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Murcko scaffold

Ring system with 2 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
15
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)Nc1cnccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)Nc1cnccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1-(2,4-Difluorophenyl)-3-pyrazin-2-ylurea chemical structure, C11H8F2N4O, CAS 706768-52-7
1-(2,4-Difluorophenyl)-3-pyrazin-2-ylurea
CAS 706768-52-7C11H8F2N4O
1-(4-Bromo-2-chlorophenyl)-3-pyrazin-2-ylurea chemical structure, C11H8BrClN4O, CAS 708216-06-2
1-(4-Bromo-2-chlorophenyl)-3-pyrazin-2-ylurea
CAS 708216-06-2C11H8BrClN4O
1-(3-Chlorophenyl)-3-pyrazin-2-ylurea chemical structure, C11H9ClN4O, CAS 71306-99-5
1-(3-Chlorophenyl)-3-pyrazin-2-ylurea
CAS 71306-99-5C11H9ClN4O
1-(2-Chlorophenyl)-3-pyrazin-2-ylurea chemical structure, C11H9ClN4O, CAS 712301-21-8
1-(2-Chlorophenyl)-3-pyrazin-2-ylurea
CAS 712301-21-8C11H9ClN4O
1-(4-Methoxyphenyl)-3-pyrazin-2-ylurea chemical structure, C12H12N4O2, CAS 631863-28-0
1-(4-Methoxyphenyl)-3-pyrazin-2-ylurea
CAS 631863-28-0C12H12N4O2
1-(3-Methoxyphenyl)-3-pyrazin-2-ylurea chemical structure, C12H12N4O2, CAS 631863-22-4
1-(3-Methoxyphenyl)-3-pyrazin-2-ylurea
CAS 631863-22-4C12H12N4O2
1-(3-Chloro-4-methylphenyl)-3-pyrazin-2-ylurea chemical structure, C12H11ClN4O, CAS 889588-71-0
1-(3-Chloro-4-methylphenyl)-3-pyrazin-2-ylurea
CAS 889588-71-0C12H11ClN4O
1-(2,3-Dichlorophenyl)-3-pyrazin-2-ylurea chemical structure, C11H8Cl2N4O, CAS 893333-52-3
1-(2,3-Dichlorophenyl)-3-pyrazin-2-ylurea
CAS 893333-52-3C11H8Cl2N4O
N-{2-[2-(Dimethylamino)ethoxy]-5-methylphenyl}-N'-pyrazin-2-ylurea chemical structure, C16H21N5O2, CAS 457098-41-8
N-{2-[2-(Dimethylamino)ethoxy]-5-methylphenyl}-N'-pyrazin-2-ylurea
CAS 457098-41-8C16H21N5O2
Chk inhibitor XL844 chemical structure, C14H17N5O2, CAS 631864-00-1
Chk inhibitor XL844
CAS 631864-00-1C14H17N5O2
1-(3-Fluoro-4-methylphenyl)-3-pyrazin-2-ylurea chemical structure, C12H11FN4O, CAS 906789-62-6
1-(3-Fluoro-4-methylphenyl)-3-pyrazin-2-ylurea
CAS 906789-62-6C12H11FN4O
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-pyrazin-2-ylurea chemical structure, C13H13ClN4O3, CAS 196700-52-4
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-pyrazin-2-ylurea
CAS 196700-52-4C13H13ClN4O3
N-(5-Chloro-2-hydroxyphenyl)-n'-(5-cyano-2-pyrazinyl)urea chemical structure, C12H8ClN5O2, CAS 660851-46-7
N-(5-Chloro-2-hydroxyphenyl)-n'-(5-cyano-2-pyrazinyl)urea
CAS 660851-46-7C12H8ClN5O2
Carbonic anhydrase inhibitor 10 chemical structure, C14H17N5O3S, CAS 2883453-30-1
Carbonic anhydrase inhibitor 10
CAS 2883453-30-1C14H17N5O3S
1-(6-Cyanopyrazin-2-yl)-3-phenylurea chemical structure, C12H9N5O, CAS 2839144-50-0
1-(6-Cyanopyrazin-2-yl)-3-phenylurea
CAS 2839144-50-0C12H9N5O