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Murcko scaffold

Ring system with 2 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(C=Cc1ccccc1)NC(=S)Nc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NC(=S)Nc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

(E)-N-[(4-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide chemical structure, C16H15N3OS, CAS 1164502-56-0
(E)-N-[(4-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide
CAS 1164502-56-0C16H15N3OS
(E)-N-[(3-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide chemical structure, C16H15N3OS, CAS 364620-48-4
(E)-N-[(3-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide
CAS 364620-48-4C16H15N3OS
(E)-N-[(6-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide chemical structure, C16H15N3OS, CAS 364597-72-8
(E)-N-[(6-Methylpyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide
CAS 364597-72-8C16H15N3OS
(E)-N-[(5-Chloropyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide chemical structure, C15H12ClN3OS, CAS 78852-14-9
(E)-N-[(5-Chloropyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide
CAS 78852-14-9C15H12ClN3OS
(E)-3-(3-Nitrophenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide chemical structure, C15H12N4O3S, CAS 430446-06-3
(E)-3-(3-Nitrophenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide
CAS 430446-06-3C15H12N4O3S
(E)-3-(4-Chlorophenyl)-N-[(4-methylpyridin-2-yl)carbamothioyl]prop-2-enamide chemical structure, C16H14ClN3OS, CAS 1164484-39-2
(E)-3-(4-Chlorophenyl)-N-[(4-methylpyridin-2-yl)carbamothioyl]prop-2-enamide
CAS 1164484-39-2C16H14ClN3OS
(E)-3-(4-Methoxyphenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide chemical structure, C16H15N3O2S, CAS 642989-84-2
(E)-3-(4-Methoxyphenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide
CAS 642989-84-2C16H15N3O2S
(E)-N-[(5-Iodopyridin-2-yl)carbamothioyl]-3-(3-nitrophenyl)prop-2-enamide chemical structure, C15H11IN4O3S, CAS 535976-46-6
(E)-N-[(5-Iodopyridin-2-yl)carbamothioyl]-3-(3-nitrophenyl)prop-2-enamide
CAS 535976-46-6C15H11IN4O3S
(E)-N-[(5-Iodopyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide chemical structure, C15H12IN3OS, CAS 535966-44-0
(E)-N-[(5-Iodopyridin-2-yl)carbamothioyl]-3-phenylprop-2-enamide
CAS 535966-44-0C15H12IN3OS
(E)-N-[(5-Bromopyridin-2-yl)carbamothioyl]-3-(4-chlorophenyl)prop-2-enamide chemical structure, C15H11BrClN3OS, CAS 429649-95-6
(E)-N-[(5-Bromopyridin-2-yl)carbamothioyl]-3-(4-chlorophenyl)prop-2-enamide
CAS 429649-95-6C15H11BrClN3OS
(E)-3-(2,4-Dichlorophenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide chemical structure, C15H11Cl2N3OS, CAS 1164532-81-3
(E)-3-(2,4-Dichlorophenyl)-N-(pyridin-2-ylcarbamothioyl)prop-2-enamide
CAS 1164532-81-3C15H11Cl2N3OS
(E)-N-[(5-Chloropyridin-2-yl)carbamothioyl]-3-(3-nitrophenyl)prop-2-enamide chemical structure, C15H11ClN4O3S, CAS 430446-58-5
(E)-N-[(5-Chloropyridin-2-yl)carbamothioyl]-3-(3-nitrophenyl)prop-2-enamide
CAS 430446-58-5C15H11ClN4O3S
N-{[(5-Bromo-2-pyridinyl)amino]carbonothioyl}-3-phenylacrylamide chemical structure, C15H12BrN3OS, CAS 6162-40-9
N-{[(5-Bromo-2-pyridinyl)amino]carbonothioyl}-3-phenylacrylamide
CAS 6162-40-9C15H12BrN3OS