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Murcko scaffold

Cyclo(glycylprolyl) scaffold

87 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
87
With full pages
24
Scaffold SMILES

O=C1NCC(=O)N2CCCC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Cyclo(glycylprolyl) page
Murcko scaffold O=C1NCC(=O)N2CCCC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 87 chemicals

Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)- chemical structure, C10H16N2O2, CAS 5654-87-5
Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-
CAS 5654-87-5C10H16N2O2
3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione chemical structure, C11H18N2O2, CAS 5654-86-4
3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS 5654-86-4C11H18N2O2
Cyclo(prolylglycyl) chemical structure, C7H10N2O2, CAS 97011-16-0
Cyclo(prolylglycyl)
CAS 97011-16-0C7H10N2O2
Cyclo(glycylprolyl) chemical structure, C7H10N2O2, CAS 19179-12-5
Cyclo(glycylprolyl)
CAS 19179-12-5C7H10N2O2
Cyclo(lysyl-prolyl) chemical structure, C11H19N3O2, CAS 111688-85-8
Cyclo(lysyl-prolyl)
CAS 111688-85-8C11H19N3O2
3-Hydroxy-2,3-dimethyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4-dione chemical structure, C9H14N2O3, CAS 57101-29-8
3-Hydroxy-2,3-dimethyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS 57101-29-8C9H14N2O3
3-(Hydroxymethyl)hexahydropyrrolo[1,2-A]pyrazine-1,4-dione chemical structure, C8H12N2O3, CAS 308355-85-3
3-(Hydroxymethyl)hexahydropyrrolo[1,2-A]pyrazine-1,4-dione
CAS 308355-85-3C8H12N2O3
Verpacamide A chemical structure, C11H19N5O2, CAS 74838-83-8
Verpacamide A
CAS 74838-83-8C11H19N5O2
(R)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione chemical structure, C7H10N2O2, CAS 96193-26-9
(R)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS 96193-26-9C7H10N2O2
(3R,8aS)-Hexahydro-3-(1-methylethyl)pyrrolo(1,2-a)pyrazine-1,4-dione chemical structure, C10H16N2O2, CAS 27483-18-7
(3R,8aS)-Hexahydro-3-(1-methylethyl)pyrrolo(1,2-a)pyrazine-1,4-dione
CAS 27483-18-7C10H16N2O2
(3R,8aS)-Hexahydro-3-(2-methylpropyl)pyrrolo(1,2-a)pyrazine-1,4-dione chemical structure, C11H18N2O2, CAS 36238-67-2
(3R,8aS)-Hexahydro-3-(2-methylpropyl)pyrrolo(1,2-a)pyrazine-1,4-dione
CAS 36238-67-2C11H18N2O2
Cyclo(D)-Pro-(D)-Leu chemical structure, C11H18N2O2, CAS 274680-11-4
Cyclo(D)-Pro-(D)-Leu
CAS 274680-11-4C11H18N2O2
Amino({3-[(3S,8aS)-1,4-Dioxooctahydropyrrolo[1,2-A]pyrazin-3-Yl]propyl}amino)methaniminium chemical structure, C11H19N5O2, CAS 173524-51-1
Amino({3-[(3S,8aS)-1,4-Dioxooctahydropyrrolo[1,2-A]pyrazin-3-Yl]propyl}amino)methaniminium
CAS 173524-51-1C11H19N5O2
(3S,8aR)-3-Methyl-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione chemical structure, C8H12N2O2, CAS 19943-29-4
(3S,8aR)-3-Methyl-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione
CAS 19943-29-4C8H12N2O2
3-Methyl-octahydropyrrolo(1,2-a)piperazine-1,4-dione chemical structure, C8H12N2O2, CAS 65556-33-4
3-Methyl-octahydropyrrolo(1,2-a)piperazine-1,4-dione
CAS 65556-33-4C8H12N2O2
3-sec-Butyl-pyrrolopiperazine-1,4-dione chemical structure, C11H18N2O2, CAS 58917-56-9
3-sec-Butyl-pyrrolopiperazine-1,4-dione
CAS 58917-56-9C11H18N2O2
Cyclo(-Met-Pro) chemical structure, C10H16N2O2S, CAS 53049-06-2
Cyclo(-Met-Pro)
CAS 53049-06-2C10H16N2O2S
Cyclo(D)-Pro-(D)-Val chemical structure, C10H16N2O2, CAS 22155-59-5
Cyclo(D)-Pro-(D)-Val
CAS 22155-59-5C10H16N2O2
Cyclo(D-Pro-L-Val) chemical structure, C10H16N2O2, CAS 22155-58-4
Cyclo(D-Pro-L-Val)
CAS 22155-58-4C10H16N2O2
cyclo(L-Pro-L-Val) chemical structure, C10H16N2O2, CAS 2854-40-2
cyclo(L-Pro-L-Val)
CAS 2854-40-2C10H16N2O2
Gancidin W chemical structure, C11H18N2O2, CAS 2873-36-1
Gancidin W
CAS 2873-36-1C11H18N2O2
(3S,8AR)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione chemical structure, C11H18N2O2, CAS 32510-93-3
(3S,8AR)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS 32510-93-3C11H18N2O2
(3R,8aR)-3-Methyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione chemical structure, C8H12N2O2, CAS 19943-28-3
(3R,8aR)-3-Methyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS 19943-28-3C8H12N2O2
Cyclo-trans-4-L-Hydroxyprolyl-L-serine chemical structure, C8H12N2O4, CAS 211868-63-2
Cyclo-trans-4-L-Hydroxyprolyl-L-serine
CAS 211868-63-2C8H12N2O4