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Murcko scaffold

Ring system with 3 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
7
With full pages
1
Scaffold SMILES

O=C1CCCC(C=Cc2cncnc2-c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(C=Cc2cncnc2-c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Rosuvastatin lactone chemical structure, C22H26FN3O5S, CAS 503610-43-3
Rosuvastatin lactone
CAS 503610-43-3C22H26FN3O5S
(3R,5R)-Rosuvastatin lactone chemical structure, C22H26FN3O5S, CAS 1422954-11-7
(3R,5R)-Rosuvastatin lactone
CAS 1422954-11-7C22H26FN3O5S
ent-Rosuvastatin Lactone chemical structure, C22H26FN3O5S
ent-Rosuvastatin Lactone
C22H26FN3O5S
N-Desmethyl rosuvastatin lactone chemical structure, C21H24FN3O5S, CAS 1797419-58-9
N-Desmethyl rosuvastatin lactone
CAS 1797419-58-9C21H24FN3O5S
5'-O-tert-Butyldimethylsilyl Rosuvastatin Lactone chemical structure, C28H40FN3O5SSi, CAS 1246832-82-5
5'-O-tert-Butyldimethylsilyl Rosuvastatin Lactone
CAS 1246832-82-5C28H40FN3O5SSi
rel-N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2R,4S)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide chemical structure, C22H26FN3O5S, CAS 615263-62-2
rel-N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2R,4S)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
CAS 615263-62-2C22H26FN3O5S
Rosuvastatin (2S,4S)-lactone chemical structure, C22H26FN3O5S, CAS 1809092-87-2
Rosuvastatin (2S,4S)-lactone
CAS 1809092-87-2C22H26FN3O5S