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Murcko scaffold

2,3-Diphenylpyrido[2,3-b]pyrazine scaffold

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
13
With full pages
2
Scaffold SMILES

c1ccc(-c2nc3cccnc3nc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Diphenylpyrido[2,3-b]pyrazine page
Murcko scaffold c1ccc(-c2nc3cccnc3nc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

8-Ethoxy-2,3-diphenylpyrido[2,3-b]pyrazin-6-amine chemical structure, C21H18N4O, CAS 16336-04-2
8-Ethoxy-2,3-diphenylpyrido[2,3-b]pyrazin-6-amine
CAS 16336-04-2C21H18N4O
8-N-[5-(Diethylamino)pentan-2-yl]-2,3-diphenylpyrido[2,3-b]pyrazine-6,8-diamine chemical structure, C28H34N6, CAS 19270-45-2
8-N-[5-(Diethylamino)pentan-2-yl]-2,3-diphenylpyrido[2,3-b]pyrazine-6,8-diamine
CAS 19270-45-2C28H34N6
Ethyl N-[8-[5-(diethylamino)pentan-2-ylamino]-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl]carbamate chemical structure, C31H38N6O2, CAS 19254-73-0
Ethyl N-[8-[5-(diethylamino)pentan-2-ylamino]-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl]carbamate
CAS 19254-73-0C31H38N6O2
Ethyl N-[2,3-bis(4-chlorophenyl)-8-[5-(diethylamino)pentan-2-ylamino]pyrido[2,3-b]pyrazin-6-yl]carbamate chemical structure, C31H36Cl2N6O2, CAS 21271-76-1
Ethyl N-[2,3-bis(4-chlorophenyl)-8-[5-(diethylamino)pentan-2-ylamino]pyrido[2,3-b]pyrazin-6-yl]carbamate
CAS 21271-76-1C31H36Cl2N6O2
2,3-Bis(4-chlorophenyl)-8-N-[5-(diethylamino)pentan-2-yl]pyrido[2,3-b]pyrazine-6,8-diamine chemical structure, C28H32Cl2N6, CAS 21271-77-2
2,3-Bis(4-chlorophenyl)-8-N-[5-(diethylamino)pentan-2-yl]pyrido[2,3-b]pyrazine-6,8-diamine
CAS 21271-77-2C28H32Cl2N6
7-Nitro-2,3-diphenylpyrido[2,3-b]pyrazine chemical structure, C19H12N4O2, CAS 887571-86-0
7-Nitro-2,3-diphenylpyrido[2,3-b]pyrazine
CAS 887571-86-0C19H12N4O2
2,3-Diphenylpyrido[2,3-b]pyrazine chemical structure, C19H13N3, CAS 1232-99-1
2,3-Diphenylpyrido[2,3-b]pyrazine
CAS 1232-99-1C19H13N3
2,3-Bis(3-bromophenyl)pyrido[2,3-b]pyrazine chemical structure, C19H11Br2N3, CAS 887578-13-4
2,3-Bis(3-bromophenyl)pyrido[2,3-b]pyrazine
CAS 887578-13-4C19H11Br2N3
2,3-Bis(3,4,5-trimethoxyphenyl)pyrido[2,3-b]pyrazine-6,8-diamine chemical structure, C25H27N5O6, CAS 28642-79-7
2,3-Bis(3,4,5-trimethoxyphenyl)pyrido[2,3-b]pyrazine-6,8-diamine
CAS 28642-79-7C25H27N5O6
2,3-Bis(4-methylphenyl)pyrido[2,3-b]pyrazine chemical structure, C21H17N3, CAS 361149-71-5
2,3-Bis(4-methylphenyl)pyrido[2,3-b]pyrazine
CAS 361149-71-5C21H17N3
Ethyl N-[8-(2-diethylaminoethylamino)-2,3-diphenyl-pyrido[2,3-b]pyrazin-6-yl]carbamate chemical structure, C28H32N6O2, CAS 1347749-94-3
Ethyl N-[8-(2-diethylaminoethylamino)-2,3-diphenyl-pyrido[2,3-b]pyrazin-6-yl]carbamate
CAS 1347749-94-3C28H32N6O2
Ethyl (8-((2-(dimethylamino)ethyl)amino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl)carbamate chemical structure, C26H28N6O2, CAS 1347749-97-6
Ethyl (8-((2-(dimethylamino)ethyl)amino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl)carbamate
CAS 1347749-97-6C26H28N6O2
Pyrido[2,3-b]pyrazine, 8-azido-2,3-diphenyl- chemical structure, C19H12N6, CAS 1305317-33-2
Pyrido[2,3-b]pyrazine, 8-azido-2,3-diphenyl-
CAS 1305317-33-2C19H12N6