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Murcko scaffold

3-Phenyl-5-pyrazolone scaffold

50 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
50
With full pages
13
Scaffold SMILES

O=C1CC(c2ccccc2)=NN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-5-pyrazolone page
Murcko scaffold O=C1CC(c2ccccc2)=NN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

3-Phenyl-5-pyrazolone chemical structure, C9H8N2O, CAS 4860-93-9
3-Phenyl-5-pyrazolone
CAS 4860-93-9C9H8N2O
3H-Pyrazol-3-one, 2,4-dihydro-2-methyl-5-phenyl- chemical structure, C10H10N2O, CAS 41927-50-8
3H-Pyrazol-3-one, 2,4-dihydro-2-methyl-5-phenyl-
CAS 41927-50-8C10H10N2O
4-Chloro-4-methyl-3-(4-nitrophenyl)-1H-pyrazol-5-one chemical structure, C10H8ClN3O3, CAS 13051-12-2
4-Chloro-4-methyl-3-(4-nitrophenyl)-1H-pyrazol-5-one
CAS 13051-12-2C10H8ClN3O3
4-Methyl-3-(4-nitrophenyl)-1,4-dihydropyrazol-5-one chemical structure, C10H9N3O3, CAS 13051-11-1
4-Methyl-3-(4-nitrophenyl)-1,4-dihydropyrazol-5-one
CAS 13051-11-1C10H9N3O3
4-Bromo-5-(4-methoxyphenyl)-4-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H11BrN2O2, CAS 13051-10-0
4-Bromo-5-(4-methoxyphenyl)-4-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 13051-10-0C11H11BrN2O2
4-(2-Hydroxyethyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H12N2O2, CAS 10244-77-6
4-(2-Hydroxyethyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 10244-77-6C11H12N2O2
5-Phenyl-4-(3-sulfanylpropyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C12H14N2OS, CAS 7767-85-3
5-Phenyl-4-(3-sulfanylpropyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 7767-85-3C12H14N2OS
5-(4-Methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C10H10N2O2, CAS 1578-89-8
5-(4-Methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 1578-89-8C10H10N2O2
3H-Pyrazol-3-one, 2,4-dihydro-5-(4-nitrophenyl)- chemical structure, C9H7N3O3, CAS 54945-13-0
3H-Pyrazol-3-one, 2,4-dihydro-5-(4-nitrophenyl)-
CAS 54945-13-0C9H7N3O3
3-(4-Bromophenyl)-1,4-dihydropyrazol-5-one chemical structure, C9H7BrN2O, CAS 103095-74-5
3-(4-Bromophenyl)-1,4-dihydropyrazol-5-one
CAS 103095-74-5C9H7BrN2O
2,4-Dihydro-5-[4-(1-methylethoxy)phenyl]-3H-pyrazol-3-one chemical structure, C12H14N2O2, CAS 442872-58-4
2,4-Dihydro-5-[4-(1-methylethoxy)phenyl]-3H-pyrazol-3-one
CAS 442872-58-4C12H14N2O2
4,5-Dihydro-5-oxo-3-phenyl-1H-pyrazole-1-carbothioamide chemical structure, C10H9N3OS, CAS 58197-04-9
4,5-Dihydro-5-oxo-3-phenyl-1H-pyrazole-1-carbothioamide
CAS 58197-04-9C10H9N3OS
3-(2-Hydroxyphenyl)-1H-pyrazol-5(4H)-one chemical structure, C9H8N2O2, CAS 5186-66-3
3-(2-Hydroxyphenyl)-1H-pyrazol-5(4H)-one
CAS 5186-66-3C9H8N2O2
3-(4-Fluorophenyl)-1H-pyrazol-5(4H)-one chemical structure, C9H7FN2O, CAS 264208-45-9
3-(4-Fluorophenyl)-1H-pyrazol-5(4H)-one
CAS 264208-45-9C9H7FN2O
5-(4-Chloro-phenyl)-2,4-dihydro-pyrazol-3-one chemical structure, C9H7ClN2O, CAS 59719-19-6
5-(4-Chloro-phenyl)-2,4-dihydro-pyrazol-3-one
CAS 59719-19-6C9H7ClN2O
5-(3-Methoxy-phenyl)-2,4-dihydro-pyrazol-3-one chemical structure, C10H10N2O2, CAS 886494-11-7
5-(3-Methoxy-phenyl)-2,4-dihydro-pyrazol-3-one
CAS 886494-11-7C10H10N2O2
2-Butyl-5-phenyl-2,4-dihydro-pyrazol-3-one chemical structure, C13H16N2O, CAS 901273-45-8
2-Butyl-5-phenyl-2,4-dihydro-pyrazol-3-one
CAS 901273-45-8C13H16N2O
5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde oxime chemical structure, C10H9N3O2, CAS 338975-53-4
5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde oxime
CAS 338975-53-4C10H9N3O2
5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde O-methyloxime chemical structure, C11H11N3O2, CAS 338975-49-8
5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde O-methyloxime
CAS 338975-49-8C11H11N3O2
2-(2-Hydroxyethyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H12N2O2, CAS 67056-21-7
2-(2-Hydroxyethyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 67056-21-7C11H12N2O2
5-(4-Methylphenyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C10H10N2O, CAS 66076-78-6
5-(4-Methylphenyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 66076-78-6C10H10N2O
3-(3,4-Dimethoxyphenyl)-4,4-dimethyl-1H-pyrazol-5(4H)-one chemical structure, C13H16N2O3, CAS 95644-24-9
3-(3,4-Dimethoxyphenyl)-4,4-dimethyl-1H-pyrazol-5(4H)-one
CAS 95644-24-9C13H16N2O3
3-(4-Chlorophenyl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C10H9ClN2O, CAS 173409-31-9
3-(4-Chlorophenyl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one
CAS 173409-31-9C10H9ClN2O
3-(3,4-Dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-5-one chemical structure, C11H12N2O3, CAS 264208-47-1
3-(3,4-Dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-5-one
CAS 264208-47-1C11H12N2O3