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Murcko scaffold

Ring system with 3 rings and 18 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
9
With full pages
6
Scaffold SMILES

O=S(=O)(c1ccccc1)c1cnn2cccnc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1cnn2cccnc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H13N3O2S, CAS 861209-12-3
5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine
CAS 861209-12-3C14H13N3O2S
3-(Phenylsulfonyl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H7F6N3O2S, CAS 865658-00-0
3-(Phenylsulfonyl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 865658-00-0C14H7F6N3O2S
6-(Methylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H12N4O4S2, CAS 685107-43-1
6-(Methylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 685107-43-1C13H12N4O4S2
6-(tert-Butylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-ylamine chemical structure, C16H18N4O4S2, CAS 439110-87-9
6-(tert-Butylsulfonyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-ylamine
CAS 439110-87-9C16H18N4O4S2
5-Methyl-3-(phenylsulfonyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H10F3N3O2S, CAS 685107-44-2
5-Methyl-3-(phenylsulfonyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 685107-44-2C14H10F3N3O2S
3-(Benzenesulfonyl)-5,6,7-trimethylpyrazolo[1,5-a]pyrimidine chemical structure, C15H15N3O2S, CAS 685108-12-7
3-(Benzenesulfonyl)-5,6,7-trimethylpyrazolo[1,5-a]pyrimidine
CAS 685108-12-7C15H15N3O2S
7-[Chloro(difluoro)methyl]-5-methyl-3-(phenylsulfonyl)pyrazolo[1,5-A]pyrimidine chemical structure, C14H10ClF2N3O2S, CAS 866049-88-9
7-[Chloro(difluoro)methyl]-5-methyl-3-(phenylsulfonyl)pyrazolo[1,5-A]pyrimidine
CAS 866049-88-9C14H10ClF2N3O2S
5,7-Dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo(1,5-a)pyrimidine chemical structure, C15H15N3O2S2, CAS 1173103-84-8
5,7-Dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo(1,5-a)pyrimidine
CAS 1173103-84-8C15H15N3O2S2
Avn-492 chemical structure, C17H21N5O2S, CAS 1220646-23-0
Avn-492
CAS 1220646-23-0C17H21N5O2S