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Murcko scaffold

Ring system with 4 rings and 23 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
17
With full pages
8
Scaffold SMILES

O=c1c2ccccc2nc(-c2ccccc2)n1-c1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2nc(-c2ccccc2)n1-c1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-(4-Methylpyridin-2-yl)-2-phenylquinazolin-4-one chemical structure, C20H15N3O, CAS 378758-52-2
3-(4-Methylpyridin-2-yl)-2-phenylquinazolin-4-one
CAS 378758-52-2C20H15N3O
2-(4-Methylphenyl)-3-(4-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O, CAS 380590-07-8
2-(4-Methylphenyl)-3-(4-methylpyridin-2-yl)quinazolin-4-one
CAS 380590-07-8C21H17N3O
2-(4-Methoxyphenyl)-3-(4-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O2, CAS 381702-60-9
2-(4-Methoxyphenyl)-3-(4-methylpyridin-2-yl)quinazolin-4-one
CAS 381702-60-9C21H17N3O2
3-(3-Methylpyridin-2-yl)-2-phenylquinazolin-4(3H)-one chemical structure, C20H15N3O, CAS 364338-20-5
3-(3-Methylpyridin-2-yl)-2-phenylquinazolin-4(3H)-one
CAS 364338-20-5C20H15N3O
3-(6-Methylpyridin-2-yl)-2-phenylquinazolin-4-one chemical structure, C20H15N3O, CAS 332911-20-3
3-(6-Methylpyridin-2-yl)-2-phenylquinazolin-4-one
CAS 332911-20-3C20H15N3O
3-Pyridin-2-yl-2-p-tolyl-3H-quinazolin-4-one chemical structure, C20H15N3O, CAS 6055-75-0
3-Pyridin-2-yl-2-p-tolyl-3H-quinazolin-4-one
CAS 6055-75-0C20H15N3O
2-(4-Methylphenyl)-3-(3-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O, CAS 332911-23-6
2-(4-Methylphenyl)-3-(3-methylpyridin-2-yl)quinazolin-4-one
CAS 332911-23-6C21H17N3O
2-(4-Methylphenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O, CAS 332911-24-7
2-(4-Methylphenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one
CAS 332911-24-7C21H17N3O
2-(4-Methoxyphenyl)-3-pyridin-2-ylquinazolin-4-one chemical structure, C20H15N3O2, CAS 364742-30-3
2-(4-Methoxyphenyl)-3-pyridin-2-ylquinazolin-4-one
CAS 364742-30-3C20H15N3O2
2-(4-Methoxyphenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O2, CAS 381705-32-4
2-(4-Methoxyphenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one
CAS 381705-32-4C21H17N3O2
2-(4-Methoxyphenyl)-3-(3-methylpyridin-2-yl)quinazolin-4-one chemical structure, C21H17N3O2, CAS 380591-57-1
2-(4-Methoxyphenyl)-3-(3-methylpyridin-2-yl)quinazolin-4-one
CAS 380591-57-1C21H17N3O2
2-(2,4-Dichlorophenyl)-3-(4-methylpyridin-2-yl)quinazolin-4(3H)-one chemical structure, C20H13Cl2N3O, CAS 381198-11-4
2-(2,4-Dichlorophenyl)-3-(4-methylpyridin-2-yl)quinazolin-4(3H)-one
CAS 381198-11-4C20H13Cl2N3O
2-(2,4-Dichlorophenyl)-3-(3-methylpyridin-2-yl)quinazolin-4(3H)-one chemical structure, C20H13Cl2N3O, CAS 380592-97-2
2-(2,4-Dichlorophenyl)-3-(3-methylpyridin-2-yl)quinazolin-4(3H)-one
CAS 380592-97-2C20H13Cl2N3O
2-(2,4-Dichlorophenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one chemical structure, C20H13Cl2N3O, CAS 378776-97-7
2-(2,4-Dichlorophenyl)-3-(6-methylpyridin-2-yl)quinazolin-4-one
CAS 378776-97-7C20H13Cl2N3O
3-(5-Bromopyridin-2-yl)-2-(4-methylphenyl)quinazolin-4-one chemical structure, C20H14BrN3O, CAS 378213-91-3
3-(5-Bromopyridin-2-yl)-2-(4-methylphenyl)quinazolin-4-one
CAS 378213-91-3C20H14BrN3O
3-(5-Bromopyridin-2-yl)-2-phenylquinazolin-4-one chemical structure, C19H12BrN3O, CAS 364626-53-9
3-(5-Bromopyridin-2-yl)-2-phenylquinazolin-4-one
CAS 364626-53-9C19H12BrN3O
3-(5-Bromopyridin-2-yl)-2-(2,4-dichlorophenyl)quinazolin-4-one chemical structure, C19H10BrCl2N3O, CAS 380164-80-7
3-(5-Bromopyridin-2-yl)-2-(2,4-dichlorophenyl)quinazolin-4-one
CAS 380164-80-7C19H10BrCl2N3O