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Murcko scaffold

Ring system with 3 rings and 16 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
14
With full pages
2
Scaffold SMILES

c1ccc(Cc2n[nH]c3ncncc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2n[nH]c3ncncc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-tert-Butyl-3-(2,5-dimethylbenzyl)-1H-pyrazolo(3,4-D)pyrimidin-4-amine chemical structure, C18H23N5, CAS 895537-31-2
1-tert-Butyl-3-(2,5-dimethylbenzyl)-1H-pyrazolo(3,4-D)pyrimidin-4-amine
CAS 895537-31-2C18H23N5
3-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C12H11N5, CAS 42754-71-2
3-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 42754-71-2C12H11N5
1-tert-Butyl-3-[(3,5-difluorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H17F2N5, CAS 956025-95-9
1-tert-Butyl-3-[(3,5-difluorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 956025-95-9C16H17F2N5
3-(3-Bromobenzyl)-1-Tert-Butyl-1H-Pyrazolo[3,4-D]pyrimidin-4-Amine chemical structure, C16H18BrN5, CAS 956025-99-3
3-(3-Bromobenzyl)-1-Tert-Butyl-1H-Pyrazolo[3,4-D]pyrimidin-4-Amine
CAS 956025-99-3C16H18BrN5
3MB-PP1 chemical structure, C17H21N5, CAS 956025-83-5
3MB-PP1
CAS 956025-83-5C17H21N5
3-(3-Iodobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C16H18IN5, CAS 1174182-24-1
3-(3-Iodobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 1174182-24-1C16H18IN5
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine chemical structure, C16H19N5, CAS 186895-85-2
4-Amino-1-tert-butyl-3-benzylpyrazolo[3,4-d]pyrimidine
CAS 186895-85-2C16H19N5
T338C Src-IN-2 chemical structure, C17H18FN5O, CAS 1351927-00-8
T338C Src-IN-2
CAS 1351927-00-8C17H18FN5O
T338C Src-IN-1 chemical structure, C17H20N6O2S, CAS 1351926-90-3
T338C Src-IN-1
CAS 1351926-90-3C17H20N6O2S
N-[3-[(4-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenyl]ethenesulfonamide chemical structure, C15H16N6O2S, CAS 1351927-01-9
N-[3-[(4-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenyl]ethenesulfonamide
CAS 1351927-01-9C15H16N6O2S
4-Amino-1-tert-butyl-3-(2,3-dimethylbenzyl)pyrazolo[3,4-d]pyrimidine chemical structure, C18H23N5, CAS 956026-24-7
4-Amino-1-tert-butyl-3-(2,3-dimethylbenzyl)pyrazolo[3,4-d]pyrimidine
CAS 956026-24-7C18H23N5
(4-Amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-phenyl-methanol chemical structure, C16H19N5O, CAS 1151649-93-2
(4-Amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-phenyl-methanol
CAS 1151649-93-2C16H19N5O
2OH-Bnpp1 chemical structure, C16H19N5O, CAS 833481-73-5
2OH-Bnpp1
CAS 833481-73-5C16H19N5O
(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-(2,3-dichlorophenyl)methanol chemical structure, C15H15Cl2N5O, CAS 1428640-39-4
(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-(2,3-dichlorophenyl)methanol
CAS 1428640-39-4C15H15Cl2N5O