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Murcko scaffold

Ring system with 3 rings and 16 atoms

90 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
90
With full pages
3
Scaffold SMILES

O=c1ccn(C2OCC3OCOC32)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2OCC3OCOC32)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

2',3'-O-Isopropylideneuridine chemical structure, C12H16N2O6, CAS 362-43-6
2',3'-O-Isopropylideneuridine
CAS 362-43-6C12H16N2O6
2',3'-O-(Isopropylidene)uridine 5'-acetate chemical structure, C14H18N2O7, CAS 15922-23-3
2',3'-O-(Isopropylidene)uridine 5'-acetate
CAS 15922-23-3C14H18N2O7
5-Fluoro-1-[(4R,6R)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione chemical structure, C12H15FN2O6, CAS 2797-17-3
5-Fluoro-1-[(4R,6R)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione
CAS 2797-17-3C12H15FN2O6
1-[5-o-Carbamoyl-2,3-o-(1-methylethylidene)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione chemical structure, C13H17N3O7, CAS 41509-93-7
1-[5-o-Carbamoyl-2,3-o-(1-methylethylidene)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
CAS 41509-93-7C13H17N3O7
Antineoplastic-319728 chemical structure, C14H21AsN2O5S, CAS 84365-01-5
Antineoplastic-319728
CAS 84365-01-5C14H21AsN2O5S
[(3aR,4R,6R,6aR)-4-(2,4-Dioxopyrimidin-1-yl)-6-(hydroxymethyl)-2-methyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl]phosphonic acid chemical structure, C11H15N2O9P, CAS 656233-30-6
[(3aR,4R,6R,6aR)-4-(2,4-Dioxopyrimidin-1-yl)-6-(hydroxymethyl)-2-methyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl]phosphonic acid
CAS 656233-30-6C11H15N2O9P
[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2-methyl-4-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl]phosphonic acid chemical structure, C12H17N2O9P, CAS 656233-29-3
[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2-methyl-4-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl]phosphonic acid
CAS 656233-29-3C12H17N2O9P
5-Bromo-1-[(4R,6S)-6-(fluoromethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione chemical structure, C12H14BrFN2O5, CAS 73149-18-5
5-Bromo-1-[(4R,6S)-6-(fluoromethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione
CAS 73149-18-5C12H14BrFN2O5
5-Bromo-2',3'-O-isopropylideneuridine chemical structure, C12H15BrN2O6, CAS 54503-61-6
5-Bromo-2',3'-O-isopropylideneuridine
CAS 54503-61-6C12H15BrN2O6
Uridine, 3-methyl-2',3'-O-(1-methylethylidene)- chemical structure, C13H18N2O6, CAS 32471-59-3
Uridine, 3-methyl-2',3'-O-(1-methylethylidene)-
CAS 32471-59-3C13H18N2O6
Uridine, 5'-O-methyl-2',3'-O-(1-methylethylidene)- chemical structure, C13H18N2O6, CAS 67443-68-9
Uridine, 5'-O-methyl-2',3'-O-(1-methylethylidene)-
CAS 67443-68-9C13H18N2O6
5'-Deoxy-2',3'-O-(1-methylethylidene)-5'-oxouridine chemical structure, C12H14N2O6, CAS 27999-65-1
5'-Deoxy-2',3'-O-(1-methylethylidene)-5'-oxouridine
CAS 27999-65-1C12H14N2O6
2',3'-O-(1-Methoxyethylidene)uridine chemical structure, C12H16N2O7, CAS 16667-57-5
2',3'-O-(1-Methoxyethylidene)uridine
CAS 16667-57-5C12H16N2O7
5-Fluoro-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H15FN2O6
5-Fluoro-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
C12H15FN2O6
1-[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-5-iodopyrimidine-2,4-dione chemical structure, C12H15IN2O6, CAS 19556-58-2
1-[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-5-iodopyrimidine-2,4-dione
CAS 19556-58-2C12H15IN2O6
5-(2-Ethoxy-1-oxo-2-propenyl)-2',3'-O-(1-methylethylidene)uridine chemical structure, C17H22N2O8, CAS 165746-54-3
5-(2-Ethoxy-1-oxo-2-propenyl)-2',3'-O-(1-methylethylidene)uridine
CAS 165746-54-3C17H22N2O8
5'-O-(t-Butyldimethylsilyl)-2',3'-O-isopropylideneuridine chemical structure, C18H30N2O6Si, CAS 102147-76-2
5'-O-(t-Butyldimethylsilyl)-2',3'-O-isopropylideneuridine
CAS 102147-76-2C18H30N2O6Si
1-[(3aR,4R,6R,6aR)-6-(Azidomethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C12H15N5O5, CAS 15083-05-3
1-[(3aR,4R,6R,6aR)-6-(Azidomethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 15083-05-3C12H15N5O5
5-(Hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C13H18N2O7, CAS 3816-77-1
5-(Hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
CAS 3816-77-1C13H18N2O7
2',3'-O-Isopropylidene-5-fluorouridine chemical structure, C12H15FN2O6
2',3'-O-Isopropylidene-5-fluorouridine
C12H15FN2O6
5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-fluorouridine chemical structure, C12H14FIN2O5, CAS 61787-10-8
5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-fluorouridine
CAS 61787-10-8C12H14FIN2O5
5'-Deoxy-2',3'-O-isopropylidene-5-fluorouridine chemical structure, C12H15FN2O5
5'-Deoxy-2',3'-O-isopropylidene-5-fluorouridine
C12H15FN2O5
5-Fluoro-1-((3aR,4R,6R,6aR)-2,2,6-trimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H15FN2O5, CAS 66335-39-5
5-Fluoro-1-((3aR,4R,6R,6aR)-2,2,6-trimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
CAS 66335-39-5C12H15FN2O5
Uridine, 5'-O-(methoxymethyl)-2',3'-O-(1-methylethylidene)- chemical structure, C14H20N2O7, CAS 80614-78-4
Uridine, 5'-O-(methoxymethyl)-2',3'-O-(1-methylethylidene)-
CAS 80614-78-4C14H20N2O7