS 1630799-55-1C10H15N3
tert-Butyl 4-hydroxy-4-(pyrimidin-2-yl)piperidine-1-carboxylate chemical structure, C14H21N3O3, CAS 182416-02-0
tert-Butyl 4-hydroxy-4-(pyrimidin-2-yl)piperidine-1-carboxylate
CAS 182416-02-0C14H21N3O3
4-Chloro-2-(4-piperidin-4-yl)pyrimidine chemical structure, C9H12ClN3, CAS 1159822-16-8
4-Chloro-2-(4-piperidin-4-yl)pyrimidine
CAS 1159822-16-8C9H12ClN3
2-(Piperidin-4-yl)pyrimidin-4-amine chemical structure, C9H14N4, CAS 1159814-28-4
2-(Piperidin-4-yl)pyrimidin-4-amine
CAS 1159814-28-4C9H14N4
4-(Pyrimidin-2-yl)piperidin-4-ol chemical structure, C9H13N3O, CAS 861217-38-1
4-(Pyrimidin-2-yl)piperidin-4-ol
CAS 861217-38-1C9H13N3O
4-Methyl-2-(piperidin-4-yl)pyrimidine chemical structure, C10H15N3, CAS 1316218-93-5
4-Methyl-2-(piperidin-4-yl)pyrimidine
CAS 1316218-93-5C10H15N3
5-Chloro-2-(piperidin-4-yl)pyrimidine chemical structure, C9H12ClN3, CAS 944903-10-0
5-Chloro-2-(piperidin-4-yl)pyrimidine
CAS 944903-10-0C9H12ClN3
2-(Piperidin-4-yl)pyrimidine hydrochloride chemical structure, C9H14ClN3, CAS 690261-64-4
2-(Piperidin-4-yl)pyrimidine hydrochloride
CAS 690261-64-4C9H14ClN3
tert-Butyl 4-(5-hydroxypyrimidin-2-yl)piperidine-1-carboxylate chemical structure, C14H21N3O3, CAS 1379522-56-1
tert-Butyl 4-(5-hydroxypyrimidin-2-yl)piperidine-1-carboxylate
CAS 1379522-56-1C14H21N3O3
Methyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)pyrimidine-4-carboxylate chemical structure, C16H23N3O4, CAS 1205678-34-7
Methyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)pyrimidine-4-carboxylate
CAS 1205678-34-7C16H23N3O4
4,5,6-Trimethyl-2-(piperidin-4-yl)pyrimidine chemical structure, C12H19N3, CAS 1344248-43-6
4,5,6-Trimethyl-2-(piperidin-4-yl)pyrimidine
CAS 1344248-43-6C12H19N3
2-(Piperidin-4-yl)-4-(trifluoromethyl)pyrimidine chemical structure, C10H12F3N3, CAS 1221278-89-2
2-(Piperidin-4-yl)-4-(trifluoromethyl)pyrimidine
CAS 1221278-89-2C10H12F3N3
4,6-Dimethyl-2-(piperidin-4-yl)pyrimidine chemical structure, C11H17N3, CAS 1342653-54-6
4,6-Dimethyl-2-(piperidin-4-yl)pyrimidine
CAS 1342653-54-6C11H17N3
5-Bromo-2-(piperidin-4-yl)pyrimidine chemical structure, C9H12BrN3, CAS 1256818-45-7
5-Bromo-2-(piperidin-4-yl)pyrimidine
CAS 1256818-45-7C9H12BrN3
5-Methyl-2-(piperidin-4-yl)pyrimidine chemical structure, C10H15N3, CAS 1256825-35-0
5-Methyl-2-(piperidin-4-yl)pyrimidine
CAS 1256825-35-0C10H15N3
5-Ethyl-4,6-dimethyl-2-(piperidin-4-yl)pyrimidine chemical structure, C13H21N3, CAS 1341685-75-3
5-Ethyl-4,6-dimethyl-2-(piperidin-4-yl)pyrimidine
CAS 1341685-75-3C13H21N3
4-Ethyl-6-methyl-2-(piperidin-4-yl)pyrimidine chemical structure, C12H19N3, CAS 1341076-29-6
4-Ethyl-6-methyl-2-(piperidin-4-yl)pyrimidine
CAS 1341076-29-6C12H19N3
4-Methyl-2-(piperidin-4-yl)-6-(propan-2-yl)pyrimidine chemical structure, C13H21N3, CAS 1341695-07-5
4-Methyl-2-(piperidin-4-yl)-6-(propan-2-yl)pyrimidine
CAS 1341695-07-5C13H21N3
1-(4-(4-Chloro-6-methylpyrimidin-2-yl)piperidin-1-yl)ethanone chemical structure, C12H16ClN3O, CAS 1316223-78-5
1-(4-(4-Chloro-6-methylpyrimidin-2-yl)piperidin-1-yl)ethanone
CAS 1316223-78-5C12H16ClN3O
1-(4-(4-Chloro-6-methylpyrimidin-2-yl)piperidin-1-yl)-2-methoxyethanone chemical structure, C13H18ClN3O2, CAS 1316220-59-3
1-(4-(4-Chloro-6-methylpyrimidin-2-yl)piperidin-1-yl)-2-methoxyethanone
CAS 1316220-59-3C13H18ClN3O2
4-(4-Chloro-6-methylpyrimidin-2-yl)-N,N-dimethylpiperidine-1-sulfonamide chemical structure, C12H19ClN4O2S, CAS 1316222-50-0
4-(4-Chloro-6-methylpyrimidin-2-yl)-N,N-dimethylpiperidine-1-sulfonamide
CAS 1316222-50-0C12H19ClN4O2S