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Murcko scaffold

Ring system with 2 rings and 19 atoms

10 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 19
Chemicals: 10
With full pages: 4

Scaffold SMILES

O=C(C=Cc1ccccc1)NCCN1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccccc1)NCCN1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(E)-3-(2,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)prop-2-enamide chemical structure, C15H18Cl2N2O2, CAS 1164550-21-3

(E)-3-(2,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)prop-2-enamide

CAS 1164550-21-3C₁₅H₁₈Cl₂N₂O₂

3-(4-Chloro-phenyl)-N-(2-morpholin-4-yl-ethyl)-acrylamide chemical structure, C15H19ClN2O2, CAS 57168-94-2

3-(4-Chloro-phenyl)-N-(2-morpholin-4-yl-ethyl)-acrylamide

CAS 57168-94-2C₁₅H₁₉ClN₂O₂

(2E)-2-Cyano-3-[4-(dimethylamino)phenyl]-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide chemical structure, C18H24N4O2, CAS 380575-10-0

(2E)-2-Cyano-3-[4-(dimethylamino)phenyl]-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide

CAS 380575-10-0C₁₈H₂₄N₄O₂

(E)-N-(2-Morpholin-4-ylethyl)-3-(3-nitrophenyl)prop-2-enamide chemical structure, C15H19N3O4, CAS 1164523-18-5

(E)-N-(2-Morpholin-4-ylethyl)-3-(3-nitrophenyl)prop-2-enamide

CAS 1164523-18-5C₁₅H₁₉N₃O₄

3-(2-Chlorophenyl)-N-[2-(4-morpholinyl)ethyl]acrylamide chemical structure, C15H19ClN2O2, CAS 1164564-88-8

3-(2-Chlorophenyl)-N-[2-(4-morpholinyl)ethyl]acrylamide

CAS 1164564-88-8C₁₅H₁₉ClN₂O₂

(E)-N-(2-Morpholin-4-ylethyl)-3-(2-nitrophenyl)prop-2-enamide chemical structure, C15H19N3O4, CAS 600122-88-1

(E)-N-(2-Morpholin-4-ylethyl)-3-(2-nitrophenyl)prop-2-enamide

CAS 600122-88-1C₁₅H₁₉N₃O₄

3-(4-Bromophenyl)-2-cyano-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide chemical structure, C16H18BrN3O2, CAS 518350-88-4

3-(4-Bromophenyl)-2-cyano-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide

CAS 518350-88-4C₁₆H₁₈BrN₃O₂

(E)-2-Cyano-3-(4-methoxyphenyl)-N-(2-morpholin-4-ylethyl)prop-2-enamide chemical structure, C17H21N3O3, CAS 647036-20-2

(E)-2-Cyano-3-(4-methoxyphenyl)-N-(2-morpholin-4-ylethyl)prop-2-enamide

CAS 647036-20-2C₁₇H₂₁N₃O₃

2-(Acetylamino)-N-[2-(4-morpholinyl)ethyl]-3-phenyl-2-propenamide chemical structure, C17H23N3O3, CAS 19392-82-6

2-(Acetylamino)-N-[2-(4-morpholinyl)ethyl]-3-phenyl-2-propenamide

CAS 19392-82-6C₁₇H₂₃N₃O₃

2-Cyano-N-[2-(morpholin-4-yl)ethyl]-3-phenylprop-2-enamide hydrochloride chemical structure, C16H20ClN3O2, CAS 1808374-23-3

2-Cyano-N-[2-(morpholin-4-yl)ethyl]-3-phenylprop-2-enamide hydrochloride

CAS 1808374-23-3C₁₆H₂₀ClN₃O₂