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Murcko scaffold

Ring system with 3 rings and 21 atoms

226 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
226
With full pages
15
Scaffold SMILES

O=C(Nc1ccccc1N1CCNCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCNCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 226 chemicals

2,5-Dichloro-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}benzamide chemical structure, C18H19Cl2N3O3S, CAS 724449-54-1
2,5-Dichloro-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}benzamide
CAS 724449-54-1C18H19Cl2N3O3S
3,4-Dichloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H19Cl2N3O3S, CAS 724449-55-2
3,4-Dichloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 724449-55-2C18H19Cl2N3O3S
2,4-Dichloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H19Cl2N3O3S, CAS 724449-56-3
2,4-Dichloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 724449-56-3C18H19Cl2N3O3S
3-Chloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20ClN3O3S, CAS 724449-58-5
3-Chloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 724449-58-5C18H20ClN3O3S
2-Chloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20ClN3O3S, CAS 724449-59-6
2-Chloro-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 724449-59-6C18H20ClN3O3S
2-Chloro-4-methyl-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H22ClN3O3S, CAS 724449-72-3
2-Chloro-4-methyl-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 724449-72-3C19H22ClN3O3S
2-Methoxy-3-methyl-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}benzamide chemical structure, C20H25N3O4S, CAS 717892-64-3
2-Methoxy-3-methyl-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}benzamide
CAS 717892-64-3C20H25N3O4S
3-Methyl-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H27N3O2, CAS 723753-04-6
3-Methyl-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 723753-04-6C22H27N3O2
4-Methoxy-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H27N3O3, CAS 723753-06-8
4-Methoxy-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 723753-06-8C22H27N3O3
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3-fluorobenzamide chemical structure, C19H21ClFN3O, CAS 723753-90-0
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3-fluorobenzamide
CAS 723753-90-0C19H21ClFN3O
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-4-fluorobenzamide chemical structure, C19H21ClFN3O, CAS 723753-91-1
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-4-fluorobenzamide
CAS 723753-91-1C19H21ClFN3O
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3-methylbenzamide chemical structure, C20H24ClN3O, CAS 714214-57-0
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3-methylbenzamide
CAS 714214-57-0C20H24ClN3O
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-4-cyano-2-fluorobenzamide chemical structure, C20H20ClFN4O, CAS 712291-48-0
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-4-cyano-2-fluorobenzamide
CAS 712291-48-0C20H20ClFN4O
2-Methyl-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O3S, CAS 718603-17-9
2-Methyl-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 718603-17-9C19H23N3O3S
2-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 797776-33-1
2-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 797776-33-1C21H24FN3O2
2-Chloro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24ClN3O2, CAS 797776-35-3
2-Chloro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 797776-35-3C21H24ClN3O2
3-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 708290-65-7
3-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 708290-65-7C21H24FN3O2
4-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 797776-39-7
4-Fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 797776-39-7C21H24FN3O2
2,4-Dichloro-N-[2-(4-isobutyryl-1-piperazinyl)phenyl]benzamide chemical structure, C21H23Cl2N3O2, CAS 708286-20-8
2,4-Dichloro-N-[2-(4-isobutyryl-1-piperazinyl)phenyl]benzamide
CAS 708286-20-8C21H23Cl2N3O2
4-Cyano-2-fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H23FN4O2, CAS 709004-52-4
4-Cyano-2-fluoro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 709004-52-4C22H23FN4O2
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3,4,5-trimethoxybenzamide chemical structure, C22H28ClN3O4, CAS 718602-86-9
N-[3-Chloro-2-(4-ethylpiperazin-1-yl)phenyl]-3,4,5-trimethoxybenzamide
CAS 718602-86-9C22H28ClN3O4
2-Bromo-N-[2-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20BrN3O, CAS 717873-88-6
2-Bromo-N-[2-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 717873-88-6C18H20BrN3O
5-Chloro-2-methoxy-N-[2-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H22ClN3O2, CAS 830344-95-1
5-Chloro-2-methoxy-N-[2-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 830344-95-1C19H22ClN3O2
3-Chloro-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-4-methylbenzamide chemical structure, C21H23Cl2N3O2, CAS 831242-69-4
3-Chloro-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-4-methylbenzamide
CAS 831242-69-4C21H23Cl2N3O2