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Murcko scaffold

Ring system with 2 rings and 19 atoms

5 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
5
With full pages
5
Scaffold SMILES

O=C(COC(=O)c1ccc(=O)oc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1ccc(=O)oc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Phenacyl 2,4-dimethyl-6-oxopyran-3-carboxylate chemical structure, C16H14O5, CAS 109600-69-3
Phenacyl 2,4-dimethyl-6-oxopyran-3-carboxylate
CAS 109600-69-3C16H14O5
2-(4-Methyl-3-nitrophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate chemical structure, C17H15NO7, CAS 356079-52-2
2-(4-Methyl-3-nitrophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate
CAS 356079-52-2C17H15NO7
2-(4-Chlorophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate chemical structure, C16H13ClO5, CAS 318513-00-7
2-(4-Chlorophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate
CAS 318513-00-7C16H13ClO5
2-(3,4-Dichlorophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate chemical structure, C16H12Cl2O5, CAS 297743-20-5
2-(3,4-Dichlorophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate
CAS 297743-20-5C16H12Cl2O5
2-(4-Bromophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate chemical structure, C16H13BrO5, CAS 305858-25-7
2-(4-Bromophenyl)-2-oxoethyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate
CAS 305858-25-7C16H13BrO5