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Murcko scaffold

Ring system with 4 rings and 21 atoms

74 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
74
With full pages
6
Scaffold SMILES

O=C(Nc1nc2ccc3ncsc3c2s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc2ccc3ncsc3c2s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 74 chemicals

4-Methyl-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C17H13N3OS2, CAS 325978-31-2
4-Methyl-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 325978-31-2C17H13N3OS2
2-Chloro-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-5-nitrobenzamide chemical structure, C16H9ClN4O3S2, CAS 391218-04-5
2-Chloro-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-5-nitrobenzamide
CAS 391218-04-5C16H9ClN4O3S2
N-{11-Methyl-3,12-dithia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,10-pentaen-4-yl}-4-nitrobenzamide chemical structure, C16H10N4O3S2, CAS 313403-73-5
N-{11-Methyl-3,12-dithia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,10-pentaen-4-yl}-4-nitrobenzamide
CAS 313403-73-5C16H10N4O3S2
3,4,5-Trimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C19H17N3O4S2, CAS 327038-71-1
3,4,5-Trimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 327038-71-1C19H17N3O4S2
4-(Diethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C20H20N4O3S3, CAS 361158-85-2
4-(Diethylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 361158-85-2C20H20N4O3S3
2-Methyl-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C17H13N3OS2, CAS 361158-82-9
2-Methyl-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 361158-82-9C17H13N3OS2
2-Bromo-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C16H10BrN3OS3, CAS 477503-32-5
2-Bromo-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-32-5C16H10BrN3OS3
4-(Dipropylsulfamoyl)-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C22H24N4O3S4, CAS 361173-14-0
4-(Dipropylsulfamoyl)-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 361173-14-0C22H24N4O3S4
N-(7-Methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-2-nitrobenzamide chemical structure, C16H10N4O3S2, CAS 361158-83-0
N-(7-Methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-2-nitrobenzamide
CAS 361158-83-0C16H10N4O3S2
4-Ethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C18H15N3O2S3, CAS 477503-45-0
4-Ethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-45-0C18H15N3O2S3
3,5-Dimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H15N3O3S2, CAS 313403-74-6
3,5-Dimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 313403-74-6C18H15N3O3S2
Methyl 4-[(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)carbamoyl]benzoate chemical structure, C18H13N3O3S3, CAS 361173-21-9
Methyl 4-[(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)carbamoyl]benzoate
CAS 361173-21-9C18H13N3O3S3
2,6-Dimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C18H15N3O3S2, CAS 500198-53-8
2,6-Dimethoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 500198-53-8C18H15N3O3S2
2-Methyl-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C17H13N3OS3, CAS 477503-23-4
2-Methyl-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-23-4C17H13N3OS3
2,4-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C18H15N3O3S3, CAS 361173-06-0
2,4-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 361173-06-0C18H15N3O3S3
N-(7-Methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-4-propan-2-yloxybenzamide chemical structure, C19H17N3O2S2, CAS 684232-45-9
N-(7-Methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-4-propan-2-yloxybenzamide
CAS 684232-45-9C19H17N3O2S2
N-(2-Methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-3-nitrobenzamide chemical structure, C16H10N4O3S3, CAS 477503-27-8
N-(2-Methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-3-nitrobenzamide
CAS 477503-27-8C16H10N4O3S3
4-tert-Butyl-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C20H19N3OS3, CAS 477503-28-9
4-tert-Butyl-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-28-9C20H19N3OS3
3,4-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C18H15N3O3S3, CAS 441290-73-9
3,4-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 441290-73-9C18H15N3O3S3
3-Bromo-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C16H10BrN3OS3, CAS 477503-33-6
3-Bromo-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-33-6C16H10BrN3OS3
4-(Dibutylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide chemical structure, C24H28N4O3S3, CAS 442556-84-5
4-(Dibutylsulfamoyl)-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide
CAS 442556-84-5C24H28N4O3S3
2,6-Difluoro-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C16H9F2N3OS3, CAS 477503-53-0
2,6-Difluoro-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 477503-53-0C16H9F2N3OS3
2,6-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide chemical structure, C18H15N3O3S3, CAS 441290-75-1
2,6-Dimethoxy-N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)benzamide
CAS 441290-75-1C18H15N3O3S3
N-(2-Methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-4-propan-2-yloxybenzamide chemical structure, C19H17N3O2S3, CAS 477503-71-2
N-(2-Methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-4-propan-2-yloxybenzamide
CAS 477503-71-2C19H17N3O2S3