Murcko scaffold
Ring system with 4 rings and 21 atoms
47 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 47
- With full pages
- 1
Scaffold SMILES
O=C(Nc1nc2ccc3scnc3c2s1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 47 of 47 chemicals
![4-(Dimethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H16N4O3S3, CAS 361482-08-8](/s/RXXFSWFKNAVPSA-UHFFFAOYSA-N.svg)
4-(Dimethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361482-08-8C18H16N4O3S3
![4-(Dipropylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C22H24N4O3S3, CAS 361482-09-9](/s/QMRBIBYOKMUPSC-UHFFFAOYSA-N.svg)
4-(Dipropylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361482-09-9C22H24N4O3S3
![4-[Bis(2-methylpropyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C24H28N4O3S3, CAS 361171-28-0](/s/MWXFNICEXWXSML-UHFFFAOYSA-N.svg)
4-[Bis(2-methylpropyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361171-28-0C24H28N4O3S3
![2,6-Difluoro-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)benzamide chemical structure, C16H9F2N3OS2, CAS 394227-81-7](/s/BLFFYSATYNQRCI-UHFFFAOYSA-N.svg)
2,6-Difluoro-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)benzamide
CAS 394227-81-7C16H9F2N3OS2
![N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-nitrobenzamide chemical structure, C16H10N4O3S2, CAS 476631-69-3](/s/UQOPUUCPVNESGW-UHFFFAOYSA-N.svg)
N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-nitrobenzamide
CAS 476631-69-3C16H10N4O3S2
![Methyl 4-[(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)carbamoyl]benzoate chemical structure, C18H13N3O3S2, CAS 361482-18-0](/s/FEVSLUOPMFFTMF-UHFFFAOYSA-N.svg)
Methyl 4-[(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)carbamoyl]benzoate
CAS 361482-18-0C18H13N3O3S2
![4-(Dibutylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C24H28N4O3S3, CAS 683767-65-9](/s/BQJHTZXWMVYKTO-UHFFFAOYSA-N.svg)
4-(Dibutylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 683767-65-9C24H28N4O3S3
![3,5-Dimethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H15N3O3S2, CAS 361171-20-2](/s/ZTRDQXDNAHDTKX-UHFFFAOYSA-N.svg)
3,5-Dimethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361171-20-2C18H15N3O3S2
![3,5-Dichloro-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C16H9Cl2N3OS2, CAS 476642-10-1](/s/JZMZKJFUIRNCSS-UHFFFAOYSA-N.svg)
3,5-Dichloro-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 476642-10-1C16H9Cl2N3OS2
![4-tert-Butyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C20H19N3OS2, CAS 476642-08-7](/s/IDOMJYQMZDRBMF-UHFFFAOYSA-N.svg)
4-tert-Butyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 476642-08-7C20H19N3OS2
![4-Cyano-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C17H10N4OS2, CAS 441290-38-6](/s/FJZDQWPWQNNLRT-UHFFFAOYSA-N.svg)
4-Cyano-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 441290-38-6C17H10N4OS2
![N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C16H11N3OS2, CAS 394227-39-5](/s/OFRCOCYLLBENGX-UHFFFAOYSA-N.svg)
N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 394227-39-5C16H11N3OS2
![4-Methyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C17H13N3OS2, CAS 361482-00-0](/s/OUGAXMZNUZGVKT-UHFFFAOYSA-N.svg)
4-Methyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361482-00-0C17H13N3OS2
![2-Chloro-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)benzamide chemical structure, C16H10ClN3OS2, CAS 361482-02-2](/s/KNMDFRBZLUGBDR-UHFFFAOYSA-N.svg)
2-Chloro-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)benzamide
CAS 361482-02-2C16H10ClN3OS2
![4-(Diethylamino)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C20H20N4OS2, CAS 361173-02-6](/s/GJKICHRUVVWPFS-UHFFFAOYSA-N.svg)
4-(Diethylamino)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361173-02-6C20H20N4OS2
![4-(Diethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C20H20N4O3S3, CAS 361482-03-3](/s/ASROBPFXYDTXDG-UHFFFAOYSA-N.svg)
4-(Diethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361482-03-3C20H20N4O3S3
![4-[Butyl(methyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C21H22N4O3S3, CAS 683767-66-0](/s/HXZHMFUYLLQZEC-UHFFFAOYSA-N.svg)
4-[Butyl(methyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 683767-66-0C21H22N4O3S3
![4-Chloro-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C16H10ClN3OS2, CAS 361482-01-1](/s/UKOQHTCSVVRJRU-UHFFFAOYSA-N.svg)
4-Chloro-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361482-01-1C16H10ClN3OS2
![3-Bromo-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C16H10BrN3OS2, CAS 476631-72-8](/s/LDRWFQNTWFUEBT-UHFFFAOYSA-N.svg)
3-Bromo-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 476631-72-8C16H10BrN3OS2
![2-Bromo-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C16H10BrN3OS2, CAS 476631-73-9](/s/SYAKNKDKRALJQK-UHFFFAOYSA-N.svg)
2-Bromo-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 476631-73-9C16H10BrN3OS2
![4-[Butyl(ethyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C22H24N4O3S3, CAS 500149-68-8](/s/JSYJGAXPILBSKZ-UHFFFAOYSA-N.svg)
4-[Butyl(ethyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 500149-68-8C22H24N4O3S3
![3-Methyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C17H13N3OS2, CAS 394227-42-0](/s/ZASKLEZMDLGGMF-UHFFFAOYSA-N.svg)
3-Methyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 394227-42-0C17H13N3OS2
![3,4-Dimethyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H15N3OS2, CAS 476631-85-3](/s/FAJXWMQRBYPJGB-UHFFFAOYSA-N.svg)
3,4-Dimethyl-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 476631-85-3C18H15N3OS2
![4-[Bis(2-methoxyethyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide chemical structure, C22H24N4O5S3, CAS 361171-27-9](/s/UJFCPTVYJBOINN-UHFFFAOYSA-N.svg)
4-[Bis(2-methoxyethyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide
CAS 361171-27-9C22H24N4O5S3
- 3-Methoxy-N-(7-methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)benzamide361482-05-5C17H13N3O2S2
- 4-(Dimethylamino)-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide477536-30-4C18H16N4OS2
- 4-Butoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide476642-12-3C20H19N3O2S2
- 4-[Bis(prop-2-enyl)sulfamoyl]-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide394228-11-6C22H20N4O3S3
- 2-Iodo-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide394228-05-8C16H10IN3OS2
- 4-Methoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide361482-04-4C17H13N3O2S2
- 3-Fluoro-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide476631-82-0C16H10FN3OS2
- 4-Ethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide394227-64-6C18H15N3O2S2
- N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-(trifluoromethyl)benzamide476642-18-9C17H10F3N3OS2
- N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-2-nitrobenzamide476631-70-6C16H10N4O3S2
- 2,4-Dimethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide361482-07-7C18H15N3O3S2
- 2,6-Dimethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide361482-19-1C18H15N3O3S2
- N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-4-propan-2-yloxybenzamide361170-94-7C19H17N3O2S2
- 2-Methoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide361482-06-6C17H13N3O2S2
- N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-4-nitrobenzamide394227-48-6C16H10N4O3S2
- N-(7-Methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-4-pentoxybenzamide477556-00-6C21H21N3O2S2
- 2,3-Dimethoxy-N-(7-methyl-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)benzamide903355-40-8C18H15N3O3S2
- N-{11-Methyl-3,10-dithia-5,12-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}-3-(methylsulfanyl)benzamide896338-72-0C17H13N3OS3
- N-(7-Methylbenzo[1,2-d:3,4-d']bis(thiazole)-2-yl)-4-(methylthio)benzamide896353-02-9C17H13N3OS3
- 2-Methanesulfonyl-N-{11-methyl-3,10-dithia-5,12-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}benzamide896365-65-4C17H13N3O3S3
- 3-Methanesulfonyl-N-{11-methyl-3,10-dithia-5,12-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}benzamide896290-27-0C17H13N3O3S3
- 4-Methanesulfonyl-N-{11-methyl-3,10-dithia-5,12-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}benzamide896343-66-1C17H13N3O3S3
- N-{11-Methyl-3,10-dithia-5,12-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}-3-(propane-2-sulfonyl)benzamide941992-99-0C19H17N3O3S3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc(OCc2nc3c4cn[nH]c4ncn3n2)cc1](/scaffold/ZWPUPVSBFYXDTN-UHFFFAOYSA-N/structure.svg)