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Murcko scaffold

2,3-Diphenyl-4(3H)-quinazolinone scaffold

65 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
65
With full pages
12
Scaffold SMILES

O=c1c2ccccc2nc(-c2ccccc2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Diphenyl-4(3H)-quinazolinone page
Murcko scaffold O=c1c2ccccc2nc(-c2ccccc2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

2-(3'-(Methoxycarbonylamino)phenyl)-3-phenyl-6-methoxycarbonylamino-4-(3H)-quinazolone chemical structure, C24H20N4O5, CAS 37799-31-8
2-(3'-(Methoxycarbonylamino)phenyl)-3-phenyl-6-methoxycarbonylamino-4-(3H)-quinazolone
CAS 37799-31-8C24H20N4O5
2,3-Diphenyl-4(3H)-quinazolinone chemical structure, C20H14N2O, CAS 22686-82-4
2,3-Diphenyl-4(3H)-quinazolinone
CAS 22686-82-4C20H14N2O
2-(4-Nitrophenyl)-3-phenylquinazolin-4-one chemical structure, C20H13N3O3, CAS 36567-86-9
2-(4-Nitrophenyl)-3-phenylquinazolin-4-one
CAS 36567-86-9C20H13N3O3
4(3H)-Quinazolinone, 3-(4-methoxyphenyl)-2-phenyl- chemical structure, C21H16N2O2, CAS 37856-17-0
4(3H)-Quinazolinone, 3-(4-methoxyphenyl)-2-phenyl-
CAS 37856-17-0C21H16N2O2
3-(2-Nitrophenyl)-2-phenylquinazolin-4-one chemical structure, C20H13N3O3, CAS 361185-53-7
3-(2-Nitrophenyl)-2-phenylquinazolin-4-one
CAS 361185-53-7C20H13N3O3
4(3H)-Quinazolinone, 3-(4-hydroxyphenyl)-2-phenyl- chemical structure, C20H14N2O2, CAS 37856-23-8
4(3H)-Quinazolinone, 3-(4-hydroxyphenyl)-2-phenyl-
CAS 37856-23-8C20H14N2O2
3-(3-Hydroxyphenyl)-2-phenylquinazolin-4-one chemical structure, C20H14N2O2, CAS 361185-54-8
3-(3-Hydroxyphenyl)-2-phenylquinazolin-4-one
CAS 361185-54-8C20H14N2O2
3-(2-Hydroxyphenyl)-2-phenylquinazolin-4-one chemical structure, C20H14N2O2, CAS 361185-55-9
3-(2-Hydroxyphenyl)-2-phenylquinazolin-4-one
CAS 361185-55-9C20H14N2O2
2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one chemical structure, C20H13ClN2O2, CAS 375356-01-7
2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one
CAS 375356-01-7C20H13ClN2O2
3-(3-Methoxyphenyl)-2-(4-methylphenyl)quinazolin-4-one chemical structure, C22H18N2O2, CAS 380594-77-4
3-(3-Methoxyphenyl)-2-(4-methylphenyl)quinazolin-4-one
CAS 380594-77-4C22H18N2O2
4(3H)-Quinazolinone, 3-(4-methylphenyl)-2-phenyl- chemical structure, C21H16N2O, CAS 37856-14-7
4(3H)-Quinazolinone, 3-(4-methylphenyl)-2-phenyl-
CAS 37856-14-7C21H16N2O
3-(2-Methoxyphenyl)-2-phenyl-4(3H)-quinazolinone chemical structure, C21H16N2O2, CAS 37856-18-1
3-(2-Methoxyphenyl)-2-phenyl-4(3H)-quinazolinone
CAS 37856-18-1C21H16N2O2
2-(2-Fluorophenyl)-3-(2-methoxyphenyl)quinazolin-4-one chemical structure, C21H15FN2O2, CAS 313969-52-7
2-(2-Fluorophenyl)-3-(2-methoxyphenyl)quinazolin-4-one
CAS 313969-52-7C21H15FN2O2
3-(2,3-Dimethylphenyl)-2-phenylquinazolin-4-one chemical structure, C22H18N2O, CAS 332033-21-3
3-(2,3-Dimethylphenyl)-2-phenylquinazolin-4-one
CAS 332033-21-3C22H18N2O
3-(4-Fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-one chemical structure, C21H15FN2O2, CAS 672269-47-5
3-(4-Fluorophenyl)-2-(4-methoxyphenyl)quinazolin-4-one
CAS 672269-47-5C21H15FN2O2
Benzoic acid, 4-(4-oxo-2-phenyl-3(4H)-quinazolinyl)- chemical structure, C21H14N2O3, CAS 37856-24-9
Benzoic acid, 4-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-
CAS 37856-24-9C21H14N2O3
2-(2-Chlorophenyl)-3-(4-methylphenyl)quinazolin-4-one chemical structure, C21H15ClN2O, CAS 374920-51-1
2-(2-Chlorophenyl)-3-(4-methylphenyl)quinazolin-4-one
CAS 374920-51-1C21H15ClN2O
3-(o-Tolyl)-2-(p-tolyl)quinazolin-4(3H)-one chemical structure, C22H18N2O, CAS 380875-79-6
3-(o-Tolyl)-2-(p-tolyl)quinazolin-4(3H)-one
CAS 380875-79-6C22H18N2O
Ethyl 4-(4-oxo-2-phenylquinazolin-3-yl)benzoate chemical structure, C23H18N2O3, CAS 342384-34-3
Ethyl 4-(4-oxo-2-phenylquinazolin-3-yl)benzoate
CAS 342384-34-3C23H18N2O3
Ethyl 4-[2-(4-methylphenyl)-4-oxoquinazolin-3-yl]benzoate chemical structure, C24H20N2O3, CAS 380646-38-8
Ethyl 4-[2-(4-methylphenyl)-4-oxoquinazolin-3-yl]benzoate
CAS 380646-38-8C24H20N2O3
2-(4-Methylphenyl)-3-(3-nitrophenyl)quinazolin-4-one chemical structure, C21H15N3O3, CAS 378753-54-9
2-(4-Methylphenyl)-3-(3-nitrophenyl)quinazolin-4-one
CAS 378753-54-9C21H15N3O3
3-(4-Chlorophenyl)-2-(2-fluorophenyl)quinazolin-4-one chemical structure, C20H12ClFN2O, CAS 314052-01-2
3-(4-Chlorophenyl)-2-(2-fluorophenyl)quinazolin-4-one
CAS 314052-01-2C20H12ClFN2O
3-(2-Chlorophenyl)-2-(2-fluorophenyl)quinazolin-4-one chemical structure, C20H12ClFN2O, CAS 6050-24-4
3-(2-Chlorophenyl)-2-(2-fluorophenyl)quinazolin-4-one
CAS 6050-24-4C20H12ClFN2O
2-(4-Methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]quinazolin-4-one chemical structure, C22H15F3N2O2, CAS 690693-05-1
2-(4-Methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]quinazolin-4-one
CAS 690693-05-1C22H15F3N2O2