CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
20
With full pages
4
Scaffold SMILES

O=C(CSc1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-{[N-(2-Phenylethyl)carbamoyl]methylthio}benzoic acid chemical structure, C17H17NO3S, CAS 380438-09-5
2-{[N-(2-Phenylethyl)carbamoyl]methylthio}benzoic acid
CAS 380438-09-5C17H17NO3S
N-[2-(4-Fluorophenyl)ethyl]-2-(4-methylphenyl)sulfanylacetamide chemical structure, C17H18FNOS, CAS 701217-80-3
N-[2-(4-Fluorophenyl)ethyl]-2-(4-methylphenyl)sulfanylacetamide
CAS 701217-80-3C17H18FNOS
2-(4-Chlorophenyl)sulfanyl-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C17H18ClNO2S, CAS 367914-78-1
2-(4-Chlorophenyl)sulfanyl-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 367914-78-1C17H18ClNO2S
2-(4-Methylphenyl)sulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide chemical structure, C17H20N2O3S2, CAS 701230-65-1
2-(4-Methylphenyl)sulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
CAS 701230-65-1C17H20N2O3S2
2-Phenylsulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide chemical structure, C16H18N2O3S2, CAS 25202-66-8
2-Phenylsulfanyl-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
CAS 25202-66-8C16H18N2O3S2
2-(4-Chlorophenyl)sulfanyl-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C18H20ClNO3S, CAS 3341-23-9
2-(4-Chlorophenyl)sulfanyl-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 3341-23-9C18H20ClNO3S
2-(4-Chlorophenylthio)-N-(2-phenylethyl)ethanamide chemical structure, C16H16ClNOS, CAS 14617-35-7
2-(4-Chlorophenylthio)-N-(2-phenylethyl)ethanamide
CAS 14617-35-7C16H16ClNOS
N-[2-(4-Chlorophenyl)ethyl]-2-(4-fluorophenyl)sulfanylacetamide chemical structure, C16H15ClFNOS, CAS 764700-18-7
N-[2-(4-Chlorophenyl)ethyl]-2-(4-fluorophenyl)sulfanylacetamide
CAS 764700-18-7C16H15ClFNOS
2-[({[2-(3,4-Dimethoxyphenyl)ethyl]carbamoyl}methyl)sulfanyl]benzoic acid chemical structure, C19H21NO5S, CAS 850021-36-2
2-[({[2-(3,4-Dimethoxyphenyl)ethyl]carbamoyl}methyl)sulfanyl]benzoic acid
CAS 850021-36-2C19H21NO5S
2-[(4-Chlorophenyl)sulfanyl]-N-(2-phenylethyl)propanamide chemical structure, C17H18ClNOS, CAS 332039-40-4
2-[(4-Chlorophenyl)sulfanyl]-N-(2-phenylethyl)propanamide
CAS 332039-40-4C17H18ClNOS
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-phenylsulfanylpropanamide chemical structure, C19H23NO3S, CAS 700851-94-1
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-phenylsulfanylpropanamide
CAS 700851-94-1C19H23NO3S
2-((4-Fluorophenyl)thio)-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)acetamide chemical structure, C17H15F4NO2S, CAS 1351649-49-4
2-((4-Fluorophenyl)thio)-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)acetamide
CAS 1351649-49-4C17H15F4NO2S
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)-2-((4-fluorophenyl)thio)acetamide chemical structure, C18H21FN2O2S, CAS 1421485-58-6
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)-2-((4-fluorophenyl)thio)acetamide
CAS 1421485-58-6C18H21FN2O2S
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-(o-tolyl)ethyl)acetamide chemical structure, C18H20FNO2S, CAS 1797898-11-3
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-(o-tolyl)ethyl)acetamide
CAS 1797898-11-3C18H20FNO2S
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-phenylbutyl)acetamide chemical structure, C19H22FNO2S, CAS 1796951-34-2
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-phenylbutyl)acetamide
CAS 1796951-34-2C19H22FNO2S
N-(2-(3-Fluorophenyl)-2-methoxyethyl)-2-((4-fluorophenyl)thio)acetamide chemical structure, C17H17F2NO2S, CAS 1797876-54-0
N-(2-(3-Fluorophenyl)-2-methoxyethyl)-2-((4-fluorophenyl)thio)acetamide
CAS 1797876-54-0C17H17F2NO2S
2-((4-Fluorophenyl)thio)-N-(2-(2-hydroxyethoxy)-2-(p-tolyl)ethyl)acetamide chemical structure, C19H22FNO3S, CAS 1795485-24-3
2-((4-Fluorophenyl)thio)-N-(2-(2-hydroxyethoxy)-2-(p-tolyl)ethyl)acetamide
CAS 1795485-24-3C19H22FNO3S
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-(2-methoxyphenyl)ethyl)acetamide chemical structure, C18H20FNO3S, CAS 1795299-65-8
2-((4-Fluorophenyl)thio)-N-(2-methoxy-2-(2-methoxyphenyl)ethyl)acetamide
CAS 1795299-65-8C18H20FNO3S
N-(2-(2-Chlorophenyl)-2-methoxyethyl)-2-((4-fluorophenyl)thio)acetamide chemical structure, C17H17ClFNO2S, CAS 1795442-29-3
N-(2-(2-Chlorophenyl)-2-methoxyethyl)-2-((4-fluorophenyl)thio)acetamide
CAS 1795442-29-3C17H17ClFNO2S
N-(2-(3-Chlorophenyl)-2-methoxypropyl)-2-((4-fluorophenyl)thio)acetamide chemical structure, C18H19ClFNO2S, CAS 1795088-69-5
N-(2-(3-Chlorophenyl)-2-methoxypropyl)-2-((4-fluorophenyl)thio)acetamide
CAS 1795088-69-5C18H19ClFNO2S