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Murcko scaffold

1,2,3,4-Tetrahydro-2,7-naphthyridine scaffold

124 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
124
With full pages
16
Scaffold SMILES

c1cc2c(cn1)CNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-2,7-naphthyridine page
Murcko scaffold c1cc2c(cn1)CNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 124 chemicals

1,3-Dichloro-7-ethyl-5,6,7,8-tetrahydro-[2,7]naphthyridine-4-carbonitrile chemical structure, C11H11Cl2N3, CAS 372175-41-2
1,3-Dichloro-7-ethyl-5,6,7,8-tetrahydro-[2,7]naphthyridine-4-carbonitrile
CAS 372175-41-2C11H11Cl2N3
1,3-Dichloro-7-methyl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile chemical structure, C10H9Cl2N3, CAS 372089-74-2
1,3-Dichloro-7-methyl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile
CAS 372089-74-2C10H9Cl2N3
1,2,3,4-Tetrahydro-2,7-naphthyridine chemical structure, C8H10N2, CAS 108749-08-2
1,2,3,4-Tetrahydro-2,7-naphthyridine
CAS 108749-08-2C8H10N2
2-Methyl-3,4-dihydro-1H-2,7-naphthyridine chemical structure, C9H12N2, CAS 13479-44-2
2-Methyl-3,4-dihydro-1H-2,7-naphthyridine
CAS 13479-44-2C9H12N2
Ethyl 3,4-dihydro-2,7-naphthyridine-2(1H)-carboxylate chemical structure, C11H14N2O2, CAS 449175-31-9
Ethyl 3,4-dihydro-2,7-naphthyridine-2(1H)-carboxylate
CAS 449175-31-9C11H14N2O2
2-tert-Butyl-6-methoxy-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C13H20N2O, CAS 893567-16-3
2-tert-Butyl-6-methoxy-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 893567-16-3C13H20N2O
1,2,3,4-Tetrahydro-2,7-naphthyridine hydrochloride chemical structure, C8H11ClN2, CAS 1354940-72-9
1,2,3,4-Tetrahydro-2,7-naphthyridine hydrochloride
CAS 1354940-72-9C8H11ClN2
1-(3,4-Dihydro-2,7-naphthyridin-2(1H)-yl)ethanone chemical structure, C10H12N2O, CAS 1956377-18-6
1-(3,4-Dihydro-2,7-naphthyridin-2(1H)-yl)ethanone
CAS 1956377-18-6C10H12N2O
6-Methoxy-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C9H12N2O, CAS 893566-81-9
6-Methoxy-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 893566-81-9C9H12N2O
tert-Butyl 5-[amino(hydroxyimino)methyl]-6-methyl-3,4-dihydro[2,7]naphthyridine-2(1H)-carboxylate chemical structure, C15H22N4O3, CAS 1353519-45-5
tert-Butyl 5-[amino(hydroxyimino)methyl]-6-methyl-3,4-dihydro[2,7]naphthyridine-2(1H)-carboxylate
CAS 1353519-45-5C15H22N4O3
tert-Butyl 5-(aminocarbonyl)-6-methyl-3,4-dihydro[2,7]naphthyridine-2(1H)-carboxylate chemical structure, C15H21N3O3, CAS 1353502-95-0
tert-Butyl 5-(aminocarbonyl)-6-methyl-3,4-dihydro[2,7]naphthyridine-2(1H)-carboxylate
CAS 1353502-95-0C15H21N3O3
1-Methyl-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C9H12N2, CAS 1176415-50-1
1-Methyl-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1176415-50-1C9H12N2
5,6,7,8-Tetrahydro-2,7-naphthyridin-1-amine chemical structure, C8H11N3, CAS 1795501-20-0
5,6,7,8-Tetrahydro-2,7-naphthyridin-1-amine
CAS 1795501-20-0C8H11N3
6-Methyl-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C9H12N2, CAS 112072-10-3
6-Methyl-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 112072-10-3C9H12N2
1,2,3,4-Tetrahydro-2,7-naphthyridine dihydrochloride chemical structure, C8H12Cl2N2, CAS 449175-32-0
1,2,3,4-Tetrahydro-2,7-naphthyridine dihydrochloride
CAS 449175-32-0C8H12Cl2N2
2,7-Naphthyridine-3-carboxylic acid, 1,2,3,4-tetrahydro- chemical structure, C9H10N2O2, CAS 1256784-99-2
2,7-Naphthyridine-3-carboxylic acid, 1,2,3,4-tetrahydro-
CAS 1256784-99-2C9H10N2O2
7-(tert-Butoxycarbonyl)-3-chloro-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carboxylic acid chemical structure, C14H17ClN2O4, CAS 1250998-50-5
7-(tert-Butoxycarbonyl)-3-chloro-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carboxylic acid
CAS 1250998-50-5C14H17ClN2O4
tert-Butyl 5-(aminomethyl)-3,4-dihydro-2,7-naphthyridine-2(1H)-carboxylate chemical structure, C14H21N3O2, CAS 1250999-86-0
tert-Butyl 5-(aminomethyl)-3,4-dihydro-2,7-naphthyridine-2(1H)-carboxylate
CAS 1250999-86-0C14H21N3O2
6-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C8H9ClN2, CAS 1196151-85-5
6-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1196151-85-5C8H9ClN2
6-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C9H9F3N2, CAS 1196155-32-4
6-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1196155-32-4C9H9F3N2
8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C8H9ClN2, CAS 1256812-56-2
8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1256812-56-2C8H9ClN2
5-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C8H9BrN2, CAS 1369359-38-5
5-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1369359-38-5C8H9BrN2
6-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C8H9BrN2, CAS 1393567-67-3
6-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1393567-67-3C8H9BrN2
8-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine chemical structure, C8H9BrN2, CAS 1393568-73-4
8-Bromo-1,2,3,4-tetrahydro-2,7-naphthyridine
CAS 1393568-73-4C8H9BrN2