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Murcko scaffold

Ring system with 2 rings and 15 atoms

101 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
101
With full pages
37
Scaffold SMILES

S=C(Nc1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 101 chemicals

N-(4-Methoxyphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C13H19N3OS, CAS 109219-12-7
N-(4-Methoxyphenyl)-4-methylpiperazine-1-carbothioamide
CAS 109219-12-7C13H19N3OS
Ethyl 4-[(4-methoxyphenyl)carbamothioyl]piperazine-1-carboxylate chemical structure, C15H21N3O3S, CAS 430470-43-2
Ethyl 4-[(4-methoxyphenyl)carbamothioyl]piperazine-1-carboxylate
CAS 430470-43-2C15H21N3O3S
Ethyl 4-[(4-chlorophenyl)carbamothioyl]piperazine-1-carboxylate chemical structure, C14H18ClN3O2S, CAS 431057-36-2
Ethyl 4-[(4-chlorophenyl)carbamothioyl]piperazine-1-carboxylate
CAS 431057-36-2C14H18ClN3O2S
4-Ethyl-N-(4-methoxyphenyl)piperazine-1-carbothioamide chemical structure, C14H21N3OS, CAS 690702-93-3
4-Ethyl-N-(4-methoxyphenyl)piperazine-1-carbothioamide
CAS 690702-93-3C14H21N3OS
N-(3,4-Dichlorophenyl)-4-ethylpiperazine-1-carbothioamide chemical structure, C13H17Cl2N3S, CAS 309942-81-2
N-(3,4-Dichlorophenyl)-4-ethylpiperazine-1-carbothioamide
CAS 309942-81-2C13H17Cl2N3S
Ethyl 4-[(4-fluorophenyl)carbamothioyl]piperazine-1-carboxylate chemical structure, C14H18FN3O2S, CAS 330865-90-2
Ethyl 4-[(4-fluorophenyl)carbamothioyl]piperazine-1-carboxylate
CAS 330865-90-2C14H18FN3O2S
4-Methyl-N-phenylpiperazine-1-carbothioamide chemical structure, C12H17N3S, CAS 6336-69-2
4-Methyl-N-phenylpiperazine-1-carbothioamide
CAS 6336-69-2C12H17N3S
4-Ethyl-N-phenylpiperazine-1-carbothioamide chemical structure, C13H19N3S, CAS 332032-77-6
4-Ethyl-N-phenylpiperazine-1-carbothioamide
CAS 332032-77-6C13H19N3S
Ethyl 4-(phenylcarbamothioyl)piperazine-1-carboxylate chemical structure, C14H19N3O2S, CAS 332033-11-1
Ethyl 4-(phenylcarbamothioyl)piperazine-1-carboxylate
CAS 332033-11-1C14H19N3O2S
N-(4-Bromophenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C12H16BrN3S, CAS 356578-71-7
N-(4-Bromophenyl)-4-methylpiperazine-1-carbothioamide
CAS 356578-71-7C12H16BrN3S
N-(2,4-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide chemical structure, C15H23N3OS, CAS 433248-61-4
N-(2,4-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide
CAS 433248-61-4C15H23N3OS
N-(3,5-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide chemical structure, C15H23N3OS, CAS 433255-18-6
N-(3,5-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide
CAS 433255-18-6C15H23N3OS
N-(3,5-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C14H21N3S, CAS 433257-81-9
N-(3,5-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433257-81-9C14H21N3S
N-(2,5-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C14H21N3S, CAS 147752-08-7
N-(2,5-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide
CAS 147752-08-7C14H21N3S
N-(2,4-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C14H21N3S, CAS 433259-11-1
N-(2,4-Dimethylphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433259-11-1C14H21N3S
N-(3-Chloro-2-methylphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C13H18ClN3S, CAS 433307-07-4
N-(3-Chloro-2-methylphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433307-07-4C13H18ClN3S
N-(4-Chlorophenyl)-4-ethylpiperazine-1-carbothioamide chemical structure, C13H18ClN3S, CAS 309943-90-6
N-(4-Chlorophenyl)-4-ethylpiperazine-1-carbothioamide
CAS 309943-90-6C13H18ClN3S
N-(4-Chloro-2-methylphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C13H18ClN3S, CAS 433315-92-5
N-(4-Chloro-2-methylphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433315-92-5C13H18ClN3S
N-(2,4-Dichlorophenyl)-4-ethylpiperazine-1-carbothioamide chemical structure, C13H17Cl2N3S, CAS 406927-38-6
N-(2,4-Dichlorophenyl)-4-ethylpiperazine-1-carbothioamide
CAS 406927-38-6C13H17Cl2N3S
N-(2,5-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide chemical structure, C15H23N3OS, CAS 481690-07-7
N-(2,5-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide
CAS 481690-07-7C15H23N3OS
N-(3,5-Dimethoxyphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C14H21N3O2S, CAS 433321-97-2
N-(3,5-Dimethoxyphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433321-97-2C14H21N3O2S
N-(2,4-Dimethoxyphenyl)-4-methylpiperazine-1-carbothioamide chemical structure, C14H21N3O2S, CAS 433322-51-1
N-(2,4-Dimethoxyphenyl)-4-methylpiperazine-1-carbothioamide
CAS 433322-51-1C14H21N3O2S
N-(4-Chloro-2-methylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide chemical structure, C14H20ClN3OS, CAS 433324-13-1
N-(4-Chloro-2-methylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide
CAS 433324-13-1C14H20ClN3OS
N-(2,3-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide chemical structure, C15H23N3OS, CAS 437734-67-3
N-(2,3-Dimethylphenyl)-4-(2-hydroxyethyl)piperazine-1-carbothioamide
CAS 437734-67-3C15H23N3OS