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Murcko scaffold

Ring system with 5 rings and 25 atoms

70 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
25
Chemicals
70
With full pages
8
Scaffold SMILES

c1ccc(C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 70 chemicals

1H-Indole-2-carboxylic acid, 3,3'-((2-chlorophenyl)methylene)bis(1-methyl- chemical structure, C27H21ClN2O4, CAS 58123-48-1
1H-Indole-2-carboxylic acid, 3,3'-((2-chlorophenyl)methylene)bis(1-methyl-
CAS 58123-48-1C27H21ClN2O4
4-(Di(1H-indol-3-yl)methyl)aniline chemical structure, C23H19N3, CAS 6340-90-5
4-(Di(1H-indol-3-yl)methyl)aniline
CAS 6340-90-5C23H19N3
2-Methyl-3-[(2-methyl-1H-indol-3-yl)-phenylmethyl]-1H-indole chemical structure, C25H22N2, CAS 17371-59-4
2-Methyl-3-[(2-methyl-1H-indol-3-yl)-phenylmethyl]-1H-indole
CAS 17371-59-4C25H22N2
Phenol, 2-[bis(2-methyl-1H-indol-3-yl)methyl]- chemical structure, C25H22N2O, CAS 110200-68-5
Phenol, 2-[bis(2-methyl-1H-indol-3-yl)methyl]-
CAS 110200-68-5C25H22N2O
4-[Bis(2-methyl-1H-indol-3-yl)methyl]aniline chemical structure, C25H23N3, CAS 7770-54-9
4-[Bis(2-methyl-1H-indol-3-yl)methyl]aniline
CAS 7770-54-9C25H23N3
RefChem:382257 chemical structure, C23H17N3O2, CAS 7501-91-9
RefChem:382257
CAS 7501-91-9C23H17N3O2
4-[Bis(2-methyl-1H-indol-3-yl)methyl]-N,N-dimethylaniline chemical structure, C27H27N3, CAS 16383-51-0
4-[Bis(2-methyl-1H-indol-3-yl)methyl]-N,N-dimethylaniline
CAS 16383-51-0C27H27N3
3-[(2-Iodophenyl)-(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole chemical structure, C25H21IN2, CAS 305863-23-4
3-[(2-Iodophenyl)-(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole
CAS 305863-23-4C25H21IN2
1H-Indole, 3,3'-[(3,4-dimethoxyphenyl)methylene]bis[2-methyl- chemical structure, C27H26N2O2, CAS 199605-23-7
1H-Indole, 3,3'-[(3,4-dimethoxyphenyl)methylene]bis[2-methyl-
CAS 199605-23-7C27H26N2O2
1H-Indole, 3,3'-[(4-methoxyphenyl)methylene]bis[2-methyl- chemical structure, C26H24N2O, CAS 33895-69-1
1H-Indole, 3,3'-[(4-methoxyphenyl)methylene]bis[2-methyl-
CAS 33895-69-1C26H24N2O
3-[(4-Ethoxyphenyl)-(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole chemical structure, C27H26N2O, CAS 331862-26-1
3-[(4-Ethoxyphenyl)-(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole
CAS 331862-26-1C27H26N2O
2-Methyl-3-[(2-methyl-1H-indol-3-yl)(2,4,6-trimethoxyphenyl)methyl]-1H-indole chemical structure, C28H28N2O3, CAS 486995-81-7
2-Methyl-3-[(2-methyl-1H-indol-3-yl)(2,4,6-trimethoxyphenyl)methyl]-1H-indole
CAS 486995-81-7C28H28N2O3
4-[Bis(1H-indol-3-yl)methyl]benzene-1,2-diol chemical structure, C23H18N2O2, CAS 39215-16-2
4-[Bis(1H-indol-3-yl)methyl]benzene-1,2-diol
CAS 39215-16-2C23H18N2O2
2-[Bis(1H-indol-3-yl)methyl]-4-methoxyphenol chemical structure, C24H20N2O2, CAS 486443-09-8
2-[Bis(1H-indol-3-yl)methyl]-4-methoxyphenol
CAS 486443-09-8C24H20N2O2
3-[Bis(1H-indol-3-yl)methyl]-4-bromophenol chemical structure, C23H17BrN2O, CAS 486443-03-2
3-[Bis(1H-indol-3-yl)methyl]-4-bromophenol
CAS 486443-03-2C23H17BrN2O
{2-[Bis(2-methyl-1H-indol-3-yl)methyl]-6-methoxyphenoxy}acetic acid chemical structure, C28H26N2O4, CAS 486995-89-5
{2-[Bis(2-methyl-1H-indol-3-yl)methyl]-6-methoxyphenoxy}acetic acid
CAS 486995-89-5C28H26N2O4
3-[1H-Indol-3-yl-(2-methoxyphenyl)methyl]-1H-indole chemical structure, C24H20N2O, CAS 692285-77-1
3-[1H-Indol-3-yl-(2-methoxyphenyl)methyl]-1H-indole
CAS 692285-77-1C24H20N2O
2-(4-(Di(1H-indol-3-yl)methyl)-2-methoxyphenoxy)acetic acid chemical structure, C26H22N2O4, CAS 692288-67-8
2-(4-(Di(1H-indol-3-yl)methyl)-2-methoxyphenoxy)acetic acid
CAS 692288-67-8C26H22N2O4
3-[1H-Indol-3-yl-(2,3,4-trimethoxyphenyl)methyl]-1H-indole chemical structure, C26H24N2O3, CAS 692288-77-0
3-[1H-Indol-3-yl-(2,3,4-trimethoxyphenyl)methyl]-1H-indole
CAS 692288-77-0C26H24N2O3
DIM-C-pPhOH chemical structure, C23H18N2O, CAS 151358-47-3
DIM-C-pPhOH
CAS 151358-47-3C23H18N2O
4-[Bis(1H-indol-3-yl)methyl]-2-ethoxyphenol chemical structure, C25H22N2O2, CAS 692290-53-2
4-[Bis(1H-indol-3-yl)methyl]-2-ethoxyphenol
CAS 692290-53-2C25H22N2O2
3-[1H-Indol-3-yl-(3-nitrophenyl)methyl]-1H-indole chemical structure, C23H17N3O2, CAS 33948-93-5
3-[1H-Indol-3-yl-(3-nitrophenyl)methyl]-1H-indole
CAS 33948-93-5C23H17N3O2
4-[Bis(1H-indol-3-yl)methyl]-2-chloro-6-ethoxyphenol chemical structure, C25H21ClN2O2, CAS 693827-98-4
4-[Bis(1H-indol-3-yl)methyl]-2-chloro-6-ethoxyphenol
CAS 693827-98-4C25H21ClN2O2
4-[Bis(1H-indol-3-yl)methyl]-5-chloro-2-methoxyphenol chemical structure, C24H19ClN2O2, CAS 693830-62-5
4-[Bis(1H-indol-3-yl)methyl]-5-chloro-2-methoxyphenol
CAS 693830-62-5C24H19ClN2O2