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Murcko scaffold

1,4-Dioxane-2,6-dione scaffold

7 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1COCC(=O)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Dioxane-2,6-dione page
Murcko scaffold O=C1COCC(=O)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1,4-Dioxane-2,6-dione chemical structure, C4H4O4, CAS 4480-83-5
1,4-Dioxane-2,6-dione
CAS 4480-83-5C4H4O4
Tetramethyl-1,4-dioxane-2,6-dione chemical structure, C8H12O4, CAS 58607-24-2
Tetramethyl-1,4-dioxane-2,6-dione
CAS 58607-24-2C8H12O4
3,5-Dimethyl-1,4-dioxane-2,6-dione chemical structure, C6H8O4, CAS 828258-84-0
3,5-Dimethyl-1,4-dioxane-2,6-dione
CAS 828258-84-0C6H8O4
3,3-Dimethyl-1,4-dioxane-2,6-dione chemical structure, C6H8O4, CAS 2171890-40-5
3,3-Dimethyl-1,4-dioxane-2,6-dione
CAS 2171890-40-5C6H8O4
2-Methyl-3,5-dioxo-1,4-dioxane-2-carboxylic acid chemical structure, C6H6O6, CAS 540722-96-1
2-Methyl-3,5-dioxo-1,4-dioxane-2-carboxylic acid
CAS 540722-96-1C6H6O6
3-Ethyl-5-methyl-1,4-dioxane-2,6-dione chemical structure, C7H10O4, CAS 861540-32-1
3-Ethyl-5-methyl-1,4-dioxane-2,6-dione
CAS 861540-32-1C7H10O4
1,4-Dioxane-2,6-dione-d4 chemical structure, C4H4O4, CAS 2363779-25-1
1,4-Dioxane-2,6-dione-d4
CAS 2363779-25-1C4H4O4