Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

2-Benzylsulfanyl-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one scaffold

93 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 28
Chemicals: 93
With full pages: 33

Scaffold SMILES

O=c1c2c3c(sc2nc(SCc2ccccc2)n1-c1ccccc1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Benzylsulfanyl-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one page

Murcko scaffold O=c1c2c3c(sc2nc(SCc2ccccc2)n1-c1ccccc1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 93 chemicals

3-(4-Methoxyphenyl)-2-((3-(trifluoromethyl)benzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C25H21F3N2O2S2, CAS 477329-57-0

3-(4-Methoxyphenyl)-2-((3-(trifluoromethyl)benzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477329-57-0C₂₅H₂₁F₃N₂O₂S₂

3-(4-Chlorophenyl)-2-{[3-(trifluoromethyl)benzyl]sulfanyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C24H18ClF3N2OS2, CAS 499102-83-9

3-(4-Chlorophenyl)-2-{[3-(trifluoromethyl)benzyl]sulfanyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-83-9C₂₄H₁₈ClF₃N₂OS₂

2-[(4-Bromobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C24H21BrN2O2S2, CAS 477332-86-8

2-[(4-Bromobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 477332-86-8C₂₄H₂₁BrN₂O₂S₂

4-(((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)methyl)benzonitrile chemical structure, C25H21N3O2S2, CAS 477329-31-0

4-(((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)methyl)benzonitrile

CAS 477329-31-0C₂₅H₂₁N₃O₂S₂

3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H17Cl3N2OS2, CAS 499102-91-9

3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-91-9C₂₃H₁₇Cl₃N₂OS₂

3-(4-Chlorophenyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C24H21ClN2O2S2, CAS 499102-48-6

3-(4-Chlorophenyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-48-6C₂₄H₂₁ClN₂O₂S₂

2-((3,4-Dichlorobenzyl)sulfanyl)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C24H20Cl2N2O2S2, CAS 477330-43-1

2-((3,4-Dichlorobenzyl)sulfanyl)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477330-43-1C₂₄H₂₀Cl₂N₂O₂S₂

3-(4-Bromophenyl)-2-[(2-methylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C24H21BrN2OS2, CAS 498546-94-4

3-(4-Bromophenyl)-2-[(2-methylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 498546-94-4C₂₄H₂₁BrN₂OS₂

3-(4-Chlorophenyl)-2-[(2,5-dimethylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C25H23ClN2OS2, CAS 499102-84-0

3-(4-Chlorophenyl)-2-[(2,5-dimethylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-84-0C₂₅H₂₃ClN₂OS₂

3-(4-Methoxyphenyl)-2-((2-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C25H24N2O2S2, CAS 477331-49-0

3-(4-Methoxyphenyl)-2-((2-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477331-49-0C₂₅H₂₄N₂O₂S₂

3-(4-Ethoxyphenyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C26H26N2O3S2, CAS 499125-35-8

3-(4-Ethoxyphenyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499125-35-8C₂₆H₂₆N₂O₃S₂

2-[(2-Chlorobenzyl)sulfanyl]-3-(4-chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H18Cl2N2OS2, CAS 499102-80-6

2-[(2-Chlorobenzyl)sulfanyl]-3-(4-chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-80-6C₂₃H₁₈Cl₂N₂OS₂

4-({[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}methyl)benzoic acid chemical structure, C25H22N2O4S2, CAS 477330-71-5

4-({[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}methyl)benzoic acid

CAS 477330-71-5C₂₅H₂₂N₂O₄S₂

3-(4-Methoxyphenyl)-2-((4-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C25H24N2O2S2, CAS 477332-81-3

3-(4-Methoxyphenyl)-2-((4-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477332-81-3C₂₅H₂₄N₂O₂S₂

2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(4-chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H17Cl2FN2OS2, CAS 499102-76-0

2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(4-chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-76-0C₂₃H₁₇Cl₂FN₂OS₂

3-(4-Chlorophenyl)-2-[(3,4-dichlorobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H17Cl3N2OS2, CAS 499102-67-9

3-(4-Chlorophenyl)-2-[(3,4-dichlorobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-67-9C₂₃H₁₇Cl₃N₂OS₂

2-[(3-Chlorobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one chemical structure, C24H21ClN2O2S2, CAS 477333-56-5

2-[(3-Chlorobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one

CAS 477333-56-5C₂₄H₂₁ClN₂O₂S₂

3-(4-Methoxyphenyl)-2-((3-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C25H24N2O2S2, CAS 477331-37-6

3-(4-Methoxyphenyl)-2-((3-methylbenzyl)sulfanyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477331-37-6C₂₅H₂₄N₂O₂S₂

3-(4-Chlorophenyl)-2-[(2-methylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C24H21ClN2OS2, CAS 499102-47-5

3-(4-Chlorophenyl)-2-[(2-methylbenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499102-47-5C₂₄H₂₁ClN₂OS₂

2-[(2,6-Dichlorobenzyl)sulfanyl]-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C25H22Cl2N2O2S2, CAS 499125-45-0

2-[(2,6-Dichlorobenzyl)sulfanyl]-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 499125-45-0C₂₅H₂₂Cl₂N₂O₂S₂

2-[(4-tert-Butylbenzyl)sulfanyl]-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one chemical structure, C29H32N2O2S2, CAS 477318-98-2

2-[(4-tert-Butylbenzyl)sulfanyl]-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one

CAS 477318-98-2C₂₉H₃₂N₂O₂S₂

2-[(3-Fluorobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one chemical structure, C24H21FN2O2S2, CAS 477330-56-6

2-[(3-Fluorobenzyl)sulfanyl]-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one

CAS 477330-56-6C₂₄H₂₁FN₂O₂S₂

2-((2,5-Dimethylbenzyl)sulfanyl)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one chemical structure, C26H26N2O2S2, CAS 477328-99-7

2-((2,5-Dimethylbenzyl)sulfanyl)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydro(1)benzothieno(2,3-D)pyrimidin-4(3H)-one

CAS 477328-99-7C₂₆H₂₆N₂O₂S₂

3-(4-Methoxyphenyl)-2-[(4-nitrobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one chemical structure, C24H21N3O4S2, CAS 477331-59-2

3-(4-Methoxyphenyl)-2-[(4-nitrobenzyl)sulfanyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-D]pyrimidin-4(3H)-one

CAS 477331-59-2C₂₄H₂₁N₃O₄S₂